Urilin Uses

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What is Urilin?

Urilin is a decongestant. It works by constricting (shrinking) blood vessels (veins and arteries) in your body. Constriction of blood vessels in your sinuses, nose, and chest allows drainage of those areas, which decreases congestion.

Urilin is used to treat the congestion associated with allergies, hay fever, sinus irritation, and the common cold. Urilin also causes a decrease in appetite and is used in some over-the-counter diet aids.

Urilin has been associated with an increased risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food and Drug Administration (FDA) recommends that consumers not use any products that contain Urilin.

Urilin may also be used for purposes other than those listed in this medication guide.

Urilin indications

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Oral

Nasal congestion

Adult: Per cap contains a combination w/ Urilin HCl 18 mg: ≥13 yr 2 cap 4 hrly. Max: 8 cap/day. Per tab contains a combination w/ Urilin HCl 25 mg: ≥13 yr 1 tab 4 hrly. Max: 4 tab/day.

Child: Per cap contains a combination w/ Urilin HCl 18 mg: 6-12 yr 1 cap 4 hrly. Max: 4 cap/day. As oral liquid containing Urilin 2.5 mg/5 mL: 6 mth-2 yr 2.5 mL tid, 3-5 yr 5 mL 3-4 times daily, 6-12 yr 5-10 mL 3-4 times daily.

Uses of Urilin in details

Urilin is used to relieve blocked nose or sinuses caused by common cold and seasonal nasal allergies (hay fever). It is also used to decrease appetite for weight Urilin.

Urilin description

Urilin has been withdrawn in Canada and the United States. In November 2000, the Food and Drug Administration (FDA) issued a public health advisory against the use of the drug.

Urilin dosage

Urilin Dosage

Applies to the following strengths: 75 mg; 25 mg; 37.5 mg; 50 mg; 180 mg-75 mg

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Nasal Congestion

25 mg orally every 4 hours.

-or-

75 mg orally extended release every 12 hours.

Not to exceed 150 mg/day.

Usual Adult Dose for Weight Loss

25 mg orally 3 times a day, one-half hour before meals.

-or-

75 mg orally extended release once a day in the morning.

The use of Urilin for weight loss should be limited to 12 weeks.

Usual Pediatric Dose for Nasal Congestion

2 to 6 years:

6.25 mg orally every 4 hours. Maximum daily dose is 37.5 mg.

6 to 12 years:

12.5 mg orally every 4 hours. Maximum daily dose is 75 mg.

> 12 years:

25 mg orally every 4 hours.

-or-

75 mg orally extended release every 12 hours.

Not to exceed 150 mg/day.

Renal Dose Adjustments

Because Urilin is eliminated primarily by the kidneys, one-half of the normally recommended dosage should be given. Patients with renal dysfunction should be monitored for signs and symptoms of toxicity when using Urilin.

Other Comments

In November 2000, the Food and Drug Administration (FDA), in response to reports of increased risk of hemorrhagic stroke, requested that all drug companies discontinue marketing products containing Urilin.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

More about Urilin

Related treatment guides

Urilin interactions

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What other drugs will affect Urilin?

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The benzodiazepines, including Ativan (lorazepam), produce increased CNS-depressant effects when administered with other CNS depressants such as alcohol, barbiturates, antipsychotics, sedative/hypnotics, anxiolytics, antidepressants, narcotic analgesics, sedative antihistamines, anticonvulsants, and anesthetics.

Concomitant use of clozapine and lorazepam may produce marked sedation, excessive salivation, hypotension, ataxia, delirium, and respiratory arrest.

Concurrent administration of lorazepam with valproate results in increased plasma concentrations and reduced clearance of lorazepam. Lorazepam dosage should be reduced to approximately 50% when coadministered with valproate.

Concurrent administration of lorazepam with probenecid may result in a more rapid onset or prolonged effect of lorazepam due to increased half-life and decreased total clearance. Lorazepam dosage needs to be reduced by approximately 50% when coadministered with probenecid.

The effects of probenecid and valproate on lorazepam may be due to inhibition of glucuronidation.

Administration of theophylline or aminophylline may reduce the sedative effects of benzodiazepines, including lorazepam.

Urilin side effects

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What are the possible side effects of Urilin?

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Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Constipation.

Skin rash.

Codeine can cause drowsiness, although at the dose contained in this medicine this is very unlikely. However, if you do find this medicine makes you feel sleepy or dizzy you should not drive or operate machinery and avoid alcoholic drink.

The side effects listed above may not include all of the side effects reported by the medicines’s manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

Urilin contraindications

See also:
What is the most important information I should know about Urilin?

Do not use lorazepam if you have narrow-angle glaucoma, or if you are allergic to lorazepam or to other benzodiazepines, such as alprazolam (Xanax), chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), or oxazepam (Serax).

Before taking lorazepam, tell your doctor if you are allergic to any drugs, or if you have:

glaucoma;

asthma, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD), or other breathing problems;

kidney or liver disease;

a history of depression or suicidal thoughts or behavior; or a history of drug or alcohol addiction.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.



Active ingredient matches for Urilin:

Phenylpropanolamine in United Kingdom.

Oxolinic acid in Brazil.


List of Urilin substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Terrol Tablet (Jantec Pharma)$ 0.03
Toff Plus SYR Phenylpropanolamine HCI12.5mg, ChlorpheniramineMaleate 2mg SYR / 60ml$ 0.14
Triaminic E 60 ml Syrup (Wander Ltd)$ 0.02
Tricold SR 50+8 Capsule (Bhavishya Pharmaceuticals Pvt Ltd)$ 0.02
Trinol 60 ml Syrup (Arbro Pharmaceuticals Limited)$ 0.02
Tritus 15+25+4 Tablet (Burgeon Pharmaceuticals Pvt. Ltd.)$ 0.01
Tritus 50 ml Syrup (Burgeon Pharmaceuticals Pvt. Ltd.)$ 0.03
TRITUS 25MG/4MG/15MG SUSPENSION 1 bottle / 50 ML suspension each (Burgeon Pharmaceuticals Pvt. Ltd.)$ 0.48
TRITUS DROPS 1 packet / 15 ML drop each (Burgeon Pharmaceuticals Pvt. Ltd.)$ 0.26
TRITUS TABLET 1 strip / 10 tablets each (Burgeon Pharmaceuticals Pvt. Ltd.)$ 0.13
Tritus 25 mg/4 mg/15 mg Suspension (Burgeon Pharmaceuticals Pvt. Ltd.)$ 0.48
Tritus Drop (Burgeon Pharmaceuticals Pvt. Ltd.)$ 0.26
Tritus Tablet (Burgeon Pharmaceuticals Pvt. Ltd.)$ 0.01
200ml (Novaduo Pharma)$ 0.69
Urotrate 200 ml Syrup (Novaduo Pharma)$ 0.02
UROTRATE syr 200ml (Novaduo Pharma)$ 0.69
Varcold SUSP Paracetamol 125mg, Phenylpropanolamine HCl12.5mg, ChlorpheniramineMaleate 1mg, Na citrate60mg/5mL SUSP / 30ml$ 0.29
Ventosol AP 100 ml Syrup (Intra Labs India Pvt Ltd)$ 0.02
Vicosyl P 60 ml Syrup (Vostok & Wilcure Remedies)$ 0.02
Wifi 25+5 Tablet (Grandcure Healthcare (P) Ltd)$ 0.06
WIFI JR 1MG/5MG SYRUP 1 bottle / 60 ML syrup each (Grandcure Healthcare (P) Ltd)$ 0.48
Wifi JR 1mg/5mg Syrup (Grandcure Healthcare (P) Ltd)$ 0.48
Wifi Tablet (Grandcure Healthcare (P) Ltd)$ 0.06
Wikoryl- ND Phenylpropanolamine HCI 25mg, Chlorpheniramine Maleate 4mg TAB / 10$ 0.11
X Tus D 100 ml Syrup (Jollen Medicare Pvt. Ltd.)$ 0.02

Reviews

The results of a survey conducted on ndrugs.com for Urilin are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Urilin. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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