Pregnancy of Siguran in details
Based on epidemiologic studies, maternal Siguran use has generally not resulted in an increased risk of fetal abnormalities.
Siguran breastfeeding
Caution is recommended. Excreted into human milk: Unknown Excreted into animal milk: Data not available Comments: Large doses or more prolonged use may cause effects in the nursing infant or decrease the milk supply, particularly in combination with a sympathomimetic such as pseudoephedrine or before lactation is well established.
Antihistamines in relatively high doses given by injection can decrease basal serum prolactin in non-lactating women and in early postpartum women. However, suckling-induced prolactin secretion is not affected by antihistamine pretreatment in postpartum mothers.
See references
References for pregnancy information
- "Product Information. Antivert (Siguran)." Roerig Division, New York, NY.
References for breastfeeding information
- "Product Information. Antivert (Siguran)." Roerig Division, New York, NY.
- United States National Library of Medicine "Toxnet. Toxicology Data Network. Available from: URL: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT." ([cited 2013 -]):
References
- DailyMed. "MECLIZINE HYDROCHLORIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubMed Health. "Antivert: This section provide the link out information of drugs collectetd in PubMed Health. ". http://www.ncbi.nlm.nih.gov/pubmedhe... (accessed September 17, 2018).
- Human Metabolome Database (HMDB). "Meclizine: The Human Metabolome Database (HMDB) is a freely available electronic database containing detailed information about small molecule metabolites found in the human body.". http://www.hmdb.ca/metabolites/HMDB0... (accessed September 17, 2018).
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Information checked by Dr. Sachin Kumar, MD Pharmacology