What is Siguran?
Siguran (Siguran) is an antihistamine that reduces the effects of natural chemical histamine in the body.
Siguran is used to treat or prevent nausea, vomiting, and dizziness caused by motion sickness. It is also used to treat symptoms of vertigo (dizziness or spinning sensation) caused by disease that affects your inner ear.
Siguran may also be used for purposes not listed in this medication guide.
Siguran indications
Siguran is an antihistamine and anticholinergic. It works by blocking a chemical messenger in the brain, which helps to reduce or prevent vomiting.
Siguran is used to treat or prevent nausea, vomiting, and dizziness caused by motion sickness. It is also used for vertigo (or dizziness) caused by certain inner ear problems.
How should I use Siguran?
Use Siguran chewable tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Siguran chewable tablets by mouth with or without food.
- Siguran chewable tablets may be chewed or swallowed whole.
- For prevention of motion sickness, take Siguran chewable tablets at least 1 hour before activity or travel.
- Use Siguran chewable tablets exactly as directed on the package, unless instructed differently by your doctor. Follow any warnings and precautions on the label.
- If you miss a dose of Siguran chewable tablets and you are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Siguran chewable tablets.
Uses of Siguran in details
Siguran is an antihistamine that is used to prevent and treat nausea, vomiting, and dizziness caused by motion sickness. It may also be used to reduce dizziness and loss of balance (vertigo) caused by inner ear problems.
How to use Siguran
Follow all directions on the product package. If your doctor has prescribed this medication, take it as directed. If you are uncertain about any of the information, consult your doctor or pharmacist.
Take this medication by mouth with or without food. The chewable tablets should be chewed thoroughly before being swallowed.
The dosage is based on your medical condition and response to treatment. Do not increase your dose or take this medication more often than directed.
To prevent motion sickness, take the first dose one hour before starting activity such as travel.
Tell your doctor if your condition does not improve or if it worsens.
Siguran description
A histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness. [PubChem]
Siguran dosage
Siguran Dosage
Generic name: Siguran HYDROCHLORIDE 12.5mg
Dosage form: tablet
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Vertigo
For the control of vertigo associated with diseases affecting the vestibular system, the recommended dose is 25 to 100 mg daily, in divided dosage, depending upon clinical response.
Motion Sickness
The initial dose of 25 to 50 mg of Siguran should be taken one hour prior to embarkation for protection against motion sickness. Thereafter, the dose may be repeated every 24 hours for the duration of the journey.
More about Siguran (Siguran)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- En Espanol
- 7 Reviews - Add your own review/rating
- Generic Availability
Consumer resources
- Siguran
- Siguran (Advanced Reading)
- Other brands: Siguran, Meclicot, Travel Sickness, Dramamine Less Drowsy, More (4) »
Professional resources
- Siguran (FDA)
- Siguran Hydrochloride (AHFS Monograph)
Related treatment guides
- Vertigo
- Motion Sickness
- Nausea/Vomiting
Siguran interactions
See also:
What other drugs will affect Siguran?
There may be increased CNS depression when Siguran is administered concurrently with other CNS depressants, including alcohol, tranquilizers, and sedatives.
Based on in-vitro evaluation, Siguran is metabolized by CYP2D6. Therefore there is a possibility for a drug interaction between Siguran and CYP2D6 inhibitors.
Siguran side effects
See also:
What are the possible side effects of Siguran?
Applies to Siguran: oral capsule, oral tablet, oral tablet chewable
In addition to its needed effects, some unwanted effects may be caused by Siguran (the active ingredient contained in Siguran). In the event that any of these side effects do occur, they may require medical attention.
Major Side Effects
You should check with your doctor immediately if any of these side effects occur when taking Siguran:
Incidence not known:
- Cough
- difficulty swallowing
- dizziness
- drowsiness
- fast heartbeat
- hives
- itching
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- shortness of breath
- skin rash
- tightness in the chest
- unusual tiredness or weakness
Minor Side Effects
Some of the side effects that can occur with Siguran may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
Rare
- Blurred vision
- Dry mouth
- headache
Siguran contraindications
See also:
What is the most important information I should know about Siguran?
You should not take this medication if you are allergic to Siguran.
Before you take Siguran, tell your doctor if you have liver or kidney disease, asthma, glaucoma, an enlarged prostate, or urination problems.
This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Drinking alcohol can increase certain side effects of Siguran.
Cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by Siguran.
Active ingredient matches for Siguran:
List of Siguran substitutes (brand and generic names) | Sort by popularity |
Unit description / dosage (Manufacturer) | Price, USD |
Meclizine | |
Meclizine / Y.S. 25 mg | |
Meclizine / F.Y. 25 mg x 1000's | |
Meclizine tablet 12.5 mg/1 (DIRECT RX (US)) | |
Meclizine tablet 25 mg/1 (Contract Pharmacal Corp (US)) | |
Meclizine Chewable Tablets | |
Medi-Meclizine | |
Medivert | |
Meni-D | |
Monamine | |
Motion Sickness Relief | |
Motion Sickness Relief tablet 50 mg/1 (Better Living Brands, Llc (US)) | |
Motion Sickness Relief tablet 25 mg/1 (Target Corporation (US)) | |
Motion Sickness Relief tablet, chewable 25 mg/1 (WALGREEN CO. (US)) | |
Motion-Time | |
Neo-Istafene (Italy) | |
Neo-Suprimal | |
Neo-Suprimel | |
Nico-Vert (United States) | |
Parachloramine | |
Peremesin (Germany) | |
Peremesin N (Germany) | |
Dragee; Oral; Meclizine Hydrochloride (Bms) | |
Peremesine Suppositories | |
Suppositories; Rectal; Meclozine Hydrochloride | |
Postadoxin N (Germany) | |
Tablet; Oral; Meclizine Hydrochloride (Rodleben) | |
Ravelon | |
Ru-Vert-M | |
Sabari | |
Sea-Calm | |
Sea-calm tablet, chewable 25 mg/1 (Bellegrove (US)) | |
Simply Motion | |
Subari | |
Taizer | |
Travel Sickness | |
Tablet; Oral; Dimenhydrinate 50 mg (Cantassium co.) | |
Travel Sickness tablet 50 mg/1 (Cantassium co.) | |
Travel-Ease | |
Travel-ease tablet 25 mg/1 (Geri Care Pharmaceutical Corp (US)) | |
Travel-Ease Chewable Tablets | |
Travelon | |
V-Cline | |
Veritab | |
Verticalm | |
Verticalm tablet 25 mg/1 (Alva Amco Pharmacal Companies, Inc. (US)) | |
VOMINOS | |
VOMINOS 25 MG TABLET 1 strip / 10 tablets each (Colinz Laboratories Ltd) | $ 0.53 |
Vominos 25mg Tablet (Colinz Laboratories Ltd) | $ 0.05 |
Vomisseis | |
Vomissels | |
See 100 substitutes for Siguran |
References
- DailyMed. "MECLIZINE HYDROCHLORIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "meclizine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "meclizine". http://www.drugbank.ca/drugs/DB00737 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Siguran are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Siguran. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
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Information checked by Dr. Sachin Kumar, MD Pharmacology