Slo-Indo indications
Oral
Pain and inflammation associated with musculoskeletal and joint disorders
Adult: Initially, 25 mg bid or tid, increased if necessary by 25-50 mg at wkly intervals to 150-200 mg daily.
Oral
Acute gout
Adult: 150-200 mg daily in divided doses until signs and symptoms subside.
Oral
Dysmenorrhoea
Adult: 75 mg daily.
Intravenous
Closure of patent ductus arteriosus
Child: Given as 3 IV doses at 12-24 hr intervals infused over 20-30 min. Reconstitution: Add 1 or 2 mL of sterile water for inj or NaCl 0.9% inj to Slo-Indo 1 mg to provide soln containing approx 1 or 0.5 mg/mL respectively. Further dilution of the reconstituted inj in IV infusions is not recommended. Incompatibility: Y-site: Amino acid inj, Ca gluconate, cimetidine, dobutamine, dopamine, gentamicin, levofloxacin, pantoprazole, tobramycin. Inhibition of intraoperative miosis Adult: 4 drops 1 day pre-op and 4 drops 3 hr pre-op. Prophylaxis and reduction of postoperative ocular inflammation Adult: 1 drop 4-6 times daily. Post-photorefractive keratectomy pain Adult: 1 drop 4 times daily for a few days post-op. Pain and inflammation associated with musculoskeletal and joint disorders Adult: As supp: 100 mg to be inserted at night and repeated in the morning if necessary. A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Slo-Indo is considered an antioxidant. Pain and inflammation associated with musculoskeletal and joint disorders Adult: Initially, 25 mg bid or tid, increased if necessary by 25-50 mg at wkly intervals to 150-200 mg daily. Acute gout Adult: 150-200 mg daily in divided doses until signs and symptoms subside. Dysmenorrhoea Adult: 75 mg daily. Closure of patent ductus arteriosus Child: Given as 3 IV doses at 12-24 hr intervals infused over 20-30 min. Reconstitution: Add 1 or 2 mL of sterile water for inj or NaCl 0.9% inj to Slo-Indo 1 mg to provide soln containing approx 1 or 0.5 mg/mL respectively. Further dilution of the reconstituted inj in IV infusions is not recommended. Incompatibility: Y-site: Amino acid inj, Ca gluconate, cimetidine, dobutamine, dopamine, gentamicin, levofloxacin, pantoprazole, tobramycin. Inhibition of intraoperative miosis Adult: 4 drops 1 day pre-op and 4 drops 3 hr pre-op. Prophylaxis and reduction of postoperative ocular inflammation Adult: 1 drop 4-6 times daily. Post-photorefractive keratectomy pain Adult: 1 drop 4 times daily for a few days post-op. Pain and inflammation associated with musculoskeletal and joint disorders Adult: As supp: 100 mg to be inserted at night and repeated in the morning if necessary. May increase plasma levels of methotrexate. Increased risk of GI bleeding w/ warfarin. May reduce hypotensive effects of hydralazine, furosemide, β-blockers (e.g. atenolol, propranolol, oxprenolol), or thiazide diuretics. Increased risk of hyperkalaemia w/ K-sparing diuretics, ACE inhibitors, K supplements. May increase nephrotoxic effects of ciclosporin or triamterene. Increase plasma concentration w/ probenecid. May increase plasma levels of aminoglycoside (e.g. amikacin, gentamicin) in premature neonates. May enhance antipsychotic effect (e.g. severe drowsiness and confusion) of haloperidol. Al- or Mg-containing antacids may reduce GI disorders of Slo-Indo. Potentially Fatal: Diflunisal decreases renal clearance and increases plasma concentrations of Slo-Indo which leads to fatal GI haemorrhage. CHF, tachycardia, chest pain, arrhythmia, palpitations, HTN, pulmonary HTN, oedema; GI disturbances (e.g. nausea, vomiting, dyspepsia, indigestion, heartburn, epigastric pain); headache, frontal throbbing, apparent swelling of the temporal vessels, tinnitus, ataxia, tremor, dizziness, insomnia, vertigo, lightheadedness, confusion, psychiatric disturbances; haemolytic anaemia, bone marrow depression, agranulocytosis, leucopenia, thrombocytopenic purpura; corneal deposits and retinal disturbances, acute interstitial nephritis w/ haematuria, proteinuria, pruritus, urticaria, rash, macular and morbilliform eruptions, apnoea and exacerbation of pulmonary infection. Potentially Fatal: Anaphylactic reactions, Stevens-Johnson syndrome, toxic epidermal necrolysis, exfoliative dermatitis, aplastic anaemia, jaundice and fatal fulminant hepatitis, liver necrosis, hepatic failure, fulminant necrotising fasciitis, renal failure, MI, stroke, GI ulceration, perforation and haemorrhage. Known hypersensitivity to Slo-Indo, aspirin or other NSAIDs. Neonates w/ congenital heart disease when patency of the ductus arteriosus is needed for adequate pulmonary or systemic blood flow (e.g. neonates w/ pulmonary atresia, severe tetralogy of Fallot or severe coarctation of the aorta). Neonates w/ proven or suspected untreated infection, necrotising enterocolitis, impaired renal function, active bleeding (e.g. intraventricular haemorrhage or GI bleeding), thrombocytopenia or underlying coagulation defect. Patient w/ history of proctitis or recent rectal bleeding. History of asthma, urticaria, allergic-type reactions. Treatment of perioperative pain in the setting of CABG surgery. Concurrent use w/ diflunisal. Indometacin in United Kingdom. Information checked by Dr. Sachin Kumar, MD PharmacologyOphthalmic
Ophthalmic
Ophthalmic
Slo-Indo description
Slo-Indo dosage
Oral
Oral
Oral
Intravenous
Ophthalmic
Ophthalmic
Ophthalmic
Slo-Indo interactions
Slo-Indo side effects
Slo-Indo contraindications
Active ingredient matches for Slo-Indo:
List of Slo-Indo substitutes (brand and generic names)
Sort by popularity Unit description / dosage (Manufacturer) Price, USD Sandoz Indomethacin (South Africa) Suppositories; Rectal; Indometacin 50 mg Sandoz Indomethacin suppository 50 mg (Sandoz Canada Incorporated (Canada)) Sandoz Indomethacin suppository 100 mg (Sandoz Canada Incorporated (Canada)) Serastar (Japan) Servimeta (Bangladesh) Capsule; Oral; Indometacin 25 mg (Servipharm) Capsules; Oral; Indometacin 25 mg (Servipharm) Servindomet (Thailand) Sigadoc (Germany) Sinartril (Uruguay) Sinartril 100 (Uruguay) Sinartril 80 Retard (Uruguay)
Soltacina (Mexico) Capsule; Oral; Indometacin (Solara) Capsules; Oral; Indometacin (Solara) SPMC Indomethacin (Sri Lanka) Sportflex (Belgium) Sportflex 1% (Luxembourg) Stratasin (Mexico) Sulon (Taiwan) Sulon / L.S. 30 g Sulon / H.S.C. 7.5 mg/1 mL x 20 mL Tannex Tendinyl (Tunisia) Tenporal (Japan) Tenton (Taiwan) Tenton 25 mg x 1000's Teva-Indomethacin (Canada) Teva-indomethacin capsule 25 mg (Teva Canada Limited (Canada)) Teva-indomethacin capsule 50 mg (Teva Canada Limited (Canada)) Tofoanin (Taiwan) Tofoanin 25 mg TONFONYUANIN (Taiwan) TONFONYUANIN 25 mg Trap-On (Japan) Unguentum Indometacinum (Georgia) Uniof (Peru) Usan Vero-Indometacin Tablet, Film-Coated; Oral; Indometacin 25 mg Tablets, Film-Coated; Oral; Indometacin 25 mg Vi-Gel (Philippines) VI-Gel 1 % x 1.5 g (Diamond Lab) VI-Gel 1 % x 15 g (Diamond Lab) $ 3.33 VI-Gel cream 1% 15 g x 1's (Diamond Lab) $ 3.33 Vonum (Austria, Czech Republic) Vonum Cutan (Germany) Ointment; Topical; Indometacin 5% (Lichtenstein) Xantomicin Forte (Paraguay) Zempack (Japan) Zonema (Thailand) Zonema 25 mg x 1000's See 819 substitutes for Slo-Indo
Reviews
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Users % > 60 1 100.0%
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