What is Spasdel?
Spasdel produces many effects in the body, including relief from muscle spasms.
Spasdel also reduces the fluid secretions of many organs and glands in the body, such as the stomach, pancreas, lungs, saliva glands, sweat glands, and nasal passages.
Spasdel is used to treat many different stomach and intestinal disorders, including peptic ulcer and irritable bowel syndrome. It is also used to control muscle spasms in the bladder, kidneys, or digestive tract, and to reduce stomach acid. Spasdel is sometimes used to reduce tremors and rigid muscles in people with symptoms of Parkinson's disease.
Spasdel is also used as a drying agent to control excessive salivation, runny nose, or excessive sweating.
Spasdel may also be used for purposes not listed in this medication guide.
Spasdel indications
Spasdel® is effective as adjunctive therapy in the treatment of peptic ulcer. In acute episodes, Spasdel® injection can be used to control gastric secretion, visceral spasm and hypermotility in spastic colitis, spastic bladder, cystitis, pylorospasm, and associated abdominal cramps. For use as adjunctive therapy in the treatment of irritable bowel syndrome (irritable colon, spastic colon, mucous colitis) and functional gastrointestinal disorders. Also as adjunctive therapy in the treatment of neurogenic bladder and neurogenic bowel disturbances (including the splenic flexure syndrome and neurogenic colon).
Parenterally administered Spasdel® is also effective in reducing gastrointestinal motility to facilitate diagnostic procedures such as endoscopy or hypotonic duodenography. Spasdel® may be used to reduce pain and hypersecretion in pancreatitis, in certain cases of partial heart block associated with vagal activity, and as an antidote for poisoning by anticholinesterase agents.
- IN ANESTHESIA:
- Spasdel® injection is indicated as a pre-operative antimuscarinic to reduce salivary, tracheobronchial, and pharyngeal secretions, to reduce the volume and acidity of gastric secretions, and to block cardiac vagal inhibitory reflexes during induction of anesthesia and intubation. Spasdel® protects against the peripheral muscarinic effects such as bradycardia and excessive secretions produced by halogenated hydrocarbons and cholinergic agents such as physostigmine, neostigmine, and pyridostigmine given to reverse the actions of curariform agents.
- IN UROLOGY:
- Spasdel® injection may also be used intravenously to improve radiologic visibility of the kidneys. It is also indicated along with morphine or other narcotics in symptomatic relief of biliary and renal colic.
How should I use Spasdel?
Use Spasdel spray as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Spasdel spray. Talk to your pharmacist if you have questions about this information.
- Spasdel spray is usually taken 30 to 60 minutes before a meal. Follow your doctor's instructions for taking Spasdel spray.
- The spray pump must be primed before you use the first dose of Spasdel spray. Remove the plastic cover and point the opening away from yourself and others. Press down firmly and quickly until a fine mist appears (at least 3 sprays).
- To use Spasdel spray, hold the container upright. Open your mouth and bring the container as close as possible. Press down firmly and close your mouth. If necessary, repeat as directed by your doctor.
- Do not swallow immediately after you use the spray. Do not spit or rinse your mouth for 5 to 10 minutes after you use Spasdel spray.
- If you have not used the spray pump for 2 days or more, reprime before using it. Point the opening away from yourself and others and spray 1 time to reprime.
- Wipe the spray tip with a clean tissue and replace the cover.
- Do not use this bottle for more than 30 sprays even if it looks like it still contains medicine. The pump may not deliver the correct amount of medicine after 30 sprays.
- Do not take extra doses or stop using Spasdel spray without first checking with your doctor.
- If you also take antacids, take Spasdel spray before meals and the antacid after meals, unless directed otherwise by your doctor.
- If you miss a dose of Spasdel spray, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Spasdel spray.
Uses of Spasdel in details
Spasdel is used to treat a variety of stomach/intestinal problems such as cramps and irritable bowel syndrome. It is also used to treat other conditions such as bladder and bowel control problems, cramping pain caused by kidney stones and gallstones, and Parkinson's disease. In addition, it is used to decrease side effects of certain medications (drugs used to treat myasthenia gravis) and insecticides.
This medication works by decreasing acid production in the stomach, slowing down the natural movements of the gut, and relaxing muscles in many organs (e.g., stomach, intestines, bladder, kidney, gallbladder). Spasdel also lessens the amount of certain body fluids (e.g., saliva, sweat). This medication belongs to a class of drugs known as anticholinergics/antispasmodics.
How to use Spasdel sublingual
Place this medication under the tongue and allow it to dissolve. This medication may also be swallowed whole or chewed. It may be taken with or without meals. Take it as prescribed by your doctor.
Dosage is based on your medical condition and response to therapy. Do not increase your dose or take it more often than prescribed without consulting your doctor. Adults and children 12 years and older should not take more than 1.5 milligrams in 24 hours. Children aged 2 to 12 years should not take more than 0.75 milligrams in 24 hours. Ask your doctor or pharmacist for more information.
Antacids lower the absorption of Spasdel. If you use antacids, take them after meals and take Spasdel before meals; or take antacids at least 1 hour after taking Spasdel.
Drink plenty of fluids while taking this medication unless your doctor directs you otherwise.
Inform your doctor if your condition persists or worsens.
Spasdel description
Spasdel is a chemical compound, a tropane alkaloid it is the levo-isomer to atropine. It is a secondary metabolite of some plants, particularly henbane (Hyoscamus niger.) Spasdel is used to provide symptomatic relief to various gastrointestinal disorders including spasms, peptic ulcers, irritable bowel syndrome, pancreatitis, colic and cystitis. It has also been used to relieve some heart problems, control some of the symptoms of Parkinson's disease, as well as for control of respiratory secretions in end of life care.
Spasdel dosage
Spasdel Dosage
Generic name: Spasdel SULFATE.125mg
Dosage form: tablet
See also:
- Spasdel-DT tablet
- Spasdel-FT Chewable Melt tablet
- Spasdel-SL tablet
- Spasdel-SR tablet
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Usual adult and adolescent dose: 1 to 2 tablets three or four times a day, thirty minutes to one hour before meals and at bedtime, the dosage being adjusted as needed and tolerated.
Note: Geriatric patients may be more sensitive to the effects of the usual adult dose.
Usual dose for children 6 to under 12 years of age: 1/2 to 1 tablet three or four times a day, thirty minutes to one hour before meals and at bedtime. Dosage should be individualized by physician according to patient’s needsand tolerance
Note: This product is not recommended for use in children under six years of age.
More about Spasdel (Spasdel)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
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- En Espanol
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Consumer resources
- Spasdel
- Other brands: Spasdel, Spasdel, Spasdel, Spasdel, More (15) »
Professional resources
- Spasdel (FDA)
- Spasdel Sulfate (AHFS Monograph)
Other formulations
- Spasdel SL
- Spasdel FT
- Spasdel SR
- More (1) »
Related treatment guides
- Anesthesia
- Crohn's Disease
- Endoscopy or Radiology Premedication
- Irritable Bowel Syndrome
- Urinary Incontinence
Spasdel interactions
See also:
What other drugs will affect Spasdel?
Additive adverse effects resulting from cholinergic blockade may occur when Spasdel® (Spasdel) is administered concomitantly with other antimuscarinics, amantadine, haloperidol, phenothiazines, monoamine oxidase (MAO) inhibitors, tricyclic antidepressants or some antihistamines.
Antacids may interfere with the absorption of Spasdel® (Spasdel). Administer Spasdel® (Spasdel) before meals; antacids after meals.
Spasdel side effects
See also:
What are the possible side effects of Spasdel?
Applies to Spasdel: oral conventional tablets and sublingual tablets, oral extended-release capsules and tablets, oral oral solution and elixir, oral orally disintegrating tablets, parenteral injection
Side effects include:
Most adverse effects are manifestations of pharmacologic effects at muscarinic-cholinergic receptors and usually are reversible when therapy is discontinued.
Severity and frequency of adverse effects are dose related and individual intolerance varies greatly; adverse effects occasionally may be obviated by a reduction in dosage but this also may eliminate potential therapeutic effects.
Adverse effects include dry mouth, urinary hesitancy and retention, blurred vision, tachycardia, palpitations, mydriasis, increased ocular tension, loss of taste, headache, nervousness, drowsiness, weakness, fatigue, dizziness, insomnia, nausea, vomiting, impotence, constipation, bloated feeling, abdominal pain, diarrhea, allergic reactions or drug idiosyncrasies, urticaria and other dermal manifestations, ataxia, speech disturbance, mental confusion and/or excitement (especially in geriatric patients), short-term memory loss, hallucinations, and decreased sweating.
Spasdel contraindications
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What is the most important information I should know about Spasdel?
Do not take Spasdel if you are allergic to it, or if you have kidney disease, a bladder or intestinal obstruction, severe ulcerative colitis, toxic megacolon, glaucoma, or myasthenia gravis.
Before taking Spasdel, tell your doctor if you have heart disease, congestive heart failure, a heart rhythm disorder, high blood pressure, overactive thyroid, or hiatal hernia with gastroesophageal reflux disease.
Avoid taking antacids at the same time you take Spasdel. Antacids can make it harder for your body to absorb Spasdel. If you use an antacid, take it after you have taken Spasdel and eaten a meal.
Spasdel may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Drinking alcohol can increase drowsiness and dizziness while you are taking Spasdel.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Spasdel can decrease sweating and you may be more prone to heat stroke.
Active ingredient matches for Spasdel:
List of Spasdel substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Nuspas (Taiwan) | |
| Nuspas 100+10 Tablet (Bioman Pharmaceuticals) | $ 0.03 |
| NUSPAS 20MG/100MG TABLET 1 strip / 10 tablets each (Bioman Pharmaceuticals) | $ 0.18 |
| Nuspas Tablet (Bioman Pharmaceuticals) | $ 0.02 |
| Oin | |
| Oin 500 mg Injection (Odin Healthcare Pvt Ltd) | $ 0.58 |
| Oin 100 mg Injection (Odin Healthcare Pvt Ltd) | $ 0.23 |
| Oin 250 mg Injection (Odin Healthcare Pvt Ltd) | $ 0.42 |
| Oscimin | |
| Oscimin tablet, orally disintegrating .125 mg/1 (Larken Laboratories, Inc. (US)) | |
| Oscimin tablet, extended release .375 mg/1 (Larken Laboratories, Inc. (US)) | |
| Oscimin tablet .125 mg/1 (Larken Laboratories, Inc. (US)) | |
| Oscimin Oral Dispersible Tablet | |
| Oscimin SR | |
| Oscimin SR Tablets | |
| Peptard (India) | |
| 20 mg x 10's (Indchemie) | $ 0.54 |
| Peptard 20mg TAB / 10 (Indchemie) | $ 0.54 |
| PEPTARD 10 MG TABLET 1 strip / 10 tablets each (Indchemie) | $ 0.34 |
| PEPTARD 20 MG INJECTION 1 vial / 1 injection each (Indchemie) | $ 0.86 |
| PEPTARD 20 MG TABLET 1 strip / 10 tablets each (Indchemie) | $ 1.07 |
| PEPTARD tab 20 mg x 10's (Indchemie) | $ 0.98 |
| Peptard 10mg Tablet (Indchemie) | $ 0.03 |
| Peptard 20mg Injection (Indchemie) | $ 0.86 |
| Peptard 20mg Tablet (Indchemie) | $ 0.12 |
| Powecon (Taiwan) | |
| Powecon 0.125 mg | |
| Scopolaminum | |
| Drops; Oral; Hyoscyamine Hydrobromide 6 x | |
| Globules; Oral; Hyoscyamine Hydrobromide 6 x | |
| Granules; Oral; Hyoscyamine Hydrobromide 6 x | |
| Tablet; Oral; Scopolamine Hydrobromide 6 ch | |
| Scopolia Extract | |
| Spalytic (Taiwan) | |
| Spalytic 0.125 mg | |
| Spasdel Drops | |
| Spasdel Elixir | |
| Spazaway (Egypt) | |
| Symax (United States) | |
| Symax Duotab | |
| Symax Duotab tablet, multilayer, extended release .375 mg/1 (Capellon Pharmaceuticals, LLC (US)) | |
| Symax Duotab Controlled-Release Tablets | |
| Symax FasTab | |
| Symax Fastab tablet, orally disintegrating .125 mg/1 (Capellon Pharmaceuticals, LLC (US)) | |
| Symax FasTabs | |
| Symax FasTabs Orally Disintegrating Tablets | |
| Symax SR | |
| Symax SR tablet, extended release .375 mg/1 (Capellon Pharmaceuticals, LLC (US)) | |
| Symax SR Extended-Release Tablets | |
| Symax-SL | |
| Symax-SR | |
See 164 substitutes for Spasdel | |
References
- PubChem. "hyoscyamine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "hyoscyamine". http://www.drugbank.ca/drugs/DB00424 (accessed September 17, 2018).
- MeSH. "Parasympatholytics". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Spasdel are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Spasdel. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
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Information checked by Dr. Sachin Kumar, MD Pharmacology
