What is T Press AM?
T Press AM is used alone or together with other medicines to treat angina (chest pain) and high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.
T Press AM is a calcium channel blocker. It affects the movement of calcium into the cells of the heart and blood vessels. As a result, T Press AM relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.
T Press AM is available only with your doctor's prescription.
T Press AM indications
Hypertension: T Press AM is indicated for the first-line treatment of hypertension and can be used as the sole agent to control blood pressure in the majority of patients. Patients not adequately controlled on a single antihypertensive agent may benefit from the addition of T Press AM, which has been used in combination with a thiazide diuretic, β-adrenoceptor-blocking agent or an angiotensin-converting enzyme inhibitor.
T Press AM is also indicated to reduce the risk of fatal coronary heart disease (CHD) and non-fatal myocardial infarction (MI), and to reduce the risk of stroke.
Coronary Artery Disease: T Press AM is indicated to reduce the risk of coronary revascularization and the need for hospitalization due to angina in patients with coronary artery disease (CAD).
Chronic Stable Angina: T Press AM is indicated for the first-line treatment of myocardial ischemia, whether due to fixed obstruction (stable angina) and/or vasospasm/vasoconstriction (Prinzmetal’s or variant angina) of coronary vasculature. T Press AM may be used where the clinical presentation suggests a possible vasospastic/vasoconstrictive component but where vasospasm/vasoconstriction has not been confirmed. T Press AM may be used alone, as monotherapy, or in combination with other antianginal drugs in patients with angina that is refractory to nitrates and/or adequate doses of beta-blockers.
How should I use T Press AM?
Use T Press AM as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with T Press AM. Talk to your pharmacist if you have questions about this information.
- Take T Press AM by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
- Taking T Press AM at the same time each day will help you remember to take it.
- Continue to take T Press AM even if you feel well. Do not miss any doses.
- If you miss a dose of T Press AM, take it as soon as possible. If it has been more than 12 hours since you missed your last dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use T Press AM.
Uses of T Press AM in details
This medication is used along with other treatment for certain blood vessel diseases (e.g., arteriosclerosis obliterans, Raynaud's disease, Buerger's disease, cerebrovascular insufficiency). It works by widening blood vessels to help increase blood flow (improve circulation) to certain parts of the body (e.g., hands/feet, brain). This effect may help to decrease symptoms such as cold hands and feet, numbness, tingling, and decreased memory or judgment.
How to use T Press AM
This medication is taken by mouth with or without food, usually 3 to 4 times daily or as directed by your doctor. Dosage is based on your medical condition and response to treatment.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.
Tell your doctor if your condition persists or worsens.
T Press AM description
Each 5-mg and 10-mg tablet contains Amlodipine besilate equivalent to T Press AM 5 mg and 10 mg, respectively.
T Press AM also contains the following excipients: Calcium hydrogen phosphate anhydrous, microcrystalline cellulose, magnesium stearate, sodium starch glycollate.
T Press AM besilate is the besilate salt of T Press AM, a long-acting calcium-channel blocker. It is 3-ethyl-5-methyl-2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate benzenesulphonate. Its empirical formula is C20H25ClN2O5·C6H6O3S and has a molecular weight of 567.1.
T Press AM besilate is a white crystalline powder and is slightly soluble in water and sparingly soluble in ethanol.
T Press AM dosage
For both hypertension and angina, the usual initial dose is 5 mg T Press AM once daily, which may be increased to a maximum dose of 10 mg depending on the individual patient's response.
For patients with coronary artery disease, the recommended dosage range is 5 mg to 10 mg once daily. In clinical studies, the majority of patients required 10 mg once daily.
No dose adjustment of T Press AM is required upon concomitant administration of thiazide diuretics, beta-blockers, and ACE inhibitors.
T Press AM ODT: For T Press AM orodispersible tablets, the patient should place the tablet on the tongue and allow it to dissolve.
Elderly: Normal dosage regimens are recommended. T Press AM, used at similar doses in the elderly or younger patients, is equally well-tolerated.
Children: Safety and effectiveness of T Press AM in children have not been established.
Patients with Impaired Hepatic Function: See Precautions.
Patients with Renal Failure: T Press AM may be used at normal doses in patients with renal failure.
Changes in T Press AM plasma concentrations are not correlated with the degree of renal impairment. T Press AM is not dialyzable.
T Press AM interactions
See also:
What other drugs will affect T Press AM?
In vitro data in human plasma indicate that T Press AM has no effect on the protein-binding of drugs tested (digoxin, phenytoin, warfarin and indomethacin).
Special Studies: Effect of Other Agents on T Press AM:
Cimetidine: Co-administration of T Press AM with cimetidine did not alter the pharmacokinetics of T Press AM.
Grapefruit Juice: Co-administration of 240 mL of grapefruit juice with a single oral dose of T Press AM 10 mg in 20 healthy volunteers had no significant effect on the pharmacokinetics of T Press AM.
Antacid: Co-administration of antacid with a single dose of T Press AM had no significant effect on the pharmacokinetics of T Press AM.
Sildenafil: A single 100-mg dose of sildenafil in subjects with essential hypertension had no effect on the pharmacokinetic parameters of T Press AM. When T Press AM and sildenafil were used in combination, each agent independently exerted its own blood pressure-lowering effect.
Effect of T Press AM on Other Agents: Atorvastatin: Co-administration of multiple 10-mg doses of T Press AM with 80 mg of atorvastatin resulted in no significant change in the steady-state pharmacokinetic parameters of atorvastatin.
Digoxin: Co-administration of T Press AM with digoxin did not change serum digoxin levels or digoxin renal clearance in normal volunteers.
Ethanol (alcohol): Single and multiple 10-mg doses of T Press AM had no significant effect on the pharmacokinetics of ethanol.
Warfarin: Co-administration of T Press AM with warfarin did not change the warfarin prothrombin response time.
In clinical trials, T Press AM has been safely administered with thiazide diuretics, β-blockers, ACE inhibitors, long-acting nitrates, sublingual nitroglycerin, digoxin, warfarin, NSAIDs, antibiotics and oral hypoglycemic drugs.
Drug/Laboratory Test Interactions: None known.
T Press AM side effects
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What are the possible side effects of T Press AM?
The most common adverse effects of T Press AM besilate, similar to that of other calcium-channel blockers, are associated with its vasodilating effects are often lessened with continued use of the drug. Among them are flushing, headache disorders, dizziness and peripheral edema, the most common of which are edema and flushing which are due to the vasodilating effect of T Press AM.
Abdominal pain with cramps, fatigue, palpitations, tachycardia and nausea are less frequently experienced with the use of T Press AM.
Other adverse effects associated with the use of T Press AM include increased micturition, eye pain and other visual disturbances, mental or mood changes eg, depression, anxiety or nervousness, decreased sexual ability/desire, constipation and fainting.
At the start of the treatment, a paradoxical increase in ischemic chest pain may be experienced. In some patients, cerebral or myocardial ischemia or transient blindness caused by excessive fall in blood pressure occur. T Press AM, in 1 study was found to induce gingival overgrowth.
Hypersensitivity reactions to T Press AM may occur leading to rashes, including erythema multiforme, fever and abnormal liver functions eg, cholestasis. Other symptoms of allergic reactions are itching, swelling, severe dizziness and trouble breathing.
T Press AM contraindications
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What is the most important information I should know about T Press AM?
Before taking T Press AM, tell your doctor if you have congestive heart failure or liver disease.
Drinking alcohol can further lower your blood pressure and may increase certain side effects of T Press AM.
If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
T Press AM is only part of a complete program of treatment that may also include diet, exercise, weight control, and other medications. Follow your diet, medication, and exercise routines very closely.
Tell your doctor about all other heart or blood pressure medications you are taking.
Your chest pain may become worse when you first start taking T Press AM or when your dose is increased. Call your doctor if your chest pain is severe or ongoing.
Active ingredient matches for T Press AM:
| Unit description / dosage (Manufacturer) | Price, USD |
| T Press AM 40+5 Tablet | $ 0.08 |
List of T Press AM substitutes (brand and generic names): | |
| Systonorm AT | |
| Systonorm AT 5 mg/50 mg Tablet (Acron Pharmaceuticals) | $ 0.02 |
| Tai Guk Amlodipine (South Korea) | |
| Tamlod (India) | |
| Tamlod 5mg TAB / 10 (Merind Ltd (Wockhardt Ltd)) | $ 0.34 |
| Tamlod 10mg TAB / 10 (Merind Ltd (Wockhardt Ltd)) | $ 0.57 |
| Tamlod 10 mg Tablet (Merind Ltd (Wockhardt Ltd)) | $ 0.06 |
| Tamlod 5 mg Tablet (Merind Ltd (Wockhardt Ltd)) | $ 0.03 |
| TAMLOD tab 5 mg x 10's (Merind Ltd (Wockhardt Ltd)) | $ 0.34 |
| TAMLOD tab 10 mg x 10's (Merind Ltd (Wockhardt Ltd)) | $ 0.57 |
| Tamlod 10mg Tablet (Merind Ltd (Wockhardt Ltd)) | $ 0.06 |
| Tamlod 5mg Tablet (Merind Ltd (Wockhardt Ltd)) | $ 0.03 |
| Tamlod AT 5mg/50mg Tablet (Merind Ltd (Wockhardt Ltd)) | $ 0.05 |
| Tardip (Romania) | |
| Targit AM | |
| Targit AM 40+5 Tablet (Pfizer Limited (Pharmacia India Pvt Ltd)) | $ 0.10 |
| TARGIT AM 40 MG TABLET 1 strip / 15 tablets each (Pfizer Limited (Pharmacia India Pvt Ltd)) | $ 1.91 |
| TARGIT AM 80 MG TABLET 1 strip / 15 tablets each (Pfizer Limited (Pharmacia India Pvt Ltd)) | $ 2.00 |
| Tazloc AM | |
| Tazloc AM 40+5 Tablet (USV Limited.) | $ 0.08 |
| TAZLOC AM 40 TABLET 1 strip / 10 tablets each (USV Limited.) | $ 1.14 |
| TAZLOC AM 80 MG TABLET 1 strip / 10 tablets each (USV Limited.) | $ 1.90 |
| Tazloc Trio | |
| Tazloc Trio 40+5 Tablet (USV Limited.) | $ 0.11 |
| TAZLOC TRIO 40 MG TABLET 1 strip / 10 tablets each (USV Limited.) | $ 1.31 |
| TAZLOC TRIO 80 MG TABLET 1 strip / 10 tablets each (USV Limited.) | $ 1.90 |
| Tazloc Trio 40 Tablet (USV Limited.) | $ 0.13 |
| Tazloc Trio 80 Tablet (USV Limited.) | $ 0.19 |
| Telar-AM (India) | |
| Telar-AM Telmisartan 40 mg, Amlodipine5 mg. TAB / 10 (Medley (Vazokare)) | $ 0.82 |
| 10's (Medley (Vazokare)) | $ 0.82 |
| Telar-AM Telmisartan 40mg, Amlodipine5mg TAB / 10 (Medley (Vazokare)) | $ 0.82 |
| TELAR-AM tab 10's (Medley (Vazokare)) | $ 0.82 |
| Teleact AM | |
| Teleact AM 80+5 Tablet (Ranbaxy Laboratories Ltd.,) | $ 0.14 |
| Teleact AM 40+5 Tablet (Ranbaxy Laboratories Ltd.,) | $ 0.09 |
| TELEACT AM 40 MG TABLET 1 strip / 10 tablets each (Ranbaxy Laboratories Ltd.,) | $ 1.19 |
| TELEACT AM 80 MG TABLET 1 strip / 10 tablets each (Ranbaxy Laboratories Ltd.,) | $ 1.72 |
| Teleact AM 40 mg Tablet (Ranbaxy Laboratories Ltd.,) | $ 0.13 |
| Teli AM | |
| Teli AM 80+5 Tablet (Cadila Pharmaceuticals Ltd.) | $ 0.13 |
| TELI AM 80 MG TABLET 1 strip / 10 tablets each (Cadila Pharmaceuticals Ltd.) | $ 1.31 |
| Teli AM 80 mg Tablet (Cadila Pharmaceuticals Ltd.) | $ 0.13 |
| Telista AM | |
| Telista AM 5+50 Tablet (Lupin Laboratories Ltd.) | $ 0.10 |
| Telista AM 2.5+40 Tablet (Lupin Laboratories Ltd.) | $ 0.09 |
| TELISTA AM 40 MG TABLET 1 strip / 15 tablets each (Lupin Laboratories Ltd.) | $ 1.97 |
| TELISTA AM 80 MG TABLET 1 strip / 10 tablets each (Lupin Laboratories Ltd.) | $ 2.30 |
| Telma AM H | |
| Telma AM H 80+5+12.5 Tablet (Glenmark Pharmaceuticals Ltd.) | $ 0.18 |
| Telma AM H 40+5+12.5 Tablet (Glenmark Pharmaceuticals Ltd.) | $ 0.12 |
| Telmikind AM | |
| Telmikind AM 40+5 Tablet (Mankind Pharmaceuticals Pvt. Ltd.) | $ 0.04 |
See 4039 substitutes for T Press AM | |
References
- PubChem. "amlodipine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "amlodipine". http://www.drugbank.ca/drugs/DB00381 (accessed September 17, 2018).
- MeSH. "Antihypertensive Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for T Press AM are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking T Press AM. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
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Information checked by Dr. Sachin Kumar, MD Pharmacology
