What is Telar-AM?
Telar-AM is used alone or together with other medicines to treat angina (chest pain) and high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.
Telar-AM is a calcium channel blocker. It affects the movement of calcium into the cells of the heart and blood vessels. As a result, Telar-AM relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.
Telar-AM is available only with your doctor's prescription.
Telar-AM indications
Hypertension: Telar-AM is indicated for the first-line treatment of hypertension and can be used as the sole agent to control blood pressure in the majority of patients. Patients not adequately controlled on a single antihypertensive agent may benefit from the addition of Telar-AM, which has been used in combination with a thiazide diuretic, β-adrenoceptor-blocking agent or an angiotensin-converting enzyme inhibitor.
Telar-AM is also indicated to reduce the risk of fatal coronary heart disease (CHD) and non-fatal myocardial infarction (MI), and to reduce the risk of stroke.
Coronary Artery Disease: Telar-AM is indicated to reduce the risk of coronary revascularization and the need for hospitalization due to angina in patients with coronary artery disease (CAD).
Chronic Stable Angina: Telar-AM is indicated for the first-line treatment of myocardial ischemia, whether due to fixed obstruction (stable angina) and/or vasospasm/vasoconstriction (Prinzmetal’s or variant angina) of coronary vasculature. Telar-AM may be used where the clinical presentation suggests a possible vasospastic/vasoconstrictive component but where vasospasm/vasoconstriction has not been confirmed. Telar-AM may be used alone, as monotherapy, or in combination with other antianginal drugs in patients with angina that is refractory to nitrates and/or adequate doses of beta-blockers.
How should I use Telar-AM?
Use Telar-AM as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Telar-AM. Talk to your pharmacist if you have questions about this information.
- Take Telar-AM by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
- Taking Telar-AM at the same time each day will help you remember to take it.
- Continue to take Telar-AM even if you feel well. Do not miss any doses.
- If you miss a dose of Telar-AM, take it as soon as possible. If it has been more than 12 hours since you missed your last dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Telar-AM.
Uses of Telar-AM in details
This medication is used along with other treatment for certain blood vessel diseases (e.g., arteriosclerosis obliterans, Raynaud's disease, Buerger's disease, cerebrovascular insufficiency). It works by widening blood vessels to help increase blood flow (improve circulation) to certain parts of the body (e.g., hands/feet, brain). This effect may help to decrease symptoms such as cold hands and feet, numbness, tingling, and decreased memory or judgment.
How to use Telar-AM
This medication is taken by mouth with or without food, usually 3 to 4 times daily or as directed by your doctor. Dosage is based on your medical condition and response to treatment.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.
Tell your doctor if your condition persists or worsens.
Telar-AM description
Each 5-mg and 10-mg tablet contains Amlodipine besilate equivalent to Telar-AM 5 mg and 10 mg, respectively.
Telar-AM also contains the following excipients: Calcium hydrogen phosphate anhydrous, microcrystalline cellulose, magnesium stearate, sodium starch glycollate.
Telar-AM besilate is the besilate salt of Telar-AM, a long-acting calcium-channel blocker. It is 3-ethyl-5-methyl-2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate benzenesulphonate. Its empirical formula is C20H25ClN2O5·C6H6O3S and has a molecular weight of 567.1.
Telar-AM besilate is a white crystalline powder and is slightly soluble in water and sparingly soluble in ethanol.
Telar-AM dosage
For both hypertension and angina, the usual initial dose is 5 mg Telar-AM once daily, which may be increased to a maximum dose of 10 mg depending on the individual patient's response.
For patients with coronary artery disease, the recommended dosage range is 5 mg to 10 mg once daily. In clinical studies, the majority of patients required 10 mg once daily.
No dose adjustment of Telar-AM is required upon concomitant administration of thiazide diuretics, beta-blockers, and ACE inhibitors.
Telar-AM ODT: For Telar-AM orodispersible tablets, the patient should place the tablet on the tongue and allow it to dissolve.
Elderly: Normal dosage regimens are recommended. Telar-AM, used at similar doses in the elderly or younger patients, is equally well-tolerated.
Children: Safety and effectiveness of Telar-AM in children have not been established.
Patients with Impaired Hepatic Function: See Precautions.
Patients with Renal Failure: Telar-AM may be used at normal doses in patients with renal failure.
Changes in Telar-AM plasma concentrations are not correlated with the degree of renal impairment. Telar-AM is not dialyzable.
Telar-AM interactions
See also:
What other drugs will affect Telar-AM?
In vitro data in human plasma indicate that Telar-AM has no effect on the protein-binding of drugs tested (digoxin, phenytoin, warfarin and indomethacin).
Special Studies: Effect of Other Agents on Telar-AM:
Cimetidine: Co-administration of Telar-AM with cimetidine did not alter the pharmacokinetics of Telar-AM.
Grapefruit Juice: Co-administration of 240 mL of grapefruit juice with a single oral dose of Telar-AM 10 mg in 20 healthy volunteers had no significant effect on the pharmacokinetics of Telar-AM.
Antacid: Co-administration of antacid with a single dose of Telar-AM had no significant effect on the pharmacokinetics of Telar-AM.
Sildenafil: A single 100-mg dose of sildenafil in subjects with essential hypertension had no effect on the pharmacokinetic parameters of Telar-AM. When Telar-AM and sildenafil were used in combination, each agent independently exerted its own blood pressure-lowering effect.
Effect of Telar-AM on Other Agents: Atorvastatin: Co-administration of multiple 10-mg doses of Telar-AM with 80 mg of atorvastatin resulted in no significant change in the steady-state pharmacokinetic parameters of atorvastatin.
Digoxin: Co-administration of Telar-AM with digoxin did not change serum digoxin levels or digoxin renal clearance in normal volunteers.
Ethanol (alcohol): Single and multiple 10-mg doses of Telar-AM had no significant effect on the pharmacokinetics of ethanol.
Warfarin: Co-administration of Telar-AM with warfarin did not change the warfarin prothrombin response time.
In clinical trials, Telar-AM has been safely administered with thiazide diuretics, β-blockers, ACE inhibitors, long-acting nitrates, sublingual nitroglycerin, digoxin, warfarin, NSAIDs, antibiotics and oral hypoglycemic drugs.
Drug/Laboratory Test Interactions: None known.
Telar-AM side effects
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What are the possible side effects of Telar-AM?
The most common adverse effects of Telar-AM besilate, similar to that of other calcium-channel blockers, are associated with its vasodilating effects are often lessened with continued use of the drug. Among them are flushing, headache disorders, dizziness and peripheral edema, the most common of which are edema and flushing which are due to the vasodilating effect of Telar-AM.
Abdominal pain with cramps, fatigue, palpitations, tachycardia and nausea are less frequently experienced with the use of Telar-AM.
Other adverse effects associated with the use of Telar-AM include increased micturition, eye pain and other visual disturbances, mental or mood changes eg, depression, anxiety or nervousness, decreased sexual ability/desire, constipation and fainting.
At the start of the treatment, a paradoxical increase in ischemic chest pain may be experienced. In some patients, cerebral or myocardial ischemia or transient blindness caused by excessive fall in blood pressure occur. Telar-AM, in 1 study was found to induce gingival overgrowth.
Hypersensitivity reactions to Telar-AM may occur leading to rashes, including erythema multiforme, fever and abnormal liver functions eg, cholestasis. Other symptoms of allergic reactions are itching, swelling, severe dizziness and trouble breathing.
Telar-AM contraindications
See also:
What is the most important information I should know about Telar-AM?
Before taking Telar-AM, tell your doctor if you have congestive heart failure or liver disease.
Drinking alcohol can further lower your blood pressure and may increase certain side effects of Telar-AM.
If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
Telar-AM is only part of a complete program of treatment that may also include diet, exercise, weight control, and other medications. Follow your diet, medication, and exercise routines very closely.
Tell your doctor about all other heart or blood pressure medications you are taking.
Your chest pain may become worse when you first start taking Telar-AM or when your dose is increased. Call your doctor if your chest pain is severe or ongoing.
Active ingredient matches for Telar-AM:
Amlodipine in India.
Telmisartan in India.
| Unit description / dosage (Manufacturer) | Price, USD |
| Telar-AM Telmisartan 40 mg, Amlodipine5 mg. TAB / 10 | $ 0.82 |
| 10's | $ 0.82 |
| Telar-AM Telmisartan 40mg, Amlodipine5mg TAB / 10 | $ 0.82 |
| TELAR-AM tab 10's (Medley (Vazokare)) | $ 0.82 |
List of Telar-AM substitutes (brand and generic names): | |
| Telar- H | |
| Telar- H Telmisartan 40mg, Hydrochlorothiazide 12.5mg TAB / 10 | $ 0.83 |
| Telart (Vietnam) | |
| Telart HCT 2 Blister x 7 Tablet | |
| Telart 20 mg x 2 Blister x 7 Tablet | |
| Telart 40 mg x 2 Blister x 7 Tablet | |
| Telart 80 mg x 2 Blister x 7 Tablet | |
| Telartan (Georgia) | |
| Telarteq (Mexico) | |
| TELAST | |
| TELAST 20 MG TABLET 1 strip / 7 tablets each (Intas Pharmaceuticals Ltd) | $ 0.30 |
| TELAST 40 MG TABLET 1 strip / 7 tablets each (Intas Pharmaceuticals Ltd) | $ 0.54 |
| TELAST 80 MG TABLET 1 strip / 7 tablets each (Intas Pharmaceuticals Ltd) | $ 0.83 |
| Telast 20mg Tablet (Intas Pharmaceuticals Ltd) | $ 0.04 |
| Telast 40mg Tablet (Intas Pharmaceuticals Ltd) | $ 0.08 |
| Telast 80mg Tablet (Intas Pharmaceuticals Ltd) | $ 0.12 |
| Telast CT 40mg/12.5mg Tablet (Intas Pharmaceuticals Ltd) | $ 0.13 |
| Telast CT 80 Tablet (Intas Pharmaceuticals Ltd) | $ 0.18 |
| TELAT | |
| TELAT 40MG TABLET 1 strip / 10 tablets each (Apostle Remedies) | $ 0.46 |
| Telben | |
| Telben 40mg Tablet (R B Pharmaceuticals) | $ 0.08 |
| Telblok (India) | |
| Telblok 40 mg Tablet (Shreya Life Sciences Pvt. Ltd) | $ 0.09 |
| Telblok 20 mg Tablet (Shreya Life Sciences Pvt. Ltd) | $ 0.04 |
| TELBLOK 20 MG TABLET 1 strip / 10 tablets each (Shreya Life Sciences Pvt. Ltd) | $ 0.58 |
| TELBLOK 40 MG TABLET 1 strip / 10 tablets each (Shreya Life Sciences Pvt. Ltd) | $ 1.00 |
| TELBLOK tab 40 mg x 10's (Shreya Life Sciences Pvt. Ltd) | $ 1.01 |
| Telblok 20mg Tablet (Shreya Life Sciences Pvt. Ltd) | $ 0.04 |
| Telblok 40mg Tablet (Shreya Life Sciences Pvt. Ltd) | $ 0.08 |
| Telblok H | |
| Telblok H 40+12.5 Tablet (Shreya Life Sciences Pvt. Ltd) | $ 0.09 |
| TELBLOK H TABLET 1 strip / 10 tablets each (Shreya Life Sciences Pvt. Ltd) | $ 1.26 |
| Telblok H Tablet (Shreya Life Sciences Pvt. Ltd) | $ 0.14 |
| TELBRIT | |
| Telbrit 20mg Tablet (Elbrit LIfe Sciences) | $ 0.04 |
| Telbrit 40mg Tablet (Elbrit LIfe Sciences) | $ 0.10 |
| TELBRIT CT 40MG/12.5MG TABLET (Elbrit LIfe Sciences) | $ 0.10 |
| TELBRIT H 40MG/12.5MG TABLET (Elbrit LIfe Sciences) | $ 0.10 |
| Telcard (Myanmar) | |
| Telcard 40 mg Tablet (Vivid Biotek Pvt. Ltd.) | $ 0.10 |
| Telcard 80 mg Tablet (Vivid Biotek Pvt. Ltd.) | $ 0.15 |
| TELCROS | |
| TELCROS 40 MG TABLET 1 strip / 10 tablets each (Gold Line) | $ 0.84 |
| TELCROS 80 MG TABLET 1 strip / 10 tablets each (Gold Line) | $ 1.02 |
| Telcros 40mg Tablet (Gold Line) | $ 0.08 |
| Telcros 80mg Tablet (Gold Line) | $ 0.10 |
| TELCROS CT 40MG/12.5MG TABLET (Gold Line) | $ 0.11 |
| Telcure (India) | |
| Telcure 40mg TAB / 15 (Impact) | |
| TELCURE 20 MG TABLET 1 strip / 10 tablets each (Impact) | $ 0.40 |
| TELCURE 40 MG TABLET 1 strip / 10 tablets each (Impact) | $ 0.79 |
| TELCURE 80MG TABLET 1 strip / 10 tablets each (Impact) | $ 1.19 |
See 5830 substitutes for Telar-AM | |
References
- DailyMed. "AMLODIPINE BESYLATE; TELMISARTAN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "Telmisartan". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- PubChem. "amlodipine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Telar-AM are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Telar-AM. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
