Thelmex Uses

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What is Thelmex?

Thelmex belongs to the family of medicines called anthelmintics. Anthelmintics are used in the treatment of worm infections.

Thelmex is used to treat pinworms (enterobiasis; oxyuriasis).

Thelmex may also be used for other worm infections as determined by your doctor.

Thelmex works by paralyzing the worms. They are then passed in the stool.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, Thelmex is used in certain patients with the following medical condition:

For patients taking Thelmex for hookworm infection :

Thelmex indications

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Oral

Single or mixed infections due to susceptible worms

Adult: 10 mg/kg as a single dose.

Child: 10 mg/kg as a single dose.

Oral

Ascariasis

Adult: 5 mg/kg as a single dose. Max: 1 g/dose. For mass treatment programmes: 2.5 mg/kg as a single dose given 3-4 times a yr.

Oral

Necatoriasis

Adult: 10 mg/kg daily for 3-4 days or 20 mg/kg daily for 2 days.

Oral

Enterobiasis

Adult: 10 mg/kg repeated once after 2-4 wk. Max dose: 1 g/dose.

Oral

Trichinosis

Adult: 10 mg/kg daily for 5 days.

How should I use Thelmex?

Use Thelmex as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Thelmex.

Thelmex description

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Thelmex is an antinematodal thiophene

Thelmex dosage

Thelmex Dosage

Applies to the following strength(s): 144 mg/mL; 180 mg; 50 mg/mL

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Enterobiasis

11 mg/kg base (maximum 1 g) orally once. Repeat dose in 2 weeks.

Usual Adult Dose for Pinworm Infection (Enterobius vermicularis)

11 mg/kg base (maximum 1 g) orally once. Repeat dose in 2 weeks.

Usual Adult Dose for Hookworm Infection (Necator or Ancylostoma)

11 mg/kg base (maximum 1 g) orally daily for 3 days.

Usual Adult Dose for Ascariasis

11 mg/kg base (maximum 1 g) orally once.

Usual Adult Dose for Trichostrongylosis

11 mg/kg base (maximum 1 g) orally once.

Usual Adult Dose for Moniliformis Infection

11 mg/kg base (maximum 1 g) orally once. Repeat dose twice at 2 weeks intervals.

Usual Pediatric Dose for Enterobiasis

>=2 years: 11 mg/kg base (maximum 1 g) once. Repeat dose in 2 weeks.

Usual Pediatric Dose for Pinworm Infection (Enterobius vermicularis)

>=2 years: 11 mg/kg base (maximum 1 g) once. Repeat dose in 2 weeks.

Usual Pediatric Dose for Hookworm Infection (Necator or Ancylostoma)

>=2 years: 11 mg/kg base (maximum 1 g) orally daily for 3 days.

Usual Pediatric Dose for Ascariasis

>=2 years: 11 mg/kg base (maximum 1 g) orally once.

Usual Pediatric Dose for Trichostrongylosis

>=2 years: 11 mg/kg base (maximum 1 g) orally once.

Usual Pediatric Dose for Moniliformis Infection

>=2 years: 11 mg/kg base (maximum 1 g) orally once. Repeat dose twice at 2 weeks intervals.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Thelmex is contraindicated in patients with hepatic disease.

Dose Adjustments

In the treatment of ascariasis, Thelmex may be used only if it has been determined that the worm load will not worsen obstruction.

Precautions

Thelmex is contraindicated in patients with hepatic disease.

When one individual in a household has pinworms, the entire household should be treated unless otherwise advised. Pinworm infections are easily transmitted to others in the same household.

Thelmex should be used with caution in patients with severe malnutrition or anemia. Supportive therapy is recommended for anemic, dehydrated, or malnourished patients prior to administration of the drug.

Other medications are known to antagonize the anthelmintic effect of Thelmex. Patients should be advised to consult with their physician before initiating any drug therapy while receiving Thelmex.

Dialysis

Data not available

Other Comments

The dose should be taken as a single oral dose. It may be taken alone or with milk or fruit juice.

Thelmex 2.9 g is approximately equivalent to 1 g of Thelmex (base).

More about Thelmex

Consumer resources

Professional resources

Related treatment guides

Thelmex interactions

See also:
What other drugs will affect Thelmex?

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• Dexamethasone

Steady-state trough concentrations of albendazole sulfoxide were about 56% higher when 8 mg dexamethasone was coadministered with each dose of albendazole (15 mg/kg/day) in 8 neurocysticercosis patients.

• Praziquantel

• Cimetidine

Albendazole sulfoxide concentrations in bile and cystic fluid were increased (about 2-fold) in hydatid cyst patients treated with cimetidine (10 mg/kg/day) (n = 7) compared with albendazole (20 mg/kg/day) alone (n = 12). Albendazole sulfoxide plasma concentrations were unchanged 4 hours after dosing.

• Theophylline

The pharmacokinetics of theophylline (aminophylline 5.8 mg/kg infused over 20 minutes) were unchanged following a single oral dose of albendazole (400 mg) in 6 healthy subjects.

Thelmex side effects

See also:
What are the possible side effects of Thelmex?

Applies to Thelmex: oral suspension, oral tablet, oral tablet chewable

In addition to its needed effects, some unwanted effects may be caused by Thelmex (the active ingredient contained in Thelmex). In the event that any of these side effects do occur, they may require medical attention.

Severity: Moderate

If any of the following side effects occur while taking Thelmex, check with your doctor or nurse as soon as possible:

Rare

Minor Side Effects

Some of the side effects that can occur with Thelmex may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common:

Thelmex contraindications

See also:
What is the most important information I should know about Thelmex?

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This medicine is contraindicated in patients with known hypersensitivity to the benzimidazole class of compounds or any components of this medicine.

Active ingredient matches for Thelmex:

Pyrantel in India.

Pyrantel pamoate in India.


Unit description / dosage (Manufacturer)Price, USD
Thelmex 250mg TAB / 3$ 0.14
Thelmex 200mg x 5mL SUSP / 8$ 0.10
Thelmex 250 mg Tablet$ 0.05
Thelmex 10 ml Suspension$ 0.05
THELMEX tab 250 mg x 3's (BPL Pharma)$ 0.14
THELMEX oral susp 200 mg x 5 mL x 10ml (BPL Pharma)$ 0.10

List of Thelmex substitutes (brand and generic names):

Drug Premix; Oral; Pyrantel Tartrate 10.6 g / kg
Paste; Oral; Pyrantel Pamoate 3.58 g
Suspension; Oral; Pyrantel Pamoate 50 mg / ml
Tolworm 10 ml Suspension (Tosc International Pvt Ltd.)$ 0.01
Wormica SD 250mg Suspension (Indica Laboratories Pvt Ltd)$ 0.21
WORMICA-SD 250MG SYRUP 1 bottle / 10 ML syrup each (Indica Laboratories Pvt Ltd)$ 0.21

References

  1. PubChem. "PYRANTEL". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "Pyrantel". http://www.drugbank.ca/drugs/DB11156 (accessed September 17, 2018).
  3. MeSH. "Antinematodal Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Thelmex are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Thelmex. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

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1 consumer reported age

Users%
16-291
100.0%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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