Tropican Uses

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What is Tropican?

Tropican is used to dilate (enlarge) the pupil so that the doctor can see into the back of your eye. It is used before eye examinations, such as cycloplegic refraction and examination of the fundus of the eye. Tropican may also be used before and after eye surgery.

Tropican is available only with your doctor's prescription.

Tropican indications

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Ophthalmic

Production of mydriasis

Adult: Instill 1-2 drops of a 0.5% solution 15-20 minutes before examination.

Ophthalmic

Production of cycloplegia

Adult: Instill 1-2 drops of a 1% solution repeated after 5 minutes. An additional drop may be admin after 20-30 minutes for prolonged effect.

How should I use Tropican?

Use Tropican as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Tropican.

Uses of Tropican in details

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This medication is used to widen (dilate) the pupil of the eye in preparation for certain eye examinations. It belongs to a class of drugs known as anticholinergics. Tropican works by relaxing certain eye muscles.

OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

This medication is also used to treat swelling in different parts of the eye (e.g., iritis, iridocyclitis, keratitis).

How to use Tropican ophthalmic

To apply eye drops, wash your hands first. To avoid contamination, do not touch the dropper tip or let it touch your eye or any other surface.

If you are wearing contact lenses, remove them before using this medication. Ask your doctor when you may replace your contact lenses.

Tilt your head back, look upward, and pull down the lower eyelid to make a pouch. Hold the dropper directly over your eye and place 1 or 2 drops into the pouch, usually 15 to 20 minutes before an eye examination or as directed by your doctor. Look downward and gently close your eyes for 1 to 2 minutes. Place one finger at the corner of your eye (near the nose) and apply gentle pressure for 2 to 3 minutes. This will prevent the medication from draining out and being absorbed by your body. Try not to blink and do not rub your eye. Repeat these steps for your other eye if so directed.

Do not rinse the dropper. Replace the dropper cap after each use.

If you are using another kind of eye medication (e.g., drops or ointments), wait at least 5 to 10 minutes before applying other medications. Use eye drops before eye ointments to allow the drops to enter the eye.

Wash your hands after using this medication. If giving this medication to a child, do not let the medication get into the child's mouth. Also wash the child's hands after giving this medication.

Tropican description

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One of the muscarinic antagonists with pharmacologic action similar to atropine and used mainly as an ophthalmic parasympatholytic or mydriatic. [PubChem]

Tropican dosage

Usual Adult Dose for Refraction

Cycloplegic Refraction:

-Instill 1 or 2 drops of the 1% solution into eye(s); repeat in 5 minutes.

Comment:

-An additional drop may be given if the examination is not done within 20 to 30 minutes.

Use: To produce mydriasis and cycloplegia for diagnostic procedures.

Usual Adult Dose for Pupillary Dilation

Fundoscopy:

-Instill 1 or 2 drops of 0.5% solution into eye(s) 15 or 20 minutes prior to examination.

Comments:

-Heavily pigmented irides may require higher strength or more doses.

Use: To produce mydriasis and cycloplegia for diagnostic procedures.

Usual Pediatric Dose for Refraction

Cycloplegic Refraction:

-Instill 1 or 2 drops of the 1% solution into eye(s); repeat in 5 minutes.

Comment:

-An additional drop may be given if the examination is not done within 20 to 30 minutes.

Use: To produce mydriasis and cycloplegia for diagnostic procedures.

Usual Pediatric Dose for Pupillary Dilation

Fundoscopy:

-Instill 1 or 2 drops of 0.5% solution into eye(s) 15 or 20 minutes prior to examination.

Comments:

-Heavily pigmented irides may require higher strength or more doses.

Use: To produce mydriasis and cycloplegia for diagnostic procedures.

Renal Dose Adjustments

No dosage adjustment is recommended.

Liver Dose Adjustments

No dosage adjustment is recommended.

Dose Adjustments

Use caution in inflamed eyes as hyperemia greatly increases the rate of systemic absorption through the conjunctiva.

Heavily pigmented irides may require higher strength or more doses.

Systemic absorption can be minimized by applying pressure to the lacrimal duct for 1 to 2 minutes after instillation.

Precautions

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

-For topical use only, not for injection

-Contact lenses should be removed before use.

-Wash hands after administration to avoid accidental ingestion.

-Systemic absorption may be minimized by applying pressure to the lacrimal duct for 1 minute after instillation.

Storage requirements:

Store at 8C to 27C (46F to 80F); do not refrigerate; protect from light; keep container tightly closed.

General:

-Patients with heavily pigmented irides may require higher strength or more doses.

-Complete recovery from mydriasis may take up to 24 hours.

Patient advice:

-Patients should be advised to apply pressure to the lacrimal sac for 1 to 3 minutes after instillation, to minimize systemic absorption (especially in children).

-Parents should be warned about oral toxicity with accidental ingestion, and advised to wash their hands and the child's hands after use.

-Patients should be advised to protect eyes from bright light during dilation.

-Patients should be advised not to drive or perform potentially hazardous activities while pupils are dilated.

Tropican interactions

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Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: antihistamines (e.g., diphenhydramine, meclizine), antispasmodics (e.g., dicyclomine), certain anti-arrhythmic drugs (e.g., quinidine), certain drugs for Parkinson's disease (e.g., anticholinergics such as benztropine, trihexyphenidyl), MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine), other eye medications, tricyclic antidepressants (e.g., amitriptyline).

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Tropican side effects

See also:
What are the possible side effects of Tropican?

Applies to Tropican ophthalmic: ophthalmic solution

As well as its needed effects, Tropican ophthalmic may cause unwanted side effects that require medical attention.

Severity: Moderate

If any of the following side effects occur while taking Tropican ophthalmic, check with your doctor or nurse as soon as possible:

Symptoms of too much medicine being absorbed into the body

Minor Side Effects

Some Tropican ophthalmic side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common:

Tropican contraindications

See also:
What is the most important information I should know about Tropican?

PAREMYD® Solution (hydroxyamphetamine hydrobromide/Tropican ophthalmic solution)1%/0.25% should not be used in patients with angle-closure glaucoma or in those with narrow angles in whom dilation of the pupil may precipitate an attack of angle-closure glaucoma. This product is also contraindicated in patients who are hypersensitive to any of its components.

Active ingredient matches for Tropican:

Tropicamide in Taiwan.


Unit description / dosage (Manufacturer)Price, USD
Tropican 0.5 % x 5 mL
Tropican 1 % x 5 mL

List of Tropican substitutes (brand and generic names):

Tropicacyl 0.5% eye drops$ 0.67
Tropicamide 0.4 % x 5 mL
Tropicamide 0.5 % x 5 mL
Tropicamide 1 % x 5 mL
Tropicamide solution/ drops 10 mg/mL (Bausch & Lomb Incorporated (US))
Tropicamide solution/ drops 5 mg/mL (Bausch & Lomb Incorporated (US))
Solution; Ophthalmic; Tropicamide 0.5%
Drops; Ophthalmic; Tropicamide 0.5%
Tropico Eye 5 ml Drop (Bell Pharma Pvt. Ltd.)$ 0.45
TROPICO 1% EYE DROPS 1 packet / 5 ML eye drop each (Bell Pharma Pvt. Ltd.)$ 0.65
Tropico 1% Eye Drop (Bell Pharma Pvt. Ltd.)$ 0.65
TROPICO BELL 1% EYE DROPS 1 packet / 5 ML eye drop each (Bell Pharma Pvt Ltd)$ 0.61
Tropind Eye 5 ml Drop (Biomedica International)$ 0.07
Tropind Plus Eye 5 ml Drop (Biomedica International)$ 0.09
Tropiriv Plus Eye 3 ml Drop (East African (I) Remedies Pvt Ltd)$ 0.33

References

  1. DailyMed. "HYDROXYAMPHETAMINE HYDROBROMIDE; TROPICAMIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "tropicamide". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "tropicamide". http://www.drugbank.ca/drugs/DB00809 (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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