Uni-Ramine Uses

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Uni-Ramine indications

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Infectious-inflammatory diseases caused by microorganisms susceptible to ciprofloxacin, including respiratory diseases, diseases of abdominal and pelvic organs, bones, joints, skin, septicemia; severe infections of ENT organs. Treatment of postoperative infections. Prevention and treatment of infections in patients with reduced immunity.

For Uni-Ramine Citadel Fine Pharmaceuticals local use: acute and subacute conjunctivitis, blepharoconjunctivitis, blepharitis, bacterial corneal ulcers, keratitis, keratoconjunctivitis, chronic dacryocystitis, meybomity. Infectious lesions in the eyes from injury or contact with foreign bodies. Preoperative prophylaxis in ophthalmic surgery.

Uni-Ramine description

A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine. [PubChem]

Uni-Ramine dosage

Individual. For oral administration dose of Uni-Ramine Citadel Fine Pharmaceuticals is 250-750 mg 2 times / day. Treatment duration is from 7-10 days to 4 weeks.

For IV administration a single dose is 200-400 mg, the multiplicity of the introduction is 2 times / day, duration of treatment - 1-2 weeks and more if necessary. May be IV injected as jet but more preferably a drip for 30 minutes.

When Uni-Ramine Citadel Fine Pharmaceuticals applied topically instilled 1-2 drops into the lower conjunctival sac of the affected eye every 1-4 hours. After improving the intervals between instillation can be increased. The maximum oral daily dose for adults is 1.5 g.

Uni-Ramine interactions

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Activity increases when combined with beta-lactam antibiotics, aminoglycosides, vancomycin, clindamycin, metronidazole. Sukralfat, bismuth preparations, antacids containing aluminum ions, magnesium or calcium, cimetidine, ranitidine, vitamin and mineral supplement, iron sulfate, zinc, didanosine (recommended for 2 hours before or 4 hours after these drugs) reduce the suction. Probenecid, azlocillin increase the concentration in the blood. Decreases clearance and increases in plasma caffeine, aminophylline and theophylline (increased likelihood of side effects). Uni-Ramine Citadel Fine Pharmaceuticals enhances the effect of warfarin and other oral anticoagulants (prolongs bleeding time). Increases nephrotoxicity of cyclosporine, increase the risk of CNS excitability and convulsive reactions against the background of NSAIDs. Medicines alkalinizing the urine (citrates, sodium bicarbonate, carbonic anhydrase inhibitors) reduce the solubility (increases the probability of crystalluria). Infusion solutions of ciprofloxacin ready to use can be combined with infusion solutions: 0.9% sodium chloride solution, Ringer's solution, Ringer lactate, 5 and 10% dextrose, 10% solution of fructose, and a solution containing 5% dextrose with 0,225 or 0.45% sodium chloride. Incompatible with solutions having a pH > 7.

Uni-Ramine side effects

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Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Rare

Fever

skin rash or itching

sore throat and fever

unusual tiredness and weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Abdominal or stomach pain or upset

diarrhea

nausea or vomiting

Rare

Dizziness

hair loss

headache

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Uni-Ramine contraindications

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Injection: Uni-Ramine is contraindicated in comatose states, in patients who have received large amounts of central-nervous-system depressants (alcohol, sedative hypnotics, including barbiturates, general anesthetics, narcotics, narcotic analgesics, tranquilizers, etc.), and in patients who have demonstrated an idiosyncrasy or hypersensitivity to promethazine.

Under no circumstances should promethazine be given by intra-arterial injection due to the likelihood of severe arteriospasm and the possibility of resultant gangrene

Uni-Ramine HCl injection should not be given by the subcutaneous route; evidence of chemical irritation has been noted, and necrotic lesions have resulted on rare occasions following subcutaneous injection. The preferred parenteral route of administration is by deep intramuscular injection.

Syrup, Tablets and Suppositories: Phenergan Tablets and Suppositories are contraindicated for use in pediatric patients less than two years of age.

Phenergan Tablets and Suppositories are contraindicated in comatose states, and in individuals known to be hypersensitive or to have had an idiosyncratic reaction to promethazine or to other phenothiazines.

Antihistamines are contraindicated for use in the treatment of lower respiratory tract symptoms including asthma.



Active ingredient matches for Uni-Ramine:

Chlorphenamine in Hong Kong.

Chlorphenamine maleate in Hong Kong.

Chlorpheniramine maleate in Hongkong.


Unit description / dosage (Manufacturer)Price, USD
Uni-Ramine 4 mg x 500's
Uni-Ramine 2 mg/5 mL x 450 mL$ 20.00
Uni-Ramine 2 mg/5 mL x 3.6 L$ 85.00
Uni-Ramine 4 mg/5 mL x 450 mL
Uni-Ramine 4 mg/5 mL x 3.6 L

List of Uni-Ramine substitutes (brand and generic names):

Tuswin Syrup (Patson Laboratories Pvt.Ltd.)$ 0.47
Varcold Tablet (Zota Healthcare Pvt. Ltd.)$ 0.02
Vartus D 100 ml Syrup (Zota Healthcare Pvt. Ltd.)$ 0.02
Velma 60 ml Syrup (Corvin Pharmaceuticals)$ 0.03
Vencof -SF Chlorepheniramine maleate 4mg, Ammon CL 75mg, Phenylpropanolamine 12.5mg, NaCitrate 50mg, Menthol 1mg SYR / 100ml$ 0.43
Vencof-SF Chlorepheniramine maleate 4mg, Ammon CL 75mg, Phenylpropanolamine 12.5mg, NaCitrate 50mg, Menthol 1mg SYR / 100ml$ 0.43
Ventasol -AP Ambroxol HCI 15mg, Guaiphenesin 50mg, Phenylpropanolamine 12.5mg, Chlorepheniramine maleate 2mg SYR / 100ml$ 0.47
Ventasol-AP Ambroxol HCI 15mg, Guaiphenesin 50mg, Phenylpropanolamine 12.5mg, Chlorepheniramine maleate 2mg SYR / 100ml (Intra Labs)$ 0.47
VENTASOL-AP syr 100ml (Intra Labs)$ 0.59
Wicket DS 60 ml Suspension (Nuclear Pharmaceuticals)$ 0.03
Wikoryl ND 60+4 Tablet (Alembic Chemical Works Co Ltd)$ 0.07
WIKORYL ND 4 MG/60 MG TABLET 1 strip / 10 tablets each (Alembic Chemical Works Co Ltd)$ 0.87
Wikoryl TAB Paracetamol 500mg, Caffeine30mg, ChlorepheniramineMaleate 2mg, Phenylephrine HCI10mg TAB / 10 (Alembic)$ 0.19
10's (Alembic)$ 0.25
Wikoryl Tab Paracetamol 500 mg, Caffeine16 mg, Chlorpheniraminemaleate 2 mg, Phenylephrinehydrochloride 5 mg. TAB / 10 (Alembic)$ 0.25
WIKORYL TAB tab 10's (Alembic)$ 0.31
Wikoryl Tab Paracetamol 500 mg, Caffeine16 mg, Chlorpheniraminemaleate 2 mg, Phenylephrinehydrochloride 5 mg. TAB / 10 (Alembic)$ 0.25
Wikoryl Tablet (Alembic Chemical Works Co Ltd)$ 0.03
Wincof D 60 ml Syrup (Winsun Laboratories)$ 0.03
Wincof D 100 ml Syrup (Winsun Laboratories)$ 0.03
Woodrock 100 ml Syrup (Woodrock Healthcare Pvt. Ltd.)$ 0.02
Xecouf 2.5+7.5+7.5 Tablet (Xenium-Cura)$ 0.02
Xeroc D 100 ml Syrup (PRG Pharma Pvt. Ltd.)$ 0.03
Xetuss DX 100 ml Syrup (Biosearch Organics (Ultramark Healthcare Pvt Ltd)$ 0.03
Xetuss DX 60 ml Syrup (Biosearch Organics (Ultramark Healthcare Pvt Ltd)$ 0.03
Xing Cuf 100 ml Syrup (Bindlysh Biotech Ltd)$ 0.04
XL 80 10+2 Tablet (DWD Pharmaceuticals Ltd.)$ 0.04
XL 80 100 ml Expectorant (DWD Pharmaceuticals Ltd.)$ 0.03
XL 80 4MG/10MG TABLET 1 strip / 10 tablets each (DWD Pharmaceuticals Ltd.)$ 0.53
XL 80 4MG/10MG TABLET 1 strip / 15 tablets each (DWD Pharmaceuticals Ltd.)$ 0.53
XL 80 4 mg/10 mg Syrup (DWD Pharmaceuticals Ltd.)$ 0.79
XL 80 4 mg/10 mg Tablet (DWD Pharmaceuticals Ltd.)$ 0.05
Xynex AM 100 ml Syrup (Octane Biotech Pvt. Ltd.)$ 0.02
Zerfy P 4+2+2 Tablet (Romark Health Care)$ 0.01
Zoramine 4 mg/5 mL x 90 mL (Intact)
Zoramine elixir 4 mg/5 mL 90 mL x 1's (Intact)
Zota Cold Tablet (Zota Healthcare Pvt. Ltd.)$ 0.02
Zycof D 100 ml Syrup (HOS & INS)$ 0.03

References

  1. DailyMed. "CHLORPHENIRAMINE POLISTIREX; HYDROCODONE POLISTIREX: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "chlorpheniramine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "chlorpheniramine". http://www.drugbank.ca/drugs/DB01114 (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Uni-Ramine are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Uni-Ramine. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet


Consumer reported price estimates

No survey data has been collected yet


1 consumer reported time for results

To what extent do I have to use Uni-Ramine before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 2 days and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Uni-Ramine. To get the time effectiveness of using Uni-Ramine drug by other patients, please click here.
Users%
2 days1
100.0%


6 consumers reported age

Users%
1-53
50.0%
> 601
16.7%
< 11
16.7%
6-151
16.7%


Consumer reviews


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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