Urecholine Chloride Uses

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What is Urecholine Chloride?

Urecholine Chloride is taken to treat certain disorders of the urinary tract or bladder. It helps to cause urination and emptying of the bladder. Urecholine Chloride may also be used for other conditions as determined by your doctor.

Urecholine Chloride is available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, Urecholine Chloride is used in certain patients with the following medical conditions:

Urecholine Chloride indications

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Urecholine Chloride Chloride Tablets USP are indicated for the treatment of acute postoperative and postpartum nonobstructive (functional) urinary retention and for neurogenic atony of the urinary bladder with retention.

How should I use Urecholine Chloride?

Use Urecholine Chloride as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Urecholine Chloride.

Uses of Urecholine Chloride in details

Urecholine Chloride is used to treat acute urirary retention after surgrey, childbirth and due to various diseases of the urinary bladder. Urecholine Chloride may also be used for treating a disease called congenital megacolon (abnormal dilatation of large intestine which is present from birth) and gastro-esophageal reflux and reflux esophagitis (inflammation of the esophagus due to regurgitation).

Urecholine Chloride description

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Urecholine Chloride is a synthetic ester structurally and pharmacologically related to acetylcholine. A slowly hydrolyzed muscarinic agonist with no nicotinic effects, Urecholine Chloride is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, cardiac rate changes, and bronchial spasms. [PubChem]

Urecholine Chloride dosage

Urecholine Chloride Dosage

Generic name: Urecholine Chloride CHLORIDE 5mg

Dosage form: tablet

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Dosage must be individualized, depending on the type and severity of the condition to be treated.

Preferably give the drug when the stomach is empty. If taken soon after eating, nausea and vomiting may occur.

The usual adult oral dose ranges from 10 to 50 mg three or four times a day. The minimum effective dose is determined by giving 5 to 10 mg initially and repeating the same amount at hourly intervals until satisfactory response occurs, or until a maximum of 50 mg has been given. The effects of the drug sometimes appear within 30 minutes and are usually maximal within 60 to 90 minutes. The drug effects persist for about one hour.

If necessary, the effects of the drug can be abolished promptly by atropine (seeOVERDOSAGE).

More about Urecholine Chloride (Urecholine Chloride)

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Urecholine Chloride interactions

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What other drugs will affect Urecholine Chloride?

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Acetylcholinesterase Inhibitors: May enhance the adverse/toxic effect of Cholinergic Agonists. Monitor therapy

Beta-Blockers: May enhance the adverse/toxic effect of Cholinergic Agonists. Of particular concern are the potential for cardiac conduction abnormalities and bronchoconstriction. Monitor therapy

Cimetropium: Cholinergic Agonists may diminish the anticholinergic effect of Cimetropium. Monitor therapy

Sincalide: Drugs that Affect Gallbladder Function may diminish the therapeutic effect of Sincalide. Management: Consider discontinuing drugs that may affect gallbladder motility prior to the use of sincalide to stimulate gallbladder contraction. Consider therapy modification

Urecholine Chloride side effects

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What are the possible side effects of Urecholine Chloride?

Applies to Urecholine Chloride: elixir, solution, tablet

As well as its needed effects, Urecholine Chloride (the active ingredient contained in Urecholine Chloride) may cause unwanted side effects that require medical attention.

Severity: Moderate

If any of the following side effects occur while taking Urecholine Chloride, check with your doctor or nurse as soon as possible:

Rare - more common with the injection

Minor Side Effects

Some Urecholine Chloride side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Less common or rare: - more common with the injection

Urecholine Chloride contraindications

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What is the most important information I should know about Urecholine Chloride?

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Hypersensitivity to Urecholine Chloride chloride tablets, hyperthyroidism, peptic ulcer, latent or active bronchial asthma, pronounced bradycardia or hypotension, vasomotor instability, coronary artery disease, epilepsy, and parkinsonism.

Urecholine Chloride Chloride chloride should not be employed when the strength or integrity of the gastrointestinal or bladder wall is in question, or in the presence of mechanical obstruction; when increased muscular activity of the gastrointestinal tract or urinary bladder might prove harmful, as following recent urinary bladder surgery, gastrointestinal resection and anastomosis, or when there is possible gastrointestinal obstruction; in bladder neck obstruction, spastic gastrointestinal disturbances, acute inflammatory lesions of the gastrointestinal tract, or peritonitis; or in marked vagotonia.

Active ingredient matches for Urecholine Chloride:

Bethanechol


List of Urecholine Chloride substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Bethanechol / Johnson 25 mg x 1000's
Tablet; Oral; Bethanechol Chloride 10 mg (Roberts)
Tablet; Oral; Bethanechol Chloride 25 mg (Roberts)
Tablet; Oral; Bethanechol Chloride 50 mg (Roberts)
Tablet; Oral; Bethanechol Chloride 10 mg (Glenwood)
Tablet; Oral; Bethanechol Chloride 25 mg (Glenwood)
Tablet; Oral; Bethanechol Chloride 5 mg (Glenwood)
Tablet; Oral; Bethanechol Chloride 10 mg
Tablet; Oral; Bethanechol Chloride 25 mg
Tablet; Oral; Bethanechol Chloride 50 mg
PHL-bethanechol Chloride tablet 10 mg (Pharmel Inc (Canada))
PHL-bethanechol Chloride tablet 25 mg (Pharmel Inc (Canada))
PHL-bethanechol Chloride tablet 50 mg (Pharmel Inc (Canada))
Injectable; Injection; Bethanechol Chloride 5 mg / ml (Barr)
Tablet; Oral; Bethanechol Chloride 10 mg (Barr)
Tablet; Oral; Bethanechol Chloride 25 mg (Barr)
Tablet; Oral; Bethanechol Chloride 5 mg (Barr)
Tablet; Oral; Bethanechol Chloride 50 mg (Barr)
100 tablet in 1 bottle (Barr)
Urecholine tablet 5 mg/1 (Barr)
Urecholine tablet 10 mg/1 (Barr)
Urecholine tablet 25 mg/1 (Barr)
Urecholine tablet 50 mg/1 (Barr)
UROTONE Capsule/ Tablet / 25mg / 5x10 units (Samarth Pharma Pvt. Ltd.)$ 11.45
Urotone 25mg TAB / 10 (Samarth Pharma Pvt. Ltd.)$ 1.17
25 mg x 10's (Samarth Pharma Pvt. Ltd.)$ 1.17
Urotone 25 mg Tablet (Samarth Pharma Pvt. Ltd.)$ 0.12
UROTONE 25 MG TABLET 1 strip / 10 tablets each (Samarth Pharma Pvt. Ltd.)$ 1.41
UROTONE tab 25 mg x 10's (Samarth Pharma Pvt. Ltd.)$ 1.17
Urotone 25mg Tablet (Samarth Pharma Pvt. Ltd.)$ 0.14

References

  1. PubChem. "bethanechol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "bethanechol". http://www.drugbank.ca/drugs/DB01019 (accessed September 17, 2018).
  3. MeSH. "Parasympathomimetics". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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