Dosage of Vacanyl in details
Vacanyl Dosage
Applies to the following strength(s): 2.5 mg; 5 mg; 0.2 mg/inh; 1 mg/mL
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Usual Adult Dose for:
- Asthma - Maintenance
- Premature Labor
- Asthma - Acute
Usual Pediatric Dose for:
- Asthma - Acute
- Asthma - Maintenance
Additional dosage information:
- Renal Dose Adjustments
- Liver Dose Adjustments
- Precautions
- Dialysis
Usual Adult Dose for Asthma - Maintenance
Tablets: 5 mg orally 3 times a day at 6 hour intervals during waking hours. May decrease to 2.5 mg/dose if side effects are pronounced. Do not exceed 15 mg in 24 hours.
Inhalation aerosol: 2 inhalations separated by 60 seconds every 4 to 6 hours. Do not repeat more often than every 4 to 6 hours.
Usual Adult Dose for Premature Labor
Tablets: 2.5 to 7.5 mg orally every 6 hours. Therapy should be continued until 36 to 37 weeks gestation.
Continuous intravenous infusion: 10 to 25 mcg/min. Therapy should be continued until labor has been arrested. Maximum dose 80 mcg/min.
Subcutaneous injection: 0.25 mg every 6 hours. Subcutaneous therapy should be continued until labor has been arrested.
Usual Adult Dose for Asthma - Acute
Inhalation aerosol: 2 inhalations separated by 60 seconds every 4 to 6 hours. Do not repeat more often than every 4 to 6 hours.
Subcutaneous Injection: 0.25 mg into the lateral deltoid area. A second 0.25 mg dose can be administered in 15 to 30 minutes if needed. Do not exceed 0.5 mg in 4 hours.
Continuous intravenous infusion: 0.08 to 6 mcg/kg/min.
Usual Pediatric Dose for Asthma - Acute
Subcutaneous Injection: 0.005 to 0.01 mg/kg/dose to a maximum dose of 0.4 mg every 15 to 20 minutes for 2 doses.
Nebulization: 0.01 to 0.03 mg/kg/dose with a minimum dose of 0.1 mg; maximum dose is 2.5 mg diluted with 1 to 2 mL of normal saline every 4 to 6 hours.
Continuous intravenous infusion: 0.08 to 6 mcg/kg/min.
> 12 years:
Inhalation aerosol: 2 inhalations separated by 60 seconds every 4 to 6 hours. Do not repeat more often than every 4 to 6 hours.
Subcutaneous Injection: 0.25 mg into the lateral deltoid area. A second 0.25 mg dose can be administered in 15-30 minutes if needed. Maximum dose 0.5 mg in 4 hours.
Usual Pediatric Dose for Asthma - Maintenance
< 12 years:
Tablets: 0.05 mg/kg/day divided into three doses. Gradually increase to 0.15 mg/kg/day. Maximum dose is 5 mg per day.
>=12 years:
Inhalation aerosol: 2 inhalations separated by 60 seconds every 4 to 6 hours. Do not repeat more often than every 4 to 6 hours.
>=12 <15 years:
Tablets: 2.5 mg orally every 6 to 8 hours. Do not exceed 7.5 mg in 24 hours
>=15 years:
Tablets: 2.5 mg to 5 mg orally every 6 to 8 hours. Do not exceed 15 mg in 24 hours.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
Vacanyl is not approved by the FDA for use as a tocolytic agent. Although Vacanyl and other beta-agonists have been shown to be effective in arresting episodes of premature labor, there are few studies which evaluate its use for maintenance therapy after successful treatment of an episode of premature labor. A meta-analysis of those few studies did not support its use for maintenance therapy.
Dialysis
Data not available
More about Vacanyl
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- En Espanol
- 6 Reviews - Add your own review/rating
Consumer resources
- Vacanyl
- Vacanyl tablets
- Vacanyl (Advanced Reading)
- Vacanyl Subcutaneous (Advanced Reading)
- Other brands: Vacanyl
Professional resources
- Vacanyl (AHFS Monograph)
- More (3) »
Related treatment guides
- Asthma, acute
- Asthma, Maintenance
- Premature Labor
What other drugs will affect Vacanyl?
You should not take Vacanyl if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Vacanyl, especially:
-
a diuretic or "water pill"; or
-
a beta blocker--atenolol, bisoprolol, carvedilol, labetalol, metoprolol, nadolol, nebivolol, propranolol, sotalol, and others.
This list is not complete. Other drugs may interact with Vacanyl, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Vacanyl interactions
Drug Interactions
The concomitant use of Vacanyl with other sympathomimetic agents is not recommended, since the combined effect on the cardiovascular system may be deleterious to the patient
Monoamine Oxidase Inhibitors or Tricyclic Antidepressants: Vacanyl should be administered with extreme caution to patients being treated with monoamine oxidase inhibitors or tricyclic antidepressants, or within 2 weeks of discontinuation of such agents, since the action of Vacanyl on the vascular system may be potentiated
Beta-Blockers Beta-adrenergic receptor blocking agents not only block the pulmonary effect of beta-agonists, such as Vacanyl, but may produce severe bronchospasm in asthmatic patients. Therefore, patients with asthma should not normally be treated with beta-blockers. However, under certain circumstances, e.g., as prophylaxis after myocardial infarction, there may be no acceptable alternatives to the use of beta-adrenergic blocking agents in patients with asthma. In this setting, cardioselective beta-blockers could be considered, although they should be administered with caution
Diuretics The ECG changes and/or hypokalemia that may result from the administration of nonpotassium-sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. Although the clinical significance of these effects is not known, caution is advised in the coadministration of beta-agonists with nonpotassium-sparing diuretics.
References
- DailyMed. "TERBUTALINE SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- MeSH. "Tocolytic Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
- European Chemicals Agency - ECHA. "terbutaline: The European Chemicals Agency (ECHA) is an agency of the European Union which is the driving force among regulatory authorities in implementing the EU's groundbreaking chemicals legislation for the benefit of human health and the environment as well as for innovation and competitiveness.". https://echa.europa.eu/ (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Vacanyl are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Vacanyl. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported frequency of use
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Information checked by Dr. Sachin Kumar, MD Pharmacology