Zodryl AC 80 Uses

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What is Zodryl AC 80?

Zodryl AC 80 is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Codeine (Zodryl AC 80) is a narcotic cough suppressant. It affects the signals in the brain that trigger cough reflex.

Zodryl AC 80 and Codeine (Zodryl AC 80) is a combination medicine used to treat runny nose, sneezing, itching, watery eyes, and cough caused by allergies, the common cold, or the flu.

Zodryl AC 80 and Codeine (Zodryl AC 80) will not treat a cough that is caused by smoking, asthma, or emphysema.

Zodryl AC 80 and Codeine (Zodryl AC 80) may also be used for purposes not listed in this medication guide.

Zodryl AC 80 indications

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Zodryl AC 80 is indicated for the temporary relief of cough, as may occur with the common cold or inhaled irritants, and for the temporary relief of runny nose, sneezing, itching of the nose or throat, and itchy watery eyes due to hay fever, other upper respiratory allergies, or allergic rhinitis.

How should I use Zodryl AC 80?

Use Zodryl AC 80 suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Zodryl AC 80 suspension.

Uses of Zodryl AC 80 in details

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This combination product is used to treat symptoms caused by the common cold, flu, allergies, hay fever, or other breathing illnesses (e.g., sinusitis, bronchitis). This product contains a narcotic cough suppressant (antitussive) that affects a certain part of the brain, reducing the urge to cough. Antihistamines relieve watery eyes, itchy eyes/nose/throat, runny nose, and sneezing.

Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Therefore, this product is not recommended to treat cold symptoms in children younger than 6 years. Some products (including some long-acting tablets/capsules) are not recommended for use in children younger than 12 years. Ask your doctor or pharmacist for more details about using your product safely.

These products do not cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, carefully follow all dosage directions. Giving more than the recommended dose or using this medication along with other cough-and-cold products has resulted in serious (even fatal) side effects, including slowed/stopped breathing. Talk to the doctor or pharmacist before giving other cough-and-cold medication that might contain the same or similar ingredients. Ask about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray). Do not use this product to make a child sleepy.

How to use Zodryl AC 80

Read the Patient Information Leaflet if available from your pharmacist before you start taking this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food with a full glass of water (8 ounces or 240 milliliters) or as directed by your doctor. This medication may be taken with food or milk if stomach upset occurs. Do not take the sustained-release products more often than every 12 hours.

If you are using the liquid form, use a medication measuring device or spoon to carefully measure the prescribed dose. Do not use a household spoon because you may not get the correct dose. If your liquid form is a suspension, shake the bottle well before each dose.

If you are using the extended-release capsules, swallow them whole. Do not crush or chew extended-release capsules or tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.

If you are using a sustained-release liquid that contains hydrocodone polistirex, do not mix the liquid with other liquids or medications. Doing so can destroy the long action of the drug and may increase side effects.

This medication may cause withdrawal reactions, especially if it has been used regularly for a long time (more than a few weeks) or in high doses. In such cases, withdrawal symptoms (such as anxiety, restlessness, sweating, shaking chills, nausea, vomiting, and diarrhea) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details, and report any withdrawal reactions right away.

Though it is very unlikely to occur, this medication can also result in abnormal drug-seeking behavior (addiction/habit forming). Do not increase your dose, take it more frequently, or use it for a longer time than prescribed. Properly stop the medication when so directed. This will lessen the chances of becoming addicted.

When used for an extended time, this medication may not work as well and may require different dosing. Talk with your doctor if this medication stops working well.

Inform your doctor if your condition persists for more than 1 week, if it worsens, or if it occurs with fever, rash, or persistent headache. These may be symptoms of a serious medical problem and should be checked by a doctor.

Zodryl AC 80 dosage

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Zodryl AC 80 Dosage

Generic name: Codeine (Zodryl AC 80) PHOSPHATE 10mg in 5mL, Zodryl AC 80 MALEATE 2mg in 5mL

Dosage form: oral liquid

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Adults and children 12 years of age and over: 1 to 2 teaspoonfuls (5-10 mL) every 4 to 6 hours. Not to exceed 8 teaspoonfuls in a 24 hour period. Children 6 to under 12 years of age: 1/2 to 1 teaspoonful (2.5 - 5 mL) every 4 to 6hours. Not to exceed 4 teaspoonfuls in a 24 hour period.

*In mild cases or in particularly sensitive patients, less frequent or reduced doses may be appropriate and adequate.

More about Zodryl AC 80 (Zodryl AC 80 / Codeine (Zodryl AC 80))

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Zodryl AC 80 interactions

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What other drugs will affect Zodryl AC 80?

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Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: anticholinergic drugs (e.g., benztropine, belladonna alkaloids), antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray), cimetidine, MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine), narcotic antagonists (e.g., naltrexone, naloxone), scopolamine, tricyclic antidepressants (e.g., amitriptyline, desipramine).

Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., Codeine (Zodryl AC 80)), psychiatric medicines (e.g., chlorpromazine, risperidone, trazodone). Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products.

This medication may interfere with certain laboratory tests (including amylase/lipase levels), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Zodryl AC 80 side effects

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What are the possible side effects of Zodryl AC 80?

Adverse reactions listed below have been reported in the literature for Codeine (Zodryl AC 80) and Zodryl AC 80 and may be expected to occur with Zodryl AC 80. Also included are events which occurred during clinical pharmacokinetic studies (in a total of 147 healthy adult volunteers with either single or multiple dose exposure) with Zodryl AC 80 and judged by the investigator to be related to study treatment. There are insufficient data to support a statement regarding distribution of adverse events by gender, race and age.

Body as a Whole

Asthenia, feeling of relaxation, redness or flushing of the face, unusual tiredness or weakness.

Allergic

Allergic laryngospasm, atelectasis, bronchospastic allergic reaction, hives, itching, swelling of face.

Cardiovascular

Fast, slow, or pounding heartbeat, hypertension, hypotension, orthostatic hypotension, palpitation, shock-like state, syncope.

Dermatologic System

Dermatitis, excessive perspiration, urticaria, erythema, pruritus, rash.

Endocrine

Changes in glucose utilization, decreased lactation, early menses, glycosuria, gynecomastia, hypoglycemia, increased appetite, increased libido, pheochromocytoma stimulation.

Gastrointestinal

Abdominal distension, abdominal pain, acute pancreatitis, constipation, diarrhea, dry mouth, dyspepsia, epigastric distress, loss of appetite, nausea, vomiting; also observed with opioids: decreased gastric motility with increased likelihood of esophageal reflux.

Genitourinary

Dysuria, irritative bladder symptoms, urinary frequency, urinary hesitancy, urinary retention, ureteral spasm.

Nervous System

Blurred, double, or other visual disturbances; confusion; dizziness; depression; drowsiness and sedation; headache; euphoria; facial dyskinesia; false sense of well-being; feeling faint, lightheadedness, general feeling of discomfort or illness; may cause excitability, especially in children; nervousness, agitation and restlessness; minimal sedation; somnolence; also observed with antihistamine agents: insomnia, dyskinesia, irritability, tremor.

Respiratory System

Dryness of pharynx and respiratory passages, laryngismus, nasal stuffiness, wheezing or troubled breathing, respiratory depression.

Special Senses

Ears: labyrinthitis, tinnitus, vertigo; eyes: blurred vision, diplopia, hypermetropia, lacrimation increased, mydriasis, photophobia.

Other

Drug fever.

Zodryl AC 80 contraindications

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What is the most important information I should know about Zodryl AC 80?

Patients with hypersensitivity or idiosyncrasy to any of its ingredients. Do not use in newborn infants, premature infants, in nursing mothers, in patients with severe hypertension, severe coronary artery disease, ischemic heart disease, or in those receiving monoamine oxidase (MAO) inhibitors. Zodryl AC 80 Liquid should not be used during pregnancy or in nursing mothers.

Antihistamines are contraindicated in patients with narrow-angle glaucoma, urinary retention, peptic ulcer, and during an asthma attack. Antihistamines should not be used to treat lower respiratory tract conditions including asthma.

Active ingredient matches for Zodryl AC 80:

Chlorpheniramine/Codeine


List of Zodryl AC 80 substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
RECODEX syr 60ml (Schon (Reco))$ 0.25
RESPINEX CD 4MG/10MG SYRUP 1 bottle / 60 ML syrup each (Alembic Pharmaceuticals Ltd)$ 0.31
RESPINEX CD 4MG/10MG SYRUP 1 bottle / 100 ML syrup each (Alembic Pharmaceuticals Ltd)$ 0.42
Respinex CD 4 mg/10 mg Syrup (Alembic Pharmaceuticals Ltd)$ 0.31
REXCOD SYRUP 1 bottle / 100 ML syrup each (Lincoln Pharmaceuticals Ltd)$ 0.75
REXCOF DX SYRUP 1 bottle / 100 ML syrup each (Cipla Ltd)$ 0.84
REXTAS 4MG/10MG SYRUP 1 bottle / 100 ML syrup each (Intas)$ 0.95
REXTAS syr 100ml (Intas)$ 0.86
REXTAS syr 50ml (Intas)$ 0.47
Rextas 4 mg/10 mg Syrup (Intas)$ 0.95
SILENSER 4MG/10MG SYRUP 1 bottle / 50 ML syrup each (Parenteral Drugs)$ 0.40
SILENSER 4MG/10MG SYRUP 1 bottle / 100 ML syrup each (Parenteral Drugs)$ 0.87
SILENSER syr 100ml (Parenteral Drugs)$ 0.84
SOTHREX C SYRUP 1 bottle / 100 ML syrup each (Psychotropics India Ltd)$ 0.38
Supkof 100 ml Syrup (Obsurge Biotech Limited)$ 0.04
SUPKOF 4MG/10MG SYRUP 1 bottle / 100 ML syrup each (Obsurge Biotech Limited)$ 0.78
Supkof 4 mg/10 mg Syrup (Obsurge Biotech Limited)$ 0.60
Supkof T Syrup (Obsurge Biotech Limited)$ 1.19
THIOKOF CD 4MG/10MG SYRUP 1 bottle / 100 ML syrup each (Synthiko Formulations & Pharma Pvt Ltd)$ 0.78
Thiokof CD 4 mg/10 mg Syrup (Synthiko Formulations & Pharma Pvt Ltd)$ 0.78
TRUSTYL CD 4MG/10MG SYRUP 1 bottle / 100 ML syrup each (Abbott India Ltd)$ 0.89
XENOCOF D 4MG/10MG SYRUP 1 bottle / 100 ML syrup each (Orchid Chemicals & Pharmaceuticals Ltd)$ 0.72
Xenocof D 4 mg/10 mg Syrup (Orchid Chemicals & Pharmaceuticals Ltd)$ 0.72
XEPIN COUGH 4MG/10MG SYRUP 1 bottle / 100 ML syrup each (Sysmed Laboratories Pvt Ltd)$ 0.74
Xepin Cough 4 mg/10 mg Syrup (Sysmed Laboratories Pvt Ltd)$ 0.74
XPECT C 4 MG/10 MG SYRUP 1 bottle / 100 ML syrup each (Alkem Laboratories Ltd)$ 0.93

References

  1. DailyMed. "CHLORPHENIRAMINE POLISTIREX; HYDROCODONE POLISTIREX: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DailyMed. "CODEINE SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  3. PubChem. "codeine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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