What is Folat-5?
Vitamins are compounds that you must have for growth and health. They are needed in small amounts only and are usually available in the foods that you eat. Folat-5 (vitamin B 9) is necessary for strong blood.
Lack of Folat-5 may lead to anemia (weak blood). Your health care professional may treat this by prescribing Folat-5 for you.
Some conditions may increase your need for Folat-5. These include:
- Alcoholism
- Anemia, hemolytic
- Diarrhea (continuing)
- Fever (prolonged)
- Hemodialysis
- Illness (prolonged)
- Intestinal diseases
- Liver disease
- Stress (continuing)
- Surgical removal of stomach
In addition, infants smaller than normal, breast-fed infants, or those receiving unfortified formulas (such as evaporated milk or goat's milk) may need additional Folat-5.
Increased need for Folat-5 should be determined by your health care professional.
Some studies have found that Folat-5 taken by women before they become pregnant and during early pregnancy may reduce the chances of certain birth defects (neural tube defects).
Claims that Folat-5 and other B vitamins are effective for preventing mental problems have not been proven. Many of these treatments involve large and expensive amounts of vitamins.
Injectable Folat-5 is given by or under the direction of your health care professional. Another form of Folat-5 is available without a prescription.
Folat-5 indications
Folat-5 is used in the treatment and prevention of the folate deficiency state. It does not correct folate deficiency due to dihydrofolate reductase inhibitors. Folat-5 is also used in women of child-bearing potential and pregnant women to protect against neural tube defects in their offspring. It is also used for the treatment of folate-deficient megaloblastic anaemia, chronic haemolytic states such as thalassaemia major or sickle-cell anaemia.
How should I use Folat-5?
Use Folat-5 as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Folat-5 may be administered as an injection by your health care professional.
- If you are using Folat-5 at home, carefully follow the injection procedures taught to you by your health care provider. If the medicine contains particles, is discolored, or if the vial is cracked or damaged in any way, do not use it.
- Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor, nurse, or pharmacist to explain local regulations for selecting an appropriate container and properly disposing of the container when full.
- If you miss a dose of Folat-5, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Folat-5.
Uses of Folat-5 in details
Folat-5 is the man-made form of folate. Folate is a B-vitamin naturally found in some foods. It is needed to form healthy cells, especially red blood cells.
Folat-5 supplements may come in different forms (such as L-methylfolate, levomefolate, methyltetrahydrofolate). They are used to treat or prevent low folate levels. Low folate levels can lead to certain types of anemia. Conditions that can cause low folate levels include poor diet, pregnancy, alcoholism, liver disease, certain stomach/intestinal problems, kidney dialysis, among others. Women of childbearing age should receive adequate amounts of Folat-5 either through their diet or supplements to prevent infant spinal cord birth defects.
How to use Folat-5
Take this product by mouth with or without food as directed by your doctor, usually once daily. If you are taking the over-the-counter product, follow all directions on the product package. If you have any questions, ask your doctor or pharmacist.
Dosage is based on your medical condition and response to treatment. Do not increase your dose or take this product more often than directed.
Take this product regularly to get the most benefit from it. To help you remember, take it at the same time each day. Follow the diet plan recommended by your doctor or dietician. See also Notes section.
If your condition persists or worsens, or if you think you may have a serious medical problem, get medical help right away.
Folat-5 description
A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (poaceae). Folat-5 is used in the treatment and prevention of folate deficiencies and megaloblastic anemia. [PubChem]
Folat-5 dosage
Folat-5 Dosage
Applies to the following strength(s): 1 mg; 0.4 mg; 5 mg/mL; 0.8 mg
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Usual Adult Dose for:
- Megaloblastic Anemia
- Folat-5 Deficiency
Usual Pediatric Dose for:
- Folat-5 Deficiency
- Vitamin/Mineral Supplementation
Additional dosage information:
- Renal Dose Adjustments
- Liver Dose Adjustments
- Dose Adjustments
- Dialysis
- Other Comments
Usual Adult Dose for Megaloblastic Anemia
1 mg orally, intramuscularly, subcutaneously or IV once a day. May continue until clinical symptoms of folate deficiency and the hematological profile have normalized.
Usual Adult Dose for Folat-5 Deficiency
400 to 800 mcg orally, intramuscularly, subcutaneously or IV once a day.
Women of childbearing age, pregnant, and lactating women: 800 mcg orally, intramuscularly, subcutaneously or IV once a day.
Usual Pediatric Dose for Folat-5 Deficiency
Infant:
0.1 mg orally, intramuscularly, subcutaneously or IV once a day.
Child:
Less than 4 years: up to 0.3 mg orally, intramuscularly, subcutaneously or IV once a day.
4 years or older: 0.4 mg orally, intramuscularly, subcutaneously or IV once a day.
Usual Pediatric Dose for Vitamin/Mineral Supplementation
Recommended daily allowance (RDA):
Premature neonates: 50 mcg/day (15 mcg/kg/day).
Full-term neonates and infants 1 to 6 months: 25 to 35 mcg/day.
Children:
1 to 3 years: 150 mcg/day.
4 to 8 years: 200 mcg/day.
9 to 13 years: 300 mcg/day.
14 years and older: 400 mcg/day.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Dose Adjustments
Rarely, a dosage of 2 mg/day may be required, particularly in patients with malabsorption, alcoholism, chronic hemolysis, chronic exfoliative skin disease or who are on concomitant anticonvulsant therapy.
Dialysis
Folat-5 is removed by both hemodialysis and peritoneal dialysis. The amount removed varies with type equipment used.
Because folate may accumulate in patients with end-stage renal disease, side effects may be more likely in this patient who is undergoing dialysis. Once this patient's body stores of folate are replete, three times a week dosing may be just as beneficial as once daily dosing but should portend a lower risk of side effects.
Other Comments
The recommended daily allowance of Folat-5 for adult males and females ranges from 150 to 200 and 150 to 180 mcg/day, respectively.
There is a potential danger in administering Folat-5 to patients with undiagnosed anemia, since Folat-5 may obscure the diagnosis of pernicious anemia by alleviating the hematologic manifestations of the disease while allowing the neurologic complications to progress.
Severe megaloblastic anemia may require therapy for 4 to 5 weeks. Once stabilized, if dietary intake is inadequate, maintenance therapy can be started.
More about Folat-5
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Espanol
- 0 Reviews - Add your own review/rating
Consumer resources
- Folat-5
- Folat-5 capsules
- Folat-5
Oral, Injection (Advanced Reading)
- Other brands: Folacin-800, Folat-5
Professional resources
- Folat-5 (AHFS Monograph)
- More (3) »
Related treatment guides
- Folat-5 Deficiency
- Vitamin/Mineral Supplementation and Deficiency
- Anemia, Megaloblastic
Folat-5 interactions
See also:
What other drugs will affect Folat-5?
Medications that interfere with your bodys ability to use folate may also increase the need for this vitamin. Medications can interfere with folate utilization, including: anticonvulsant medications (such as phenytoin, and primidone) metformin (sometimes prescribed to control blood sugar in type 2 diabetes) sulfasalazine (used to control inflammation associated with Crohns disease and ulcerative colitis) triamterene (a diuretic) Methotrexate There has been concern about the interaction between vitamin B12 and Folat-5. Folat-5 supplements can correct the anemia associated with vitamin B12 deficiency. Unfortunately, Folat-5 will not correct changes in the nervous system that result from vitamin B12 deficiency. Permanent nerve damage could theoretically occur if vitamin B12 deficiency is not treated. Therefore, intake of supplemental Folat-5 should not exceed 1000 micrograms (g, sometimes mcg) per day to prevent Folat-5 from masking symptoms of vitamin B12 deficiency. It is important for older adults to be aware of the relationship between Folat-5 and vitamin B12 because they are at greater risk of having a vitamin B12 deficiency. If you are 50 years of age or older, ask your physician to check your B12 status before you take a supplement that contains folic acid.
Folat-5 side effects
See also:
What are the possible side effects of Folat-5?
Allergic sensitization has been reported following both oral and parenteral administration of Folat-5.
Folat-5 is relatively nontoxic in man. Rare instances of allergic responses to Folat-5 preparations have been reported and have included erythema, skin rash, itching, general malaise, and respiratory difficulty due to bronchospasm. One patient experienced symptoms suggesting anaphylaxis following injection of the drug. Gastrointestinal side effects, including anorexia, nausea, abdominal distention, flatulence, and a bitter or bad taste, have been reported in patients receiving 15 mg Folat-5 daily for 1 month. Other side effects reported in patients receiving 15 mg daily include altered sleep patterns, difficulty in concentrating, irritability, overactivity, excitement, mental depression, confusion, and impaired judgment. Decreased vitamin B12 serum levels may occur in patients receiving prolonged Folat-5 therapy.
In an uncontrolled study, orally administered Folat-5 was reported to increase the incidence of seizures in some epileptic patients receiving phenobarbital, primidone, or diphenylhydantoin. Another investigator reported decreased diphenylhydantoin serum levels in folate-deficient patients receiving diphenylhydantoin who were treated with 5 mg or 15 mg of Folat-5 daily.
CALL YOUR DOCTOR FOR MEDICAL ADVICE ABOUT SIDE EFFECTS. YOU MAY REPORT SIDE EFFECTS TO THE FDA AT 1-800-FDA-1088 OR LEADING PHARMA, LLC AT 844-740-7500.
Folat-5 contraindications
See also:
What is the most important information I should know about Folat-5?
Because it may mask the hematologic abnormalities while neurological damage progresses, Folat-5 should not be used in the therapy of patients with vitamin B12 deficiency of any cause, unless there is associated folate deficiency. The Folat-5 content of one tablet a day however, is unlikely to mask pernicious anemia should this condition be present. Also, pregnancy during pernicious anemia is very rare.
Active ingredient matches for Folat-5:
Folic acid in India.
Unit description / dosage (Manufacturer) | Price, USD |
5 mg x 10's | $ 0.11 |
Folat-5 5mg TAB / 10 | $ 0.11 |
FOLAT-5 tab 5 mg x 10's (ATOZ) | $ 0.11 |
Folat-5 5mg TAB / 10 | $ 0.11 |
List of Folat-5 substitutes (brand and generic names): | |
Folasic (Australia) | |
Folate (India) | |
FOLATE film-coated tab 5 mg x 10's (Katg) | $ 0.19 |
Folatine (United Kingdom) | |
Folavicap (Indonesia) | |
Folavit (Belgium, Indonesia, Luxembourg) | |
Folavit 400 mcg x 10 x 10's (Sanbe) | $ 7.56 |
Folavit 1000 mcg x 25 x 4's (Sanbe) | $ 16.74 |
Folavit 4 (Luxembourg) | |
Folaxin (Indonesia, Spain) | |
Folaxin 400 mcg x 10 x 10's (Berlico mulia) | $ 4.32 |
Folbal | |
Folbiol (Turkey) | |
FOLBIT (India) | |
5 mg x 10's (Archicare) | $ 0.15 |
Folbit 5mg TAB / 10 (Archicare) | $ 0.15 |
Folbit 5 mg Tablet (Archicare) | $ 0.02 |
FOLBIT tab 5 mg x 10's (Archicare) | $ 0.15 |
Folbit 5mg TAB / 10 (Archicare) | $ 0.15 |
Folcid (Philippines) | |
Folcidin | |
Folcur (Germany) | |
Tablet; Oral; Folic Acid (1a) | |
Folcysteine | |
Foldine | |
Foldivit (India) | |
Foldivit 5mg TAB / 10 (Genstar (Cadila Pharmaceuticals Ltd.)) | $ 0.10 |
5 mg x 10's (Genstar (Cadila Pharmaceuticals Ltd.)) | $ 0.10 |
Foldivit 5 mg Tablet (Genstar (Cadila Pharmaceuticals Ltd.)) | $ 0.01 |
FOLDIVIT tab 5 mg x 10's (Genstar (Cadila Pharmaceuticals Ltd.)) | $ 0.10 |
Foleq (Philippines) | |
Foleq 5 mg x 30's (Virgo) | $ 5.42 |
Foleq 5 mg x 100's (Virgo) | $ 18.06 |
Foleq tab 5 mg 100's (Virgo) | |
Foleq tab 5 mg 30's (Virgo) | |
FOLERA | |
5 mg x 30's (Sigma Division (Svizera Healthcare) (Maneesh Pharmaceuticals Pvt Ltd)) | $ 0.72 |
Folera 5mg TAB / 30 (Sigma Division (Svizera Healthcare) (Maneesh Pharmaceuticals Pvt Ltd)) | $ 0.72 |
Folera 5 mg Tablet (Sigma Division (Svizera Healthcare) (Maneesh Pharmaceuticals Pvt Ltd)) | $ 0.02 |
FOLERA tab 5 mg x 30's (Sigma Division (Svizera Healthcare) (Maneesh Pharmaceuticals Pvt Ltd)) | $ 0.72 |
Folera 5mg TAB / 30 (Sigma Division (Svizera Healthcare) (Maneesh Pharmaceuticals Pvt Ltd)) | $ 0.72 |
Folessa (Bosnia & Herzegowina) | |
Folet (India) | |
Folet 5mg TAB / 30 (Centaur Pharmaceuticals Pvt.Ltd.) | $ 0.50 |
5 mg x 30's (Centaur Pharmaceuticals Pvt.Ltd.) | $ 0.50 |
Folet 5 mg Tablet (Centaur Pharmaceuticals Pvt.Ltd.) | $ 0.02 |
FOLET tab 5 mg x 30's (Centaur Pharmaceuticals Pvt.Ltd.) | $ 0.50 |
Folettes | |
Folfa (Georgia) | |
FOLFINE (India) | |
FOLFINE tab 5 mg x 10's (Finecure) | |
Folgamma Mono (Germany) | |
Tablet; Oral; Folic Acid 5 mg (Worwag) | |
See 1352 substitutes for Folat-5 |
References
- DailyMed. "ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PHYTONADIONE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN 5'-PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "folic acid". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "folic acid". http://www.drugbank.ca/drugs/DB00158 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Folat-5 are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Folat-5. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yet1 consumer reported age
Users | % | ||
---|---|---|---|
30-45 | 1 | 100.0% |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology