What is Hhfudic?
Hhfudic is a substance that is used to treat bacterial infections. It will not work for colds, flu, or other virus infections.
Hhfudic is available only with your doctor's prescription.
Hhfudic indications
Hhfudic is active in vitro against Staphylococcus aureus, most coagulase-negative staphylococci, Corynebacterium species, most clostridium species. Hhfudic has no useful activity against enterococci or most Gram-negative bacteria (except Neisseria, Moraxella, Legionella pneumophila and Bacteroides fragilis). Hhfudic is active in vitro and clinically against Mycobacterium leprae but has only marginal activity against Mycobacterium tuberculosis.
One important use of Hhfudic clinically is its activity against methicillin-resistant Staphylococcus aureus. Many strains of MRSA remain sensitive to Hhfudic, but because there is a low genetic barrier to drug resistance (a single point mutation is all that is required), Hhfudic must never be used on its own to treat serious MRSA infection and should be combined with another antimicrobial such as rifampicin.
Hhfudic is often found in topical skin and eye preparations (e.g., Fucibet), a use which has been contested.
Uses of Hhfudic in details
Hhfudic is used for treating various bacterial skin infections and some infections of bone, heart, lungs and eyes.
Hhfudic description
Hhfudic is a bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Hhfudic A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
Hhfudic dosage
Cream/Ointment: Apply to the affected area 2-3 times a day, generally for a period of 7 days.
Hhfudic ointment can be used with or without a covering dressing.
Hhfudic interactions
Hhfudic use in patients who are receiving high doses of theophylline may be associated with an increase in serum theophylline levels and potential theophylline toxicity. In case of theophylline toxicity and/or elevated serum theophylline levels, the dose of theophylline should be reduced while the patient is receiving concomitant erythromycin therapy.
Concomitant administration of erythromycin and digoxin has been reported to result in elevated digoxin serum levels. There have been reports of increased anticoagulant effects when erythromycin and oral anticoagulants were used concomitantly. Increased anticoagulation effects due to interactions of erythromycin with various oral anticoagulents may be more pronounced in the elderly.
Concurrent use of erythromycin and ergotamine or dihydroergotamine has been associated in some patients with acute ergot toxicity characterized by severe peripheral vasospasm and dysesthesia.
Hhfudic has been reported to decrease the clearance of triazolam and midazolam and thus may increase the pharmacologic effect of these benzodiazepines.
The use of erythromycin in patients concurrently taking drugs metabolized by the cytochrome P450 system may be associated with elevations in serum levels of these other drugs. There have been reports of interactions of erythromycin with carbamazepine, cyclosporine, tacrolimus, hexobarbital, phenytoin, alfentanil, cisapride, disopyramide, lovastatin, bromocriptine, valproate, terfenadine, and astemizole. Serum concentrations of drugs metabolized by the cytochrome P450 system should be monitored closely in patients concurrently receiving erythromycin.
Hhfudic has been reported to significantly alter the metabolism of nonsedating antihistamines terfenadine and astemizole when taken concomitantly. Rare cases of serious cardiovascular adverse events, including electrocardiographic QT/QTc interval prolongation, cardiac arrest, torsades de pointes, and other ventricular arrhythmias have been observed. In addition, deaths have been reported rarely with concomitant administration of terfenadine and erythromycin.
There have been postmarketing reports of drug interactions when erythromycin is coadministered with cisapride, resulting in QT prolongation, cardiac arrythmias, ventricular tachycardia, ventricular fibrulation, and torsades de pointes, most like due to inhibition of hepatic metabolism of cisapride by erythromycin. Fatalities have been reported.
Patients receiving concomitant lovastatin and erythromycin should be carefully monitored; cases of rhabdomyolysis have been reported in seriously ill patients.
Hhfudic side effects
See also:
What are the possible side effects of Hhfudic?
Occasionally hypersensitivity reactions eg, skin rashes, weak pain and irritation may occur. If these symptoms occur, discontinue Hhfudic.
Hhfudic contraindications
Hhfudic is contraindicated in patients with known hypersensitivity to this antibiotic. Hhfudic is contraindicated in patients taking terfenadine, astemizole, or cisapride.
Topical Ery 2% Pads are contraindicated in those individuals who have shown hypersensitivity to any of its components.
Active ingredient matches for Hhfudic:
Fusidic Acid in India.
Fusidic Acid Topical/Mometasone Topical
Mometasone furoate in India.
| Unit description / dosage (Manufacturer) | Price, USD |
| Hhfudic Skin 10 gm Cream | $ 1.93 |
| HHFUDIC CREAM 1 tube / 10 GM cream each (Hegde and Hegde Pharmaceutical LLP) | $ 2.65 |
| HHFUDIC cream 10g (H & H) | $ 2.11 |
| Hhfudic Cream (Hegde and Hegde Pharmaceutical LLP) | $ 2.78 |
List of Hhfudic substitutes (brand and generic names): | |
| Gzlcon F | |
| Gzlcon F Skin 10 gm Cream (Gedzrlvin Pharmaceuticals) | $ 1.20 |
| HHSONE (India) | |
| 10g (H&H Pharmaceuticals Pvt Ltd) | $ 0.90 |
| Hhsone Skin 10 gm Cream (H&H Pharmaceuticals Pvt Ltd) | $ 1.08 |
| Hhsone Skin 10 ml Lotion (H&H Pharmaceuticals Pvt Ltd) | $ 1.33 |
| Hhsone 10g CRM / 1 (H&H Pharmaceuticals Pvt Ltd) | $ 0.90 |
| Hhsone 0.1% w/w LOTION / 10ml (H&H Pharmaceuticals Pvt Ltd) | $ 1.25 |
| HHSONE cream 0.1 % x 10g (H&H Pharmaceuticals Pvt Ltd) | $ 0.90 |
| HHSONE lotion 0.1 % w/w x 10ml (H&H Pharmaceuticals Pvt Ltd) | $ 1.25 |
| Hhsone 10g CRM / 1 (H&H Pharmaceuticals Pvt Ltd) | $ 0.90 |
| Hhsone 0.1% w/w LOTION / 10ml (H&H Pharmaceuticals Pvt Ltd) | $ 1.25 |
| HoeFoban (Vietnam) | |
| HoeFoban 2 % x 1 tube 5 g | |
| HoeFoban 2 % x 1 tube 15 g | |
| HoeFoban 2 % x 1 tube 10 g | |
| Hopaq (Philippines) | |
| Hopaq 2 % x 5 g (Hoe) | $ 5.13 |
| Hopaq 2 % x 15 g (Hoe) | $ 9.53 |
| Hylosept (Poland) | |
| Infloc (Portugal) | |
| Infloc 2% (Portugal) | |
| Infusid (Colombia) | |
| Iretien (Paraguay) | |
| Isathal (Norway, Switzerland) | |
| Isathal 1% (Finland) | |
| Isathal 10 mg/g voor honden en katten (Netherlands) | |
| Isathal 10 mg/ml für Hunde For dogs (Austria) | |
| Isathalmic 1% (Sweden) | |
| Kangfujing (Taiwan) | |
| Kangfujing 2 % x 1 g | |
| Kangfujing 2 % x 5 g | |
| Kangfujing 2 % x 8 g | |
| Kangfujing 2 % x 10 g | |
| Kangfujing 2 % x 15 g | |
| Klinidox (Colombia) | |
| Lafusidex (Vietnam) | |
| Lafusidex 2 % x 1 tube 5 g | |
| Lucirex (Pakistan) | |
| M-FACT (India) | |
| 0.05 % x 10g (Medico HC) | $ 0.83 |
| M-Fact 0.05% OINT / 10g (Medico HC) | $ 0.83 |
| M-FACT oint 0.05 % x 10g (Medico HC) | $ 0.83 |
| M-Fact 0.05% OINT / 10g (Medico HC) | $ 0.83 |
| MECLOMA-F (India) | |
| 10g (Esma) | $ 1.33 |
| Mecloma-F Mometasone furoate 0.1 % w/w, Fusidic acid 2 % w/w. CRM / 10g (Esma) | $ 1.33 |
| MECLOMA-F cream 10g (Esma) | $ 1.33 |
| Mecloma-F Mometasone furoate 0.1 % w/w, fusidic acid 2 % w/w. CRM / 10g (Esma) | $ 1.33 |
| MedSkin Fusidic (Vietnam) | |
| MedSkin Fusidic 20 mg x 1 tube 5 g | |
See 849 substitutes for Hhfudic | |
References
- DailyMed. "FORMOTEROL FUMARATE; MOMETASONE FUROATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "mometasone furoate". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- PubChem. "Mometasone". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Hhfudic are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Hhfudic. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yet1 consumer reported price estimates
Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?The below mentioned numbers have been reported by ndrugs.com website users about whether the Hhfudic drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
| Users | % | ||
|---|---|---|---|
| Expensive | 1 | 100.0% | |
Consumer reported time for results
No survey data has been collected yetConsumer reported age
No survey data has been collected yetConsumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
