Mukinol indications
For use Max Pidek Pharmaceuticals as monotherapy and in combination with clavulanic acid: an infectious-inflammatory diseases caused by susceptible microorganisms, including bronchitis, pneumonia, tonsillitis, pyelonephritis, urethritis, infections of the gastrointestinal tract, gynecological infections, infections of the skin and soft tissue, listeria, leptospirosis, gonorrhea.
For use Max Pidek Pharmaceuticals in combination with metronidazole: chronic gastritis in acute, peptic ulcer and duodenal ulcer in acute, associated with Helicobacter Pylori.
Uses of Mukinol in details
Mukinol is used to treat certain diseases of the respiratory tract and to relieve cough associated with thickened mucous.
Mukinol description
Each retard capsule contains Ambroxol hydrochloride 75 mg.
Each tablet contains Ambroxol hydrochloride 30 mg.
Each 5 mL of syrup contains Ambroxol hydrochloride 15 or 30 mg.
Each mL of syrup (infant drops) contains Ambroxol hydrochloride 6 mg.
Mukinol hydrochloride is trans-4-[(2-amino-3,5-dibromo-benzyl)amino] cyclohexanol hydrochloride.
It also contains the following excipients: Retard Capsules: Crospovidone collidon CL, carnauba wax, stearyl alcohol, magnesium stearate.
Tablets: Lactose, maize starch, colloidal silica, magnesium stearate.
Syrup: Purified water, sorbitol liquid, glycerol 85%, woodberry aroma (15 mg only), strawberry aroma (30 mg only), hydroxyethylcellulose, benzoic acid, acesulfame potassium, vanilla aroma.
Infant Drops: Hydroxyethylcellulose, sorbitol solution, glycerol 85%, sodium saccharin, pharma flavors, menthol, benzoic acid, propylene glycol.
Mukinol dosage
Sustained-Release Capsule: Adults and Children >12 years: 1 cap once daily after meal with plenty of liquid (sufficient supply of liquid supports the expectorant effect of Mukinol).
Mukinol SR capsule is not suitable for children <12 years.
Tablet: Adults and Children >12 years: 1 tab thrice daily for the first 2-3 days and then 1 tab twice daily or ½ tab thrice daily. Children 6-12 years: ½ tab 2-3 times a day.
Syrup: Adults and Children >12 years: 10 mL thrice daily during the first 2-3 days, them 10 mL twice daily or 5 mL thrice daily. Children 6-12 years: 5 mL 2-3 times a day; 2-5 years: 2.5 mL 3 times a day; <2 years: 2.5 mL 2 times a day.
DS Syrup: Adults and Children >12 years: 5 mL thrice daily for 2-3 days then 5 mL twice daily for 2.5 mL thrice daily. Children 6-12 years: 2.5 mL 2-3 times a day.
Infant Drops: Children 13-24 months: 1.25 mL twice a day; 7-12 months: 1 mL twice a day; ≤6 months: 0.5 mL twice a day.
Mukinol interactions
Amoxicillin may decrease the effectiveness of contraceptives for oral administration.
With the simultaneous use of Max Pidek Pharmaceuticals with bactericidal antibiotics (including aminoglycosides, cephalosporins, cycloserine, vancomycin, rifampicin) appears synergies; with bacteriostatic antibiotic (including macrolides, chloramphenicol, lincosamides, tetracyclines, sulphonamide) - antagonism.
Amoxicillin increases the effects of indirect anticoagulants inhibiting intestinal microflora, reduces the synthesis of vitamin K and prothrombin index.
Amoxicillin reduces the effect of drugs, in the process of metabolism that produce PABA.
Probenecid, diuretics, allopurinol, phenylbutazone, NSAIDs decrease the tubular secretion of amoxicillin, which can be accompanied by an increase in its concentration in blood plasma.
Antacids, glucosamine, laxatives, aminoglycosides, slow down and reduce, and ascorbic acid increases the absorption of amoxicillin.
With the combined use of amoxicillin and clavulanic acid pharmacokinetics of both components unchanged.
Mukinol side effects
Allergic reactions: urticaria, erythema, edema Quincke, rhinitis, conjunctivitis, rarely - fever, joint pain, eosinophilia, in rare cases - anaphylactic shock.
Side effects associated with chemotherapy effect: possible development of super-infection (particularly in patients with chronic diseases or low resistance of the organism).
With prolonged use at high doses: dizziness, ataxia, confusion, depression, peripheral neuropathy, seizures.
Mostly when Max Pidek Pharmaceuticals used in combination with metronidazole: nausea, vomiting, anorexia, diarrhea, constipation, epigastric pain, glossitis, stomatitis; rarely - hepatitis, pseudomembranous colitis, allergic reactions (urticaria, angioedema), interstitial nephritis, a violation of hematopoiesis.
Mostly when Max Pidek Pharmaceuticals used in combination with clavulanic acid: cholestatic jaundice, hepatitis, rarely - erythema multiforme, toxic epidermal necrolysis, exfoliative dermatitis.
Mukinol contraindications
Hypersensitivity to Mukinol hydrochloride or to any other excipients of Mukinol.
In case of rare hereditary conditions that may be incompatible with an excipient of Mukinol, the use of Mukinol is contraindicated.
Active ingredient matches for Mukinol:
Ambroxol in Indonesia.
List of Mukinol substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Mukex (Philippines) | |
| Mukex tab 30 mg 50's (Kusum Healthcare) | |
| Mukobron (Poland) | |
| Mukoflhem (Peru) | |
| Mukoral (Georgia, Turkey) | |
| Mukoral Pediatrik (Turkey) | |
| Munorm (India) | |
| Munorm Ambroxol15mg, Terbutaline1.25mg, Guaiphenesin50mg, Menthol2.5mg/5ml SYR / 100ml (Flamingo) | $ 0.53 |
| 100ml (Flamingo) | $ 0.53 |
| Munorm Ambroxol 15mg, Terbutaline 1.25mg, Guaiphenesin 50mg, Menthol 2.5mg/5ml SYR / 100ml (Flamingo) | $ 0.53 |
| MUNORM 50MG/1.25MG/15MG SYRUP 1 bottle / 100 ML syrup each (Flamingo) | $ 0.53 |
| MUNORM syr 100ml (Flamingo) | $ 0.53 |
| Munorm Syrup (Flamingo) | $ 0.53 |
| Musalten (Mexico) | |
| Solution; Oral; Ambroxol Hydrochloride 15 mg / 5 ml (Continentales) | |
| Musalten C | |
| Tablet, Film-Coated; Oral; Ambroxol Hydrochloride 30 mg | |
| Muscarin (India) | |
| Muscarin Ambroxol 15 mg, Terbutaline1.25 mg, Guaiphenesin 50 mg. SYR / 100ml (Sipra) | $ 0.43 |
| 100ml (Sipra) | $ 0.43 |
| MUSCARIN syr 100ml (Sipra) | $ 0.43 |
| Musco (Taiwan) | |
| Musco 30 mg x 1000's | |
| Musco 30 mg x 100 x 10's | |
| Musco 3 mg/1 mL x 1 mL | |
| Musco 3 mg/1 mL x 60 mL | |
| Musco 3 mg/1 mL x 100 mL | |
| Musco 3 mg/1 mL x 120 mL | |
| Musco 3 mg/1 mL x 1 gal | |
| Musocan (Thailand) | |
| Musocan 30 mg x 200's (Sriprasit) | |
| Mussibron (Dominican Republic) | |
| Musvan (Mexico) | |
| Mutech (India) | |
| Mutech Ambroxol hydrochloride 15 mg, Terbutaline sulphate 1.25 mg, Guaiphenesin 50 mg, Menthol2.5 mg/5 mL. SYR / 100ml (Pharma-Tech) | $ 0.46 |
| 100ml (Pharma-Tech) | $ 0.46 |
| MUTECH syr 100ml (Pharma-Tech) | $ 0.46 |
| Muxen (Venezuela) | |
| Muximed (Spain) | |
| Muxol (Chile, Colombia, France, Luxembourg, Peru, Romania, Switzerland, Tunisia) | |
| Dragee; Oral; Bisacodyl 10 mg (Andromaco) | |
| Injectable; Injection; Ambroxol Hydrochloride 15 mg / 2 ml (Andromaco) | |
| Solution; Oral; Ambroxol Hydrochloride 15 mg / 5 ml (Andromaco) | |
| Solution; Oral; Ambroxol Hydrochloride 30 mg / 5 ml (Andromaco) | |
| Tablet; Oral; Ambroxol Hydrochloride 30 mg (Andromaco) | |
| Muxol 30 mg x 30 Tablet (Andromaco) | |
| Muxol Flem Adultos (Colombia) | |
| Muxol Flem Niños (Colombia) | |
| Muxol Flem NiГ±os (Colombia) | |
| Muxol Fort (Tunisia) | |
| Muxol Infantil (Peru) | |
See 3105 substitutes for Mukinol | |
References
- PubChem. "ambroxol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "ambroxol". http://www.drugbank.ca/drugs/DB06742 (accessed September 17, 2018).
- MeSH. "Expectorants". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Mukinol are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Mukinol. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
