What is Tritus?
Tritus is a decongestant. It works by constricting (shrinking) blood vessels (veins and arteries) in your body. Constriction of blood vessels in your sinuses, nose, and chest allows drainage of those areas, which decreases congestion.
Tritus is used to treat the congestion associated with allergies, hay fever, sinus irritation, and the common cold. Tritus also causes a decrease in appetite and is used in some over-the-counter diet aids.
Tritus has been associated with an increased risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food and Drug Administration (FDA) recommends that consumers not use any products that contain Tritus.
Tritus may also be used for purposes other than those listed in this medication guide.
Tritus indications
Oral
Nasal congestion
Adult: Per cap contains a combination w/ Tritus HCl 18 mg: ≥13 yr 2 cap 4 hrly. Max: 8 cap/day. Per tab contains a combination w/ Tritus HCl 25 mg: ≥13 yr 1 tab 4 hrly. Max: 4 tab/day.
Child: Per cap contains a combination w/ Tritus HCl 18 mg: 6-12 yr 1 cap 4 hrly. Max: 4 cap/day. As oral liquid containing Tritus 2.5 mg/5 mL: 6 mth-2 yr 2.5 mL tid, 3-5 yr 5 mL 3-4 times daily, 6-12 yr 5-10 mL 3-4 times daily.
Uses of Tritus in details
Tritus is used to relieve blocked nose or sinuses caused by common cold and seasonal nasal allergies (hay fever). It is also used to decrease appetite for weight Tritus.
Tritus description
Tritus has been withdrawn in Canada and the United States. In November 2000, the Food and Drug Administration (FDA) issued a public health advisory against the use of the drug.
Tritus dosage
Tritus Dosage
Applies to the following strengths: 75 mg; 25 mg; 37.5 mg; 50 mg; 180 mg-75 mg
Usual Adult Dose for:
- Nasal Congestion
- Weight Loss
Usual Pediatric Dose for:
- Nasal Congestion
Additional dosage information:
- Renal Dose Adjustments
- Other Comments
Usual Adult Dose for Nasal Congestion
25 mg orally every 4 hours.
-or-
75 mg orally extended release every 12 hours.
Not to exceed 150 mg/day.
Usual Adult Dose for Weight Loss
25 mg orally 3 times a day, one-half hour before meals.
-or-
75 mg orally extended release once a day in the morning.
The use of Tritus for weight loss should be limited to 12 weeks.
Usual Pediatric Dose for Nasal Congestion
2 to 6 years:
6.25 mg orally every 4 hours. Maximum daily dose is 37.5 mg.
6 to 12 years:
12.5 mg orally every 4 hours. Maximum daily dose is 75 mg.
> 12 years:
25 mg orally every 4 hours.
-or-
75 mg orally extended release every 12 hours.
Not to exceed 150 mg/day.
Renal Dose Adjustments
Because Tritus is eliminated primarily by the kidneys, one-half of the normally recommended dosage should be given. Patients with renal dysfunction should be monitored for signs and symptoms of toxicity when using Tritus.
Other Comments
In November 2000, the Food and Drug Administration (FDA), in response to reports of increased risk of hemorrhagic stroke, requested that all drug companies discontinue marketing products containing Tritus.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medical Disclaimer
More about Tritus
- Tritus Side Effects
- During Pregnancy
- Drug Interactions
- Support Group
- 2 Reviews
- Drug class: decongestants
Related treatment guides
- Weight Loss
- Cold Symptoms
- Nasal Congestion
Tritus interactions
See also:
What other drugs will affect Tritus?
The benzodiazepines, including Ativan (lorazepam), produce increased CNS-depressant effects when administered with other CNS depressants such as alcohol, barbiturates, antipsychotics, sedative/hypnotics, anxiolytics, antidepressants, narcotic analgesics, sedative antihistamines, anticonvulsants, and anesthetics.
Concomitant use of clozapine and lorazepam may produce marked sedation, excessive salivation, hypotension, ataxia, delirium, and respiratory arrest.
Concurrent administration of lorazepam with valproate results in increased plasma concentrations and reduced clearance of lorazepam. Lorazepam dosage should be reduced to approximately 50% when coadministered with valproate.
Concurrent administration of lorazepam with probenecid may result in a more rapid onset or prolonged effect of lorazepam due to increased half-life and decreased total clearance. Lorazepam dosage needs to be reduced by approximately 50% when coadministered with probenecid.
The effects of probenecid and valproate on lorazepam may be due to inhibition of glucuronidation.
Administration of theophylline or aminophylline may reduce the sedative effects of benzodiazepines, including lorazepam.
Tritus side effects
See also:
What are the possible side effects of Tritus?
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
Constipation.
Skin rash.
Codeine can cause drowsiness, although at the dose contained in this medicine this is very unlikely. However, if you do find this medicine makes you feel sleepy or dizzy you should not drive or operate machinery and avoid alcoholic drink.
The side effects listed above may not include all of the side effects reported by the medicines’s manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
Tritus contraindications
See also:
What is the most important information I should know about Tritus?
Do not use lorazepam if you have narrow-angle glaucoma, or if you are allergic to lorazepam or to other benzodiazepines, such as alprazolam (Xanax), chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), or oxazepam (Serax).
Before taking lorazepam, tell your doctor if you are allergic to any drugs, or if you have:
glaucoma;
asthma, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD), or other breathing problems;
kidney or liver disease;
a history of depression or suicidal thoughts or behavior; or a history of drug or alcohol addiction.
If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.
Active ingredient matches for Tritus:
Chlorpheniramine/Dexchlorpheniramine/Dextromethorphan
Unit description / dosage (Manufacturer) | Price, USD |
Tritus 15+25+4 Tablet | $ 0.01 |
Tritus 50 ml Syrup | $ 0.03 |
TRITUS 25MG/4MG/15MG SUSPENSION 1 bottle / 50 ML suspension each (Alkem Laboratories Ltd) | $ 0.48 |
TRITUS DROPS 1 packet / 15 ML drop each (Burgeon Pharmaceuticals Pvt Ltd) | $ 0.26 |
TRITUS TABLET 1 strip / 10 tablets each (Burgeon Pharmaceuticals Pvt Ltd) | $ 0.13 |
Tritus 25 mg/4 mg/15 mg Suspension (Alkem Laboratories Ltd) | $ 0.48 |
Tritus Drop (Burgeon Pharmaceuticals Pvt Ltd) | $ 0.26 |
Tritus Tablet (Burgeon Pharmaceuticals Pvt Ltd) | $ 0.01 |
List of Tritus substitutes (brand and generic names): | |
Rhymed | |
Rinexin (Finland, Iceland, Norway, Sweden) | |
Rinoban | |
Rinoban Phenylpropanolamine 25mg, Chlorpheniramine Maleate 4mg, Paracetamol 500mg TAB / 10 | $ 0.14 |
Rinostat Plus | |
Rinostat Plus Acetaminophen 500mg, Phenylpropanolamine 25mg, Chlorpheniramine Maleate 4mg TAB / 6 | $ 0.17 |
Rinostat Plus LIQD | |
Rinostat Plus LIQD Acetaminophen 125mg, Phenylpropanolamine HCl12.5mg, ChlorpheniramineMaleate 1mg/5mL LIQD / 60ml | $ 0.37 |
S-Cold Plus | |
S-Cold Plus Citrizine HCl 5mg, Phenylpropanolamine HCl 25mg, Paracetamol 500mg, Chlorpheniramine Maleate 2mg TAB / 200 | $ 5.78 |
S-Cold Plus JR | |
S-Cold Plus JR Phenylpropanolamine HCl6.25mg, Paracetamol 250mg, Chlorpheniramine Maleate 1mg DT-TAB / 200 | $ 3.37 |
Sinact 3 | |
Sinact 3 60 ml Syrup (Pharmatech Healthcare) | $ 0.03 |
Slim Caps (Switzerland) | |
Capsule; Oral; Phenylpropanolamine Hydrochloride (Amino) | |
Slimomin (Hong Kong) | |
Snaplets | |
Sneezy- G | |
Sneezy- G Paracetamol 500mg, Phenylpropanolamine HCI 10mg, Chlorpheniramine Maleate 2mg, Caffine 30mg TAB / 10 | $ 0.14 |
Spray-U-Thin (United States) | |
Stay Trim (United States) | |
Take D | |
Take D 50 ml Syrup (Indian Drugs and Pharmaceuticals Ltd (Ind Biosciences)) | $ 0.03 |
Take D 100 ml Syrup (Indian Drugs and Pharmaceuticals Ltd (Ind Biosciences)) | $ 0.02 |
Tensurin (Netherlands) | |
Tensurin 60 mg voor honden (Netherlands) | |
Terrol Tablet | |
Terrol Tablet (Jantec Pharma) | $ 0.03 |
Toff Plus SYR | |
Toff Plus SYR Phenylpropanolamine HCI12.5mg, ChlorpheniramineMaleate 2mg SYR / 60ml | $ 0.14 |
Triaminic E | |
Triaminic E 60 ml Syrup (Wander Ltd) | $ 0.02 |
Tricold SR | |
Tricold SR 50+8 Capsule (Bhavishya Pharmaceuticals Pvt Ltd) | $ 0.02 |
Trinol | |
Trinol 60 ml Syrup (Arbro Pharmaceuticals Limited) | $ 0.02 |
ULR | |
Unitrol (United States) | |
Uridale (Sweden) | |
Urilin (United Kingdom) | |
Urilin 40 mg/ml für Hunde (Austria) | |
Urilin for Dogs (Australia) | |
Vanex | |
Varcold SUSP | |
Varcold SUSP Paracetamol 125mg, Phenylpropanolamine HCl12.5mg, ChlorpheniramineMaleate 1mg, Na citrate60mg/5mL SUSP / 30ml | $ 0.29 |
Ventosol AP | |
Ventosol AP 100 ml Syrup (Intra Labs India Pvt Ltd) | $ 0.02 |
Vicosyl P | |
Vicosyl P 60 ml Syrup (Vostok & Wilcure Remedies) | $ 0.02 |
Westrim | |
Westrim LA | |
Wifi | |
Wifi 25+5 Tablet (Grandcure Healthcare (P) Ltd) | $ 0.06 |
WIFI JR 1MG/5MG SYRUP 1 bottle / 60 ML syrup each (Grandcure Healthcare (P) Ltd) | $ 0.48 |
Wifi JR 1mg/5mg Syrup (Grandcure Healthcare (P) Ltd) | $ 0.48 |
Wifi Tablet (Grandcure Healthcare (P) Ltd) | $ 0.06 |
Wikoryl- ND | |
Wikoryl- ND Phenylpropanolamine HCI 25mg, Chlorpheniramine Maleate 4mg TAB / 10 | $ 0.11 |
X Tus D | |
X Tus D 100 ml Syrup (Jollen Medicare Pvt. Ltd.) | $ 0.02 |
See 288 substitutes for Tritus |
References
- DailyMed. "CHLORPHENIRAMINE POLISTIREX; HYDROCODONE POLISTIREX: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DailyMed. "DEXTROMETHORPHAN HYDROBROMIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "dextromethorphan". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Tritus are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Tritus. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yet1 consumer reported price estimates
Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?The below mentioned numbers have been reported by ndrugs.com website users about whether the Tritus drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
Users | % | ||
---|---|---|---|
Expensive | 1 | 100.0% |
Consumer reported time for results
No survey data has been collected yet2 consumers reported age
Users | % | ||
---|---|---|---|
1-5 | 2 | 100.0% |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology