Bromox Uses

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Bromox indications

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Bromox SYRUP indicated for cough associated with wheeziness (bronchospasm) and tenacious phlegm (sputum).

Uses of Bromox in details

Bromox is used to treat breathing difficulties caused by excessive mucus secretions in the air passages associated with respiratory tract infections.

Bromox description

Each tablet also contains lactose, maize or potato starch, gelatine and magnesium stearate as excipients.

The oral/inhalation solution also contains tartaric acid and methyl parahydroxybenzoate as excipients.

The syrup also contains tartaric acid, benzoic acid, sodium carboxymethylcellulose, glycerol, sorbitol solution, pharma flavor and ethanol as excipients.

Each capsule also contains lactose, cornstarch and magnesium stearate as excipients.

Bromox HCl is N-cyclohexyl-N-methyl-(2-amino-3,5-dibromobenzyl)amine hydrochloride.

Bromox dosage

Unless otherwise prescribed, the following doses are recommended:

Tablet: Adults and Children >12 years: 8 mg (1 tab) thrice daily; 6-12 years: 4 mg (½ tab) thrice daily; 2-6 years: 4 mg (½ tab) twice daily.

Oral Solution:

Adults and Children >12 years: 4 mL thrice daily; 6-12 years: 2 mL thrice daily; 2-6 years: 20 drops thrice daily; <2 years: 10 drops thrice daily.

Inhalation Solution (with aerosol apparatus): It is generally recommended to warm inhalation solution to body temperature before inhalation. Patients with bronchial asthma may be advised to commencing inhalation after they have taken their regular bronchospasmolytic therapy.

Adults: 4 mL. Children >12 years: 2 mL; 6-12 years: 1 mL; 2-6 years: 10 drops; <2 years: 5 drops. All doses to be taken twice daily.

The solution may be diluted 1:1 in physiological saline solution. In order to avoid precipitation, the solution should be inhaled immediately after mixing. The combined administration of inhalation and oral application intensifies the effect, and is especially suited for the commencement of treatment in cases where the full effect is to be reached quickly.

Syrup: Adults and Children >12 years: 5 ml (1 tsp) thrice daily.

At commencement of treatment, it may be necessary to increase the total daily dose up to 48 mg in adults.

The syrup is sugar-free and therefore suitable for diabetics and small children.

Ampoule: Severe cases, before and after surgical intervention: 1 amp SC, IM or IV (duration of injection: 2-3 min) 2-3 times daily.

Capsule: Adults: 1 cap 3 times daily.

It is recommended for the initial phase of treatment usually lasting not more than a week.

Patients being treated with Bromox should be notified of an expected increase in the flow of secretions.

Bromox interactions

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A reduction in dose of cardiac glycosides (e.g. digitalis) and quinidine might become necessary in patients suffering from congestive cardiac failure because of the positive inotropic effect of orciprenaline sulphate.

Bromox SYRUP should not be administered concomitantly with beta-blocking agents, due to orciprenaline’s reversal of anti-hypertensive action.

The concomitant use of other sympathomimetic agents should be carefully controlled to avoid potentiation of effects.

Bromox side effects

Bromox’s pharmacological action may lead to gastric irritation. A transient rise in serum aminotransferase values have been reported due to Bromox.

Orciprenaline sulphate, as a sympathomimetic agent, may precipitate a wide range of adverse effects. Side-effects include fear; anxiety, restlessness, tremor, insomnia, confusion, irritability, weakness and psychotic states. Appetite may be reduced and nausea and vomiting may occur. A rise in blood pressure which may produce cerebral haemorrhage and pulmonary oedema, tachycardia and cardiac arrhythmias, anginal pain, palpitations, and cardiac arrest. Hypotension with dizziness and fainting and flushing may occur. Other effects that may occur include difficulty in micturition and urinary retention; dyspnoea; weakness; headache; disturbances of glucose metabolism; sweating and hypersalivation. Muscle cramps or twitching or unpleasant taste may occur.

Bromox contraindications

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Bromox SYRUP is contra-indicated in patients with known hypersensitivity to sympathomimetic amines or any of the other ingredients; hypertrophic obstructive cardiomyopathy; and tachyarrhythmia.

Sympathomimetics, such as orciprenaline sulphate, may interact with monoamine oxidase inhibitors (MAOI), and therefore Bromox SYRUP should not be given to patients receiving such treatment or within 14 days of MAOI treatment termination.

Safety in pregnancy and lactation has not been established.

Active ingredient matches for Bromox:

Bromhexine in Venezuela.

Amoxicillin

Bromhexine Hcl

Bromhexine hydrochloride in Venezuela.


Unit description / dosage (Manufacturer)Price, USD
BROMOX Liquid / 125mg per 5ml / 60ml units (Talent Laboratories)$ 0.28
BROMOX Liquid / 125mg per 5ml / 30ml units (Talent Laboratories)$ 0.21
BROMOX Capsule/ Tablet / 250mg - 8mg / 10 units (Talent Laboratories)$ 0.42
BROMOX Capsule/ Tablet / 125mg / 10 units (Talent Laboratories)$ 0.23
BROMOX Capsule/ Tablet / 500mg / 10 units (Talent Laboratories)$ 0.72
Bromox 250+8 Capsule$ 0.04
Bromox 8 mg Tablet$ 0.01
Bromox 500 mg Capsule$ 0.07
Bromox 250 mg Capsule$ 0.04
Bromox 60 ml Syrup$ 0.04
BROMOX 125MG TABLET 1 strip / 10 tablets each (Talent Healthcare)$ 0.15
BROMOX 250MG CAPSULE 1 strip / 10 capsules each (Talent Healthcare)$ 0.43
BROMOX 500MG CAPSULE 1 strip / 10 capsules each (Talent Healthcare)$ 0.72
Bromox 125mg Tablet (Talent Healthcare)$ 0.02
Bromox 250mg Capsule (Talent Healthcare)$ 0.04
Bromox 500mg Capsule (Talent Healthcare)$ 0.07

List of Bromox substitutes (brand and generic names):

Bromoxy 250+8 Tablet (Medipol Pharmaceuticals India Pvt. Ltd.)$ 0.05
Bromoxykan 250+8 Tablet (Kansas Laboratories Pvt. Ltd.)$ 0.04
Bromoxyl KT 125+4 Tablet (Concept Pharmaceuticals Ltd.)$ 0.03
Bromso 8 mg x 1, 000's (T. O. Chemicals)
Bromso 4 mg/5 mL x 60 mL (T. O. Chemicals)
Bromso elixir 4 mg/5 mL 60 mL x 1's (T. O. Chemicals)
Bromso tab 8 mg 1000's (T. O. Chemicals)
Bromxine 8 mg x 1, 000's (General Drugs House)
Bromxine 8 mg x 1000's (General Drugs House)
Bromxine 4 mg/5 mL x 60 mL x 1's (General Drugs House)
Bromxine tab 8 mg 1000's (General Drugs House)
Bromxine Atlantic 8 mg x 1, 000's (Atlantic Lab)
Bromxine Atlantic tab 8 mg 1000's (Atlantic Lab)
Broncho Solvin 100+8+2.5 Tablet (IPCA Laboratories Ltd.)$ 0.02
Bronchodian 100 ml Syrup (Meri Odin Life Sciences)$ 0.02
Bronchofit 100 ml Suspension (Pharmatech Healthcare)$ 0.04
Bronchofit 60 ml Suspension (Pharmatech Healthcare)$ 0.05
BRONCHOFIT syr 100ml (Pharmatech Healthcare)$ 0.54
BRONCHOFIT syr 60ml (Pharmatech Healthcare)$ 0.39
Broncholik 100 ml Syrup (SPS Medipol Pvt. Ltd.)$ 0.03
Drops; Oral; Anise Oil 0.25 mg; Bromhexine Hydrochloride 8 mg; Eucalyptus Oil 0.25 mg; Fennel Oil 0.75 mg; Menthol 1.5 mg; Origanum Oil 0.25 mg; Peppermint Oil 0.25 mg / g (Vitasan)
Bronchosan 25 ml - 1 Drops (Vitasan)$ 10.40
Bronchosol-BR 2+8 Tablet (Tosc International Pvt Ltd.)$ 0.01
Bronclear 8 mg x 1, 000's (Polipharm)
Broncoff 60 ml Syrup (Kylsans Laboratories Ltd)$ 0.04
Broncogard 100 ml Syrup (Nimbles Biotech Pvt Ltd)$ 0.05

References

  1. DailyMed. "AMOXICILLIN; CLAVULANATE POTASSIUM: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "amoxicillin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. PubChem. "bromhexine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Bromox are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Bromox. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet


Consumer reported price estimates

No survey data has been collected yet


1 consumer reported time for results

To what extent do I have to use Bromox before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 1 month and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Bromox. To get the time effectiveness of using Bromox drug by other patients, please click here.
Users%
1 month1
100.0%


1 consumer reported age

Users%
30-451
100.0%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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