Dexbro indications
Dexbro hydrochloride SYRUP indicated for cough associated with wheeziness (bronchospasm) and tenacious phlegm (sputum).
Uses of Dexbro in details
Dexbro is used to treat breathing difficulties caused by excessive mucus secretions in the air passages associated with respiratory tract infections.
Dexbro description
Each tablet also contains lactose, maize or potato starch, gelatine and magnesium stearate as excipients.
The oral/inhalation solution also contains tartaric acid and methyl parahydroxybenzoate as excipients.
The syrup also contains tartaric acid, benzoic acid, sodium carboxymethylcellulose, glycerol, sorbitol solution, pharma flavor and ethanol as excipients.
Each capsule also contains lactose, cornstarch and magnesium stearate as excipients.
Dexbro HCl is N-cyclohexyl-N-methyl-(2-amino-3,5-dibromobenzyl)amine hydrochloride.
Dexbro dosage
Unless otherwise prescribed, the following doses are recommended:
Tablet: Adults and Children >12 years: 8 mg (1 tab) thrice daily; 6-12 years: 4 mg (½ tab) thrice daily; 2-6 years: 4 mg (½ tab) twice daily.
Oral Solution:
Adults and Children >12 years: 4 mL thrice daily; 6-12 years: 2 mL thrice daily; 2-6 years: 20 drops thrice daily; <2 years: 10 drops thrice daily.Inhalation Solution (with aerosol apparatus): It is generally recommended to warm inhalation solution to body temperature before inhalation. Patients with bronchial asthma may be advised to commencing inhalation after they have taken their regular bronchospasmolytic therapy.
Adults: 4 mL. Children >12 years: 2 mL; 6-12 years: 1 mL; 2-6 years: 10 drops; <2 years: 5 drops. All doses to be taken twice daily.
The solution may be diluted 1:1 in physiological saline solution. In order to avoid precipitation, the solution should be inhaled immediately after mixing. The combined administration of inhalation and oral application intensifies the effect, and is especially suited for the commencement of treatment in cases where the full effect is to be reached quickly.
Syrup: Adults and Children >12 years: 5 ml (1 tsp) thrice daily.
At commencement of treatment, it may be necessary to increase the total daily dose up to 48 mg in adults.
The syrup is sugar-free and therefore suitable for diabetics and small children.
Ampoule: Severe cases, before and after surgical intervention: 1 amp SC, IM or IV (duration of injection: 2-3 min) 2-3 times daily.
Capsule: Adults: 1 cap 3 times daily.
It is recommended for the initial phase of treatment usually lasting not more than a week.
Patients being treated with Dexbro should be notified of an expected increase in the flow of secretions.
Dexbro interactions
A reduction in dose of cardiac glycosides (e.g. digitalis) and quinidine might become necessary in patients suffering from congestive cardiac failure because of the positive inotropic effect of orciprenaline sulphate.
Dexbro hydrochloride SYRUP should not be administered concomitantly with beta-blocking agents, due to orciprenaline’s reversal of anti-hypertensive action.
The concomitant use of other sympathomimetic agents should be carefully controlled to avoid potentiation of effects.
Dexbro side effects
Dexbro’s pharmacological action may lead to gastric irritation. A transient rise in serum aminotransferase values have been reported due to Dexbro.
Orciprenaline sulphate, as a sympathomimetic agent, may precipitate a wide range of adverse effects. Side-effects include fear; anxiety, restlessness, tremor, insomnia, confusion, irritability, weakness and psychotic states. Appetite may be reduced and nausea and vomiting may occur. A rise in blood pressure which may produce cerebral haemorrhage and pulmonary oedema, tachycardia and cardiac arrhythmias, anginal pain, palpitations, and cardiac arrest. Hypotension with dizziness and fainting and flushing may occur. Other effects that may occur include difficulty in micturition and urinary retention; dyspnoea; weakness; headache; disturbances of glucose metabolism; sweating and hypersalivation. Muscle cramps or twitching or unpleasant taste may occur.
Dexbro contraindications
Dexbro hydrochloride SYRUP is contra-indicated in patients with known hypersensitivity to sympathomimetic amines or any of the other ingredients; hypertrophic obstructive cardiomyopathy; and tachyarrhythmia.
Sympathomimetics, such as orciprenaline sulphate, may interact with monoamine oxidase inhibitors (MAOI), and therefore Dexbro hydrochloride SYRUP should not be given to patients receiving such treatment or within 14 days of MAOI treatment termination.
Safety in pregnancy and lactation has not been established.
Active ingredient matches for Dexbro:
Ammonium Chloride/Dextromethorphan
| Unit description / dosage (Manufacturer) | Price, USD |
| Dexbro 120 ml Syrup | $ 0.02 |
| Dexbro 60 ml Syrup | $ 0.03 |
| Dexbro Syrup (Eisen Pharmaceutical Co Pvt Ltd) | $ 0.57 |
List of Dexbro substitutes (brand and generic names): | |
| Descongel Tos (Colombia) | |
| Dexolut (Indonesia) | |
| Dexolut 8 mg x 10 x 10's (Dexa) | $ 1.36 |
| Dexolut 10 mg/5 mL x 60 mL x 1's (Dexa) | $ 0.72 |
| Dexolut 4 mg/5 mL x 100 mL x 1's (Dexa) | $ 0.39 |
| Dexthro-BR | |
| Dexthro-BR 100 ml Syrup (Adbio Organics Pvt Ltd) | $ 0.03 |
| Dextonil (Venezuela) | |
| Dibroxin (Mexico) | |
| Disco (Taiwan) | |
| Disco 8 mg | |
| Disol (Thailand) | |
| Injectable; Injection; Sodium Acetate 2 g / l; Sodium Chloride 6 g (Invomed) | |
| Disol 8 mg x 100's (Invomed) | |
| Disol 8 mg x 1, 000's (Invomed) | |
| Disol 4 mg/5 mL x 60 mL (Invomed) | |
| Disol 8 mg/5 mL x 60 mL (Invomed) | |
| Disol Diclofenac diethylammonium1.16 % w/w, menthol 5 % w/w, methylsalicylate 10 % w/w. GEL / 30g (Invomed) | $ 0.63 |
| DISOL topical gel 30g (Invomed) | $ 0.63 |
| Disol elixir 4 mg/5 mL 60 mL x 1's (Invomed) | |
| Disol Forte elixir 8 mg/5 mL 60 mL x 1's (Invomed) | |
| Disol tab 8 mg 100's (Invomed) | |
| Disol tab 8 mg 1000's (Invomed) | |
| Disolmux (Mexico) | |
| Disolvan (Vietnam) | |
| Disolvan 8 mg x 10 Blister x 10 Tablet | |
| Disolvan 8 mg x 10 Blister x 20 Tablet | |
| Disolvan 1 Bottle 100 mL | |
| Disolvan 80 mg/100 mL x 1 Bottle 100 mL | |
| DM X | |
| DM X 100 ml Syrup (Mars Therapeutics & Chemicals Ltd) | $ 0.01 |
| Dosulvon (Vietnam) | |
| Dosulvon 8 mg x 1 Bottle 200 Tablet | |
| Dosulvon 8 mg x 1 Bottle 500 Tablet | |
| DR Koff Tablet | |
| DR Koff Tablet (Intas Laboratories Pvt Ltd) | $ 0.02 |
| DR. Kuff | |
| DR. Kuff 4+2+2 Tablet (Apple Biotech) | $ 0.01 |
| Dr.Koff (India) | |
| Dr.Koff Dextromethorphan 10 mg, Guaiphenesin 100 mg, Bromhexine hydrochloride 8 mg, Chlorpheniramine maleate 2 mg. TAB / 10 | $ 0.23 |
| 10's | $ 0.23 |
| Drometox (Venezuela) | |
| Drydex (India) | |
| Drydex Bromhexine hydrochloride 4 mg, Menthol 2.5 mg, Dextromethorphan hydrobromide5 mg, Ammonium chloride 50mg/5 mL. SYR / 100ml (Nectar Lifesciences Ltd (Neccare)) | $ 0.59 |
| Drydex Bromhexine hydrochloride 4 mg, Menthol 2.5 mg, Dextromethorphan hydrobromide5 mg, Ammonium chloride 50mg/5 mL. SYR / 50ml (Nectar Lifesciences Ltd (Neccare)) | $ 0.35 |
| 100ml (Nectar Lifesciences Ltd (Neccare)) | $ 0.59 |
| 50ml (Nectar Lifesciences Ltd (Neccare)) | $ 0.35 |
| Drydex 100 ml Syrup (Nectar Lifesciences Ltd (Neccare)) | $ 0.03 |
| Drydex 50 ml Syrup (Nectar Lifesciences Ltd (Neccare)) | $ 0.03 |
| DRYDEX syr 100ml (Nectar Lifesciences Ltd (Neccare)) | $ 0.59 |
| DRYDEX syr 50ml (Nectar Lifesciences Ltd (Neccare)) | $ 0.35 |
| Drydex T | |
| Drydex T 50 ml Syrup (Nectar Life Sciences Ltd.) | $ 0.04 |
| Drydex T 100 ml Syrup (Nectar Life Sciences Ltd.) | $ 0.03 |
See 1882 substitutes for Dexbro | |
References
- DailyMed. "DEXTROMETHORPHAN HYDROBROMIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DailyMed. "AMMONIUM CHLORIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "dextromethorphan". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Dexbro are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Dexbro. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yet2 consumers reported age
| Users | % | ||
|---|---|---|---|
| 30-45 | 2 | 100.0% | |
Consumer reviews
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Information checked by Dr. Sachin Kumar, MD Pharmacology
