Diclamin Uses

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Diclamin indications

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For the treatment of functional disturbances of gastrointestinal motility eg, irritable bowel syndrome and renal and biliary colic. As with other antispasmodics, Diclamin has limited efficacy in the treatment of these disorders and should be used only if other measures (eg, diet) have been of little or no benefit.

Diclamin has been used alone or in combination with phenobarbital in the treatment of infant colic and acute enterocolitis but lacks substantial evidence of efficacy in these conditions. Infant colic is considered a benign and self-limiting condition.

Diclamin description

A muscarinic antagonist used as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It does have some local anesthetic properties and is used in gastrointestinal, biliary, and urinary tract spasms.

Diclamin dosage

Oral

Gastrointestinal tract spasm

Adult: 10-20 mg tid.

Child: 2-12 yr: 10 mg tid; 6 mth-2 yr: 5-10 mg 3-4 times daily.

Elderly:

Intramuscular

Gastrointestinal tract spasm

Adult: 20 mg 4 times a day given only for 1-2 days. Replace with oral therapy as soon as possible.

Diclamin interactions

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The following agents may increase certain actions or side effects of anticholinergic drugs. amantadine antiarrhythmic agents of class (e.g. quinidine), antihistamines antipsychotic agents (e.g. phenothiazines), benzodiazepines. MAO inhibitors, narcotic analgesics (e.g., meperidine), nitrates and nitrites, sympathomimetic agents, tricyclic antidepressants, and other drugs having anticholinergic activity.

Anticholinergics antagonize the effects of antiglaucoma agents. Anticholinergic drugs in the presence of increased intraocular pressure may be hazardous when taken concurrently with agents such as corti costeroids..

Anticholinergic agents may affect gastrointestinal absorption of various drugs, such as slowly dissolving dosage forms of digoxin; increased serum digoxin concentrations may result.

Anticholinergic drugs may antagonize the effects of the drugs that alter gastrointestinal motility, such as metoclopramide. Because antacids may interfere with the absorption of anticholinergic agents, simultaneous use of these drugs should be avoided.

The inhibiting effects of anticholinergic drugs on gastric hydrochloric acid secretion are antagonized by agents used to treat achlorhydria and those used to test gastric secretion.

Diclamin side effects

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Dryness of mouth w/ difficulty in swallowing & talking, thirst, reduced bronchial secretions, mydriasis w/ cycloplegia & photophobia, flushing & dryness of the skin, transient bradycardia w/ palpitations & arrhythmias, difficulty in micturition, constipation.

Diclamin contraindications

Diclamin should not be given to patients with obstructive uropathy, obstructive disease of the GIT, ulcerative colitis, reflux esophagitis, hypersensitivity to Diclamin HCl and nursing mothers.

Active ingredient matches for Diclamin:

Dicycloverine in Taiwan.


Unit description / dosage (Manufacturer)Price, USD
Diclamin 10 mg

List of Diclamin substitutes (brand and generic names):

Diclomine 10 tube x 3 mL
DICOMIN Capsule/ Tablet / 20mg - 500mg / 10 units (Radicura Pharmaceutical Pvt. Ltd.)$ 0.17
10's (Radicura Pharmaceutical Pvt. Ltd.)$ 0.17
Dicomin Paracetamol 500 mg, Dicyclomine hydrochloride 20mg. TAB / 10 (Radicura Pharmaceutical Pvt. Ltd.)$ 0.17
Dicomin 20+500 Radicura Tablet (Radicura Pharmaceutical Pvt. Ltd.)$ 0.02
Dicomin 20+500 Tablet (Radicura Pharmaceutical Pvt. Ltd.)$ 0.02
DICOMIN 20MG/500MG TABLET 1 strip / 10 tablets each (Radicura Pharmaceutical Pvt. Ltd.)$ 0.17
DICOMIN tab 10's (Radicura Pharmaceutical Pvt. Ltd.)$ 0.17
Dicomin 20 mg/500 mg Tablet (Radicura Pharmaceutical Pvt. Ltd.)$ 0.02
100 capsule in 1 bottle
1000 capsule in 1 bottle
100 tablet in 1 bottle
1000 tablet in 1 bottle
Dicyclomine Hydrochloride capsule 10 mg/1 (State of Florida DOH Central Pharmacy (US))
Dicyclomine Hydrochloride tablet 20 mg/1 (Clinical Solutions Wholesale (US))
Dicyclomine Hydrochloride syrup 10 mg/mL (Entera Health, Inc. (US))
Dicyclomine Hydrochloride solution 10 mg/5mL (Atlantic Biologicals Corps (US))
Dicyclomine Hydrochloride tablet 10 mg/1 (State of Florida DOH Central Pharmacy (US))
Dicyclomine Hydrochloride injection 10 mg/mL (West Ward Pharmaceuticals Corp. (US))
Dicymine 10 mg x 1, 000's (Christo)
Dicymine Co 3.6 L (Christo)
Dicymine 15 mg x 1, 000's (Christo)
Dilomin 10 mg x 100's (Am-europharma)$ 13.52
Dilomin 10 mg/5 mL x 60 mL (Am-europharma)$ 0.73
Capsule; Oral; Dicyclomine Hydrochloride 10 mg (Icn)
Kuetonbily 10 mg
Loverin 0.6 mg/1 g x 10 g
Loverin 0.6 mg/1 g x 25 g

Reviews

The results of a survey conducted on ndrugs.com for Diclamin are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Diclamin. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

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Consumer reported useful

No survey data has been collected yet


Consumer reported price estimates

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Consumer reported time for results

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1 consumer reported age

Users%
30-451
100.0%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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