What is Hydrotride?
Hydrotride is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.
Hydrotride is also used to treat fluid retention (edema) that is caused by congestive heart failure, severe liver disease (cirrhosis), kidney disease, or treatment with a steroid or hormone medicine.
Hydrotride is a thiazide diuretic (water pill). It is used to help reduce the amount of water in the body by increasing the flow of urine. It may also be used for other conditions as determined by your doctor.
Hydrotride is available only with your doctor's prescription.
Hydrotride indications
Hydrotride Capsules are indicated in the management of hypertension either as the sole therapeutic agent, or in combination with other antihypertensives. Unlike potassium sparing combination diuretic products, Hydrotride Capsules may be used in those patients in whom the development of hyperkalemia cannot be risked, including patients taking ACE inhibitors.
Usage in Pregnancy: The routine use of diuretics in an otherwise healthy woman is inappropriate and exposes mother and fetus to unnecessary hazard. Diuretics do not prevent development of toxemia of pregnancy, and there is no satisfactory evidence that they are useful in the treatment of developed toxemia.
Edema during pregnancy may arise from pathological causes or from the physiologic and mechanical consequences of pregnancy. Diuretics are indicated in pregnancy when edema is due to pathologic causes, just as they are in the absence of pregnancy. Dependent edema in pregnancy resulting from restriction of venous return by the expanded uterus is properly treated through elevation of the lower extremities and use of support hose; use of diuretics to lower intravascular volume in this case is illogical and unnecessary. There is hypervolemia during normal pregnancy which is harmful to neither the fetus nor the mother (in the absence of cardiovascular disease), but which is associated with edema, including generalized edema in the majority of pregnant women. If this edema produces discomfort, increased recumbency will often provide relief. In rare instances this edema may cause extreme discomfort which is not relieved by rest. In these cases a short course of diuretics may provide relief and may be appropriate.
How should I use Hydrotride?
Use Hydrotride capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Hydrotride capsules by mouth with or without food.
- If you take colestipol or cholestyramine for high cholesterol, ask your doctor or pharmacist how to take it with Hydrotride capsules.
- Hydrotride capsules may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.
- If you miss a dose of Hydrotride capsules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Hydrotride capsules.
Uses of Hydrotride in details
This medication is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Hydrotride is a "water pill" (diuretic) that causes you to make more urine. This helps your body get rid of extra salt and water.
This medication also reduces extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, or kidney disease. This can lessen symptoms such as shortness of breath or swelling in your ankles or feet.
How to use Hydrotride
Take this medication by mouth as directed by your doctor, usually once daily in the morning with or without food. It is best to avoid taking this medication within 4 hours of your bedtime to prevent having to get up to urinate.
The dosage is based on your medical condition and response to treatment.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick.
Cholestyramine and colestipol can decrease the absorption of Hydrotride. If you are taking either of these drugs, take them at least 4 hours before or after taking Hydrotride.
Tell your doctor if your condition does not improve or if it worsens (for example, your blood pressure readings increase).
Hydrotride description
Each film-coated tablet contains losartan potassium 50 mg and Hydrotride 12.5 mg.
Losartan potassium is 2-Butyl-4-chloro-1-[p-o-1H-tetrazol-5-yl-phenyl)benzyl]imidazole-5-methanol, potassium. Its empirical formula is C22H22ClKN6O and molecular weight is 461.
Hydrotride is 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide. Its empirical formula is C7H8ClN3O4S2 and molecular weight is 297.7.
Hydrotride dosage
Hydrotride Dosage
Generic name: Hydrotride 12.5mg
Dosage form: capsule, gelatin coated
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
For Control of Hypertension: The adult initial dose of Hydrotride is one capsule given once daily whether given alone or in combination with other antihypertensives. Total daily doses greater than 50 mg are not recommended.
More about Hydrotride (Hydrotride)
- Side Effects
- During Pregnancy or Breastfeeding
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- En Espanol
- 0 Reviews - Add your own review/rating
- Generic Availability
Consumer resources
- Hydrotride
- Hydrotride (Advanced Reading)
- Other brands: Aquazide H
Professional resources
- Hydrotride (AHFS Monograph)
- Hydrotride (FDA)
Related treatment guides
- Diabetes Insipidus
- Edema
- High Blood Pressure
- Nephrocalcinosis
- Osteoporosis
Hydrotride interactions
See also:
What other drugs will affect Hydrotride?
DIAMOX®. modifies phenytoin metabolism with increased serum levels of phenytoin. This may increase or enhance the occurrence of osteomalacia in some patients receiving chronic phenytoin therapy. Caution is advised in patients receiving chronic concomitant therapy.
By decreasing the gastrointestinal absorption of primidone, DIAMOX may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. Caution is advised when beginning, discontinuing, or changing the dose of DIAMOX in patients receiving primidone.
Because of possible additive effects with other carbonic anhydrase inhibitors, concomitant use is not advisable.
Hydrotride may increase the effects of other folic acid antagonists.
Hydrotride may increase or decrease blood glucose levels. Consideration should be taken in patients being treated with antidiabetic agents.
Hydrotride decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect.
Hydrotride reduces urinary excretion of quinidine and may enhance its effect.
Hydrotride may prevent the urinary antiseptic effect of methenamine.
Hydrotride increases lithium excretion and the lithium may be decreased.
Hydrotride and sodium bicarbonate used concurrently increases the risk of renal calculus formation.
Hydrotride may elevate cyclosporine levels.
Hydrotride side effects
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What are the possible side effects of Hydrotride?
The adverse reactions associated with Hydrotride have been shown to be dose related. In controlled clinical trials, the adverse events reported with doses of 12.5 mg Hydrotride once daily were comparable to placebo. The following adverse reactions have been reported for doses of Hydrotride 25 mg and greater and, within each category, are listed in the order of decreasing severity.
Body as a whole: Weakness.
Cardiovascular: Hypotension including orthostatic hypotension (may be aggravated by alcohol, barbiturates, narcotics or antihypertensive drugs).
Digestive: Pancreatitis, jaundice (intrahepatic cholestatic jaundice), diarrhea, vomiting, sialadenitis, cramping, constipation, gastric irritation, nausea, anorexia.
Hematologic: Aplastic anemia, agranulocytosis, leukopenia, hemolytic anemia, thrombocytopenia.
Hypersensitivity: Anaphylactic reactions, necrotizing angiitis (vasculitis and cutaneous vasculitis), respiratory distress including pneumonitis and pulmonary edema, photosensitivity, fever, urticaria, rash, purpura.
Metabolic: Electrolyte imbalance, hyperglycemia, glycosuria, hyperuricemia.
Musculoskeletal: Muscle Spasm.
Nervous System/Psychiatric: Vertigo, paresthesia, dizziness, headache, restlessness.
Renal: Renal failure, renal dysfunction, interstitial nephritis.
Skin: Erythema multiforme including Stevens-Johnson syndrome, exfoliative dermatitis including toxic epidermal necrolysis, alopecia.
Special Senses: Transient blurred vision, xanthopsia.
Urogenital: Impotence.
Whenever adverse reactions are moderate or severe, thiazide dosage should be reduced or therapy withdrawn.
Hydrotride contraindications
See also:
What is the most important information I should know about Hydrotride?
You should not use this medication if you are allergic to Hydrotride or if you are unable to urinate.
Before using this medication, tell your doctor if you have liver disease, kidney disease, glaucoma, asthma or allergies, gout, diabetes, or if you are allergic to sulfa drugs or penicillin.
Avoid drinking alcohol, which can increase some of the side effects of Hydrotride.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.
There are many other drugs that can interact with Hydrotride. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.
Active ingredient matches for Hydrotride:
Hydrochlorothiazide in Singapore.
| Unit description / dosage (Manufacturer) | Price, USD |
| Hydrotride 50 mg x 1's | |
List of Hydrotride substitutes (brand and generic names): | |
| Hydrothide | |
| Hydrozide (Malaysia, Singapore, Thailand, United States) | |
| Hydrozide 50 mg x 500's (Douglas) | |
| Hydrozide 50 mg x 1000's (Douglas) | |
| Tablets; Oral; Hydrochlorothiazide 50 mg (Douglas) | |
| Hydrozide Atlantic (Hong Kong) | |
| Hydrozide Atlantic 50 mg x 500's (Atlantic Lab) | |
| Hydrozide Atlantic tab 50 mg 500's (Atlantic Lab) | |
| Hydrozide Medicine Products (Thailand) | |
| Hydrozide Medicine Products 50 mg x 1, 000's | |
| Hypodehydra (Bulgaria) | |
| Hypothiazid (Bulgaria, Estonia, Georgia, Hungary, Latvia, Lithuania, Russian Federation) | |
| Tablet; Oral; Hydrochlorothiazide 100 mg (Chinoin) | |
| Tablet; Oral; Hydrochlorothiazide 25 mg (Chinoin) | |
| Generic Microzide 25mg - 45 Tablets (Chinoin) | $ 31.99 |
| Generic Microzide 25mg - 90 Tablets (Chinoin) | $ 49.99 |
| Generic Microzide 25mg - 180 Tablets (Chinoin) | $ 79.99 |
| Hypothiazid 100mg - 20 Tablets (Chinoin) | $ 8.40 |
| Hypothiazid 25mg - 20 Tablets (Chinoin) | $ 10.40 |
| Tablets; Oral; Hydrochlorothiazide 100 mg (Chinoin) | |
| Tablets; Oral; Hydrochlorothiazide 25 mg (Chinoin) | |
| Hypothiazid 100 mg (Hungary) | |
| Hypothiazid 25 mg (Hungary) | |
| Hypothiazide (Georgia) | |
| Hypotiazid | |
| Tablet; Oral; Hydrochlorothiazide 100 mg | |
| Tablet; Oral; Hydrochlorothiazide 25 mg | |
| Tablets; Oral; Hydrochlorothiazide 100 mg | |
| Tablets; Oral; Hydrochlorothiazide 25 mg | |
| Hytaz (Philippines) | |
| Hytaz 12.5 mg x 200's (Therapharma) | $ 0.11 |
| Hytaz 25 mg x 200's (Therapharma) | $ 0.14 |
| Hytaz tab 12.5 mg 200's (Therapharma) | $ 0.11 |
| Hytaz tab 25 mg 200's (Therapharma) | $ 28.58 |
| Hytel H | |
| Hytel H 40+12.5 Tablet (East West Pharma) | $ 0.08 |
| HYTEL H 40MG/12.5MG TABLET 1 strip / 10 tablets each (East West Pharma) | $ 0.83 |
| Hytel H 40mg/12.5mg Tablet (East West Pharma) | $ 0.08 |
| Hytrid | |
| Hyzide (India) | |
| Hyzide 12.5mg TAB / 10 (East West Pharma) | $ 0.13 |
| Hyzide 25mg TAB / 10 (East West Pharma) | $ 0.21 |
| 12.5 mg x 10's (East West Pharma) | $ 0.13 |
| 25 mg x 10's (East West Pharma) | $ 0.21 |
| Hyzide 25 mg Tablet (East West Pharma) | $ 0.02 |
| Hyzide 12.5 mg Tablet (East West Pharma) | $ 0.01 |
| HYZIDE tab 12.5 mg x 10's (East West Pharma) | $ 0.13 |
| HYZIDE tab 25 mg x 10's (East West Pharma) | $ 0.21 |
| Icn-Hythide | |
| Idrodiuvis (Italy) | |
See 1222 substitutes for Hydrotride | |
References
- DailyMed. "AMLODIPINE BESYLATE; HYDROCHLOROTHIAZIDE; OLMESARTAN MEDOXOMIL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "hydrochlorothiazide". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "hydrochlorothiazide". http://www.drugbank.ca/drugs/DB00999 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Hydrotride are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Hydrotride. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
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Information checked by Dr. Sachin Kumar, MD Pharmacology
