Lincomycin HCL Tai Yu Uses

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What is Lincomycin HCL Tai Yu?

Lincomycin HCL Tai Yu is an antibiotic that fights bacteria.

Lincomycin HCL Tai Yu is used to treat severe bacterial infections in people who cannot use penicillin antibiotics.

Lincomycin HCL Tai Yu is used only for a severe infection. This medicine will not treat a viral infection such as the common cold or flu.

Lincomycin HCL Tai Yu may also be used for purposes not listed in this medication guide.

Lincomycin HCL Tai Yu indications

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Lincomycin HCL Tai Yu Sterile Solution is indicated in the treatment of serious infections due to susceptible strains of streptococci, pneumococci, and staphylococci. Its use should be reserved for penicillin-allergic patients or other patients for whom, in the judgment of the physician, a penicillin is inappropriate. Because of the risk of antibiotic-associated pseudomembranous colitis, as described in Warnings, before selecting Lincomycin HCL Tai Yu the physician should consider the nature of the infection and the suitability of less toxic alternatives (e.g., erythromycin).

Bacteriologic studies should be performed to determine the causative organisms and their susceptibility to Lincomycin HCL Tai Yu.

Indicated surgical procedures should be performed in conjunction with antibiotic therapy.

Lincomycin HCL Tai Yu has been demonstrated to be effective in the treatment of staphylococcal infections resistant to other antibiotics and susceptible to Lincomycin HCL Tai Yu. Staphylococcal strains resistant to Lincomycin HCL Tai Yu have been recovered; culture and susceptibility studies should be done in conjunction with therapy with Lincomycin HCL Tai Yu. In the case of macrolides, partial but not complete cross-resistance may occur. The drug may be administered concomitantly with other antimicrobial agents when indicated.

Lincomycin HCL Tai Yu is not indicated in the treatment of minor bacterial infections or viral infections.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Lincomycin HCL Tai Yu and other antibacterial drugs, Lincomycin HCL Tai Yu should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

How should I use Lincomycin HCL Tai Yu?

Use Lincomycin HCL Tai Yu as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Lincomycin HCL Tai Yu.

Uses of Lincomycin HCL Tai Yu in details

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Lincomycin HCL Tai Yu is used in treatment of bacterial infections.

Lincomycin HCL Tai Yu description

Each mL of Lincomycin HCL Tai Yu Sterile Solution contains Lincomycin hydrochloride equivalent to Lincomycin HCL Tai Yu 300 mg.

Lincomycin HCL Tai Yu sterile solution contains Lincomycin hydrochloride which is the monohydrated salt of Lincomycin HCL Tai Yu, a substance produced by the growth of a member of the lincolnensis group of Streptomyces lincolnensis (Fam. Streptomycetaceae).

The chemical name for Lincomycin HCL Tai Yu hydrochloride is Methyl 6, 8-dideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrolidinecarboxamido)-1-thio-D-erythro-α-D-galacto-octopyranoside monohydrochloride monohydrate. Its molecular formula is C18H34N2O6S.HCl. H2O and the molecular weight is 461.01.

Lincomycin HCL Tai Yu hydrochloride is a white or practically white, crystalline powder and is odorless or has a faint odor. Its solutions are acid and are dextrorotatory. Lincomycin HCL Tai Yu hydrochloride is freely soluble in water; soluble in dimethylformamide and very slightly soluble in acetone.

Excipients/Inactive Ingredients: Benzyl alcohol 9.45 mg added as preservative.

Lincomycin HCL Tai Yu dosage

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Lincomycin HCL Tai Yu Dosage

Generic name: Lincomycin HCL Tai Yu HYDROCHLORIDE 300mg in 1mL

Dosage form: injection, solution

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

If significant diarrhea occurs during therapy, this antibacterial should be discontinued.

INTRAMUSCULAR

Adults

Serious infections—600 mg (2 mL) intramuscularly every 24 hours. More severe infections—600 mg (2 mL) intramuscularly every 12 hours or more often.

Pediatric patients over 1 month of age

Serious infections—one intramuscular injection of 10 mg/kg (5 mg/lb) every 24 hours. More severe infections—one intramuscular injection of 10 mg/kg (5 mg/lb) every 12 hours or more often.

INTRAVENOUS

Adults

The intravenous dose will be determined by the severity of the infection. For serious infections doses of 600 mg of Lincomycin HCL Tai Yu (2 mL of Lincomycin HCL Tai Yu) to 1 gram are given every 8 to 12 hours. For more severe infections these doses may have to be increased. In life-threatening situations daily intravenous doses of as much as 8 grams have been given.

Intravenous doses are given on the basis of 1 gram of Lincomycin HCL Tai Yu diluted in not less than 100 mL of appropriate solution and infused over a period of not less than one hour.

Dose Vol. Diluent Time
600 mg 100 mL 1 hr
1 gram 100 mL 1 hr
2 grams 200 mL 2 hr
3 grams 300 mL 3 hr
4 grams 400 mL 4 hr

These doses may be repeated as often as required to the limit of the maximum recommended daily dose of 8 grams of Lincomycin HCL Tai Yu.

Pediatric patients over 1 month of age

10 to 20 mg/kg/day (5 to 10 mg/lb/day) depending on the severity of the infection may be infused in divided doses as described above for adults.

NOTE: Severe cardiopulmonary reactions have occurred when this drug has been given at greater than the recommended concentration and rate.

SUBCONJUNCTIVAL INJECTION

0.25 mL (75 mg) injected subconjunctivally will result in ocular fluid levels of antibacterial (lasting for at least 5 hours) with MICs sufficient for most susceptible pathogens.

Patients with diminished renal function

When therapy with Lincomycin HCL Tai Yu is required in individuals with severe impairment of renal function, an appropriate dose is 25 to 30% of that recommended for patients with normally functioning kidneys.

More about Lincomycin HCL Tai Yu (Lincomycin HCL Tai Yu)

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Lincomycin HCL Tai Yu interactions

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What other drugs will affect Lincomycin HCL Tai Yu?

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BCG (Intravesical): Antibiotics may diminish the therapeutic effect of BCG (Intravesical). Avoid combination

BCG Vaccine (Immunization): Antibiotics may diminish the therapeutic effect of BCG Vaccine (Immunization). Monitor therapy

Cholera Vaccine: Antibiotics may diminish the therapeutic effect of Cholera Vaccine. Management: Avoid cholera vaccine in patients receiving systemic antibiotics, and within 14 days following the use of oral or parenteral antibiotics. Avoid combination

Doxofylline: Lincomycin HCL Tai Yu may increase the serum concentration of Doxofylline. Monitor therapy

Erythromycin (Systemic): May diminish the therapeutic effect of Lincomycin HCL Tai Yu. Avoid combination

Kaolin: May decrease the absorption of Lincosamide Antibiotics. Monitor therapy

Lactobacillus and Estriol: Antibiotics may diminish the therapeutic effect of Lactobacillus and Estriol. Monitor therapy

Mecamylamine: Lincosamide Antibiotics may enhance the neuromuscular-blocking effect of Mecamylamine. Avoid combination

Neuromuscular-Blocking Agents: Lincosamide Antibiotics may enhance the neuromuscular-blocking effect of Neuromuscular-Blocking Agents. Monitor therapy

Sodium Picosulfate: Antibiotics may diminish the therapeutic effect of Sodium Picosulfate. Management: Consider using an alternative product for bowel cleansing prior to a colonoscopy in patients who have recently used or are concurrently using an antibiotic. Consider therapy modification

Typhoid Vaccine: Antibiotics may diminish the therapeutic effect of Typhoid Vaccine. Only the live attenuated Ty21a strain is affected. Management: Vaccination with live attenuated typhoid vaccine (Ty21a) should be avoided in patients being treated with systemic antibacterial agents. Use of this vaccine should be postponed until at least 3 days after cessation of antibacterial agents. Consider therapy modification

Lincomycin HCL Tai Yu side effects

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What are the possible side effects of Lincomycin HCL Tai Yu?

Applies to Lincomycin HCL Tai Yu: capsule, solution

In addition to its needed effects, some unwanted effects may be caused by Lincomycin HCL Tai Yu (the active ingredient contained in Lincomycin HCL Tai Yu). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking Lincomycin HCL Tai Yu:

More common:

Less common:

Note: Some of the above side effects may also occur up to several weeks after you Stop taking Lincomycin HCL Tai Yu.

Minor Side Effects

Some of the side effects that can occur with Lincomycin HCL Tai Yu may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:

Less common:

Lincomycin HCL Tai Yu contraindications

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What is the most important information I should know about Lincomycin HCL Tai Yu?

Before receiving Lincomycin HCL Tai Yu, tell your doctor if you have asthma or allergies, a stomach or intestinal disorder such as colitis, liver or kidney disease, or epilepsy or other seizure disorder.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

Serious side effects of Lincomycin HCL Tai Yu include fever, chills, body aches, flu symptoms, white patches or sores inside your mouth or on your lips, severe blistering or peeling skin rash, feeling like you might pass out, easy bruising or bleeding, unusual weakness, or urinating less than usual or not at all.

Active ingredient matches for Lincomycin HCL Tai Yu:

Lincomycin in Taiwan.


List of Lincomycin HCL Tai Yu substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Linconit - INJ / 2ml$ 0.14
Lincono 300 mg/1 mL x 10 mL x 10's (Milano)
Lincophar 500 mg x 60's (Pharos)$ 37.24
Lincopi 600 mg/2 mL x 10 tube 2 mL
Lincople 600 mg/2 mL x 10 Bottle
Lincosa 300 mg/1 mL x 10 mL x 1's (ZHPL (Sayona))
300 mg x 1ml (ZHPL (Sayona))$ 0.11
Lincosa 300mg AMP / 1ml (ZHPL (Sayona))$ 0.11
LINCOSA inj 300 mg x 1ml (ZHPL (Sayona))$ 0.11
Lincosa 300 mg inj 2 mL x 50 x 1's (ZHPL (Sayona))
Lincosa 300 mg inj 10 mL x 10 x 1's (ZHPL (Sayona))
Lincostad 500 mg x 10 Blister x 10 Tablet
LINCOWOCK 1MG INJECTION 1 vial / 1 ML injection each (Wockhardt Ltd)$ 0.09
LINCOWOCK 2MG INJECTION 1 vial / 2 ML injection each (Wockhardt Ltd)$ 0.16
Lincowock 2mg Injection (Wockhardt Ltd)$ 0.08
Lincozin 250mg CAP / 10 (Taj Pharma)$ 0.70
Lincozin 500mg CAP / 10 (Taj Pharma)$ 1.12
Lincozin 125mg/mL SYR / 60ml (Taj Pharma)$ 0.55

References

  1. PubChem. "lincomycin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "lincomycin". http://www.drugbank.ca/drugs/DB01627 (accessed September 17, 2018).
  3. MeSH. "Protein Synthesis Inhibitors". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

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