Locomin indications
Articular syndrome (rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout), degenerative and chronic inflammatory diseases of musculoskeletal system (osteochondrosis, osteoarthritis, periartropatii), post-traumatic inflammation of soft tissue and musculoskeletal system (sprains, bruises). Pain in the spine, neuralgia, myalgia, arthralgia, pain and inflammation after surgery or injury, pain in gout, migraine, algomenorrhea, pain with Bursitis, proctitis, colic (biliary and renal), pain in infectious and inflammatory diseases of ENT organs.
For local use: the inhibition of miosis during surgery for cataract prevention of cystoid macular edema associated with removal and lens implantation, inflammatory eye non-infectious nature, post-traumatic inflammation in penetrating and nonpenetrating wound of the eyeball.
Uses of Locomin in details
It is used to relieve pain and swelling of joints (osteoarthritis), swelling of the small joints of hands and feet (rheumatoid arthritis), arthritis that mainly affect the spine (ankylosing spondylitis).
Locomin description
Locomin also contains the following excipients: Medium chain triglycerides, hard fat, gelatin, D-sorbitol, concentrated glycerin, titanium dioxide, yellow no. 5, red no. 40 and purified water.
Locomin dosage
FC tab: Usual Dose: 100 mg twice daily.
Renal Insufficiency: There is no evidence that the dosage of Locomin needs to be modified in patients with mild renal impairment, but as with other NSAIDs, caution should be exercised.
Hepatic Insufficiency: There is some evidence that the dose of Locomin should be reduced in patients with hepatic impairment and it is suggested that an initial dose of 100 mg be used.
SR tab: Adults: 1 tablet daily.
Children: There are no clinical data on the use of Locomin in children.
Gel: Adults: Gently rub 2-4 g (a circular shaped mass approximately 2-2.5 cm in diameter) 3-4 times daily. Maximum Daily Dose: 16 g. Maximum Weekly Dose: 112 g. A period of at least 4 hrs should be left between applications. The dose should not be applied >4 times in a 24-hr period. After application, the hands should be washed unless this is the treated site. Do not use for >14 days unless recommended by the physician.
Locomin interactions
Lithium: Locomin may increase plasma concentrations of lithium.
Cardiac Glycosides: NSAIDs may exacerbate cardiac failure and reduce the glomerular filtration rate in patients receiving glycosides due to increase plasma glycoside (including digoxin) levels.
Diuretics: Locomin, like other NSAIDs, may inhibit the activity of diuretics. Diuretics can increase the risk of nephrotoxicity of NSAIDs.
Anticoagulants: Like other NSAIDs, Locomin may enhance the activity of anticoagulants.
Methotrexate: Since NSAIDs may increase plasma levels, resulting in increased toxicity, caution should be exercised if NSAIDs and methotrexate are administered within 24 hrs of each other.
Mifepristone: NSAIDs should not be used for 8-12 days after mifepristone administration as NSAIDs can reduce the effect of mifepristone.
Other NSAIDs and Steroids: Concomitant therapy with aspirin, other NSAIDs and steroids may increase the frequency of adverse reactions, including the risk of gastrointestinal bleeding.
Cyclosporin: Cyclosporin nephrotoxicity may be increased by the effect of NSAIDs on renal prostaglandins.
Locomin side effects
The majority of adverse reactions reported have been reversible and of a minor nature. The most frequent are gastrointestinal disorders, in particular dyspepsia, abdominal pain, nausea and diarrhea, and occasional occurrence of dizziness. Dermatological complaints including pruritus and rash, and abnormal hepatic enzyme and serum creatinine levels have also been reported.
If serious adverse reactions occur, Locomin should be withdrawn.
Inform the physician or pharmacist in case of adverse effects related to Locomin used.
Locomin contraindications
Hypersensitivity to Locomin, acetylsalicylic acid or to any of the excipients of Locomin.
FC tab/SR tab: Active or history of recurrent peptic ulcer/haemorrhage (≥2 distinct episodes of proven ulceration or bleeding); NSAIDs are contraindicated in patients who have previously shown hypersensitivity reactions (eg, asthma, rhinitis, angioedema or urticaria) in response to ibuprofen, aspirin or other NSAIDs; severe heart, hepatic and renal failure; history of gastrointestinal (GI) bleeding or perforation, related to previous NSAIDs therapy.
Gel: Patients with or without chronic asthma in whom attacks of asthma, urticaria or acute rhinitis are precipitated by aspirin or other NSAIDs; concomitant use of other products containing Locomin; concomitant use of oral NSAIDs.
Do not use in children and adolescents <14 years.
Use in pregnancy & lactation: FC tab/SR tab: NSAIDs should not be used during pregnancy or labour unless the potential benefit to the patient outweighs the potential risk to the fetus.
In limited studies available, NSAIDs can appear in the breast milk in very low concentrations. NSAIDs should, if possible, be avoided when breastfeeding.
Gel: Since no experience has been acquired with Locomin gel in pregnancy or lactation, it is not recommended for use in these circumstances.
Active ingredient matches for Locomin:
Aceclofenac in Switzerland.
List of Locomin substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Locoace | |
| Locoace 100mg Tablet (Alchemist Life Science Ltd) | $ 0.02 |
| Lofens (Bangladesh) | |
| Loflam (Oman) | |
| Loflam 15 mg x 30's | |
| Loflam 15 mg x 100's | |
| Lycee-TH (India) | |
| Lycee-TH Aceclofenac 100 mg, Thiocolchicoside 8 mg TAB / 10 (Leemed) | $ 2.17 |
| 10's (Leemed) | $ 2.17 |
| LYCEE-TH tab 10's (Leemed) | $ 2.17 |
| Maclo (Bangladesh) | |
| Mahanac (India) | |
| Mahanac 100mg TAB / 10 (Zuventus (Zuvista)) | $ 0.24 |
| Mahanac 200mg TAB / 10 (Zuventus (Zuvista)) | $ 0.64 |
| 100 mg x 10's (Zuventus (Zuvista)) | $ 0.24 |
| 200 mg x 10's (Zuventus (Zuvista)) | $ 0.64 |
| MAHANAC 100MG TABLET 1 strip / 10 tablets each (Zuventus (Zuvista)) | $ 0.36 |
| MAHANAC 100MG TABLET 1 strip / 4 tablets each (Zuventus (Zuvista)) | $ 0.23 |
| MAHANAC 200MG TABLET SR 1 strip / 10 tablet srs each (Zuventus (Zuvista)) | $ 0.45 |
| MAHANAC TABLET MR 1 strip / 10 tablet mrs each (Zuventus (Zuvista)) | $ 0.16 |
| MAHANAC tab 100 mg x 10's (Zuventus (Zuvista)) | $ 0.24 |
| MAHANAC tab 200 mg x 10's (Zuventus (Zuvista)) | $ 0.64 |
| Mahanac 200mg Tablet SR (Zuventus (Zuvista)) | $ 0.05 |
| Mahanac NA Tablet MR (Zuventus (Zuvista)) | $ 0.02 |
| MAHANAC PLUS | |
| MAHANAC PLUS TABLET 1 strip / 10 tablets each (Zuventus Healthcare Ltd) | $ 0.33 |
| MAHANEC | |
| MAHANEC Capsule/ Tablet / 100mg / 10 units (Emcure Pharmaceuticals) | $ 0.23 |
| Meinuofen (China) | |
| Mervan (Bangladesh) | |
| MICRONAC (India) | |
| 100 mg x 10's (Micro HC) | $ 0.28 |
| Micronac 100mg TAB / 10 (Micro HC) | $ 0.28 |
| MICRONAC EYE DROP 1 packet / 5 ML eye drop each (Micro HC) | $ 1.54 |
| MICRONAC tab 100 mg x 10's (Micro HC) | $ 0.28 |
| Micronac 100mg TAB / 10 (Micro HC) | $ 0.28 |
| Micronac 0.1% w/v Eye Drop (Micro HC) | $ 1.69 |
| MICRONAC GEL (India) | |
| 30g (Micro HC) | $ 0.66 |
| Micronac Gel Aceclofenac1.5%w/w, MethylSalicylate10%w/w, Menthol5%w/w, LinseedOil3%w/w, Capsicin0.01%w/w GEL / 30g (Micro HC) | $ 0.66 |
| Micronac Gel Aceclofenac 1.5%w/w, MethylSalicylate 10%w/w, Menthol 5%w/w, LinseedOil 3%w/w, Capsicin 0.01%w/w GEL / 30g (Micro HC) | $ 0.66 |
| MICRONAC GEL topical gel 30g (Micro HC) | $ 0.66 |
| Micronac Gel Aceclofenac 1.5%w/w, MethylSalicylate 10%w/w, Menthol 5%w/w, LinseedOil 3%w/w, Capsicin 0.01%w/w GEL / 30g (Micro HC) | $ 0.66 |
| MICRONAC-SR (India) | |
| 200 mg x 10's (Micro HC) | $ 0.42 |
| Micronac-SR 200mg TAB / 10 (Micro HC) | $ 0.42 |
| MICRONAC-SR tab 200 mg x 10's (Micro HC) | $ 0.42 |
| Micronac-SR 200mg TAB / 10 (Micro HC) | $ 0.42 |
| Mobenac (Georgia) | |
| Mobenac FC tab 100 mg 10's (Alkem Lab) | $ 4.40 |
| Mobenac FC tab 100 mg 50's (Alkem Lab) | |
| MOBIRIDE-SR (India) | |
| 200 mg x 10's (Merck) | $ 0.48 |
See 2091 substitutes for Locomin | |
References
- PubChem. "Aceclofenac". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "Aceclofenac". http://www.drugbank.ca/drugs/DB06736 (accessed September 17, 2018).
- MeSH. "Anti-Inflammatory Agents, Non-Steroidal". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Locomin are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Locomin. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yet2 consumers reported time for results
To what extent do I have to use Locomin before I begin to see changes in my health conditions?As part of the reports released by ndrugs.com website users, it takes 5 days and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Locomin. To get the time effectiveness of using Locomin drug by other patients, please click here.
| Users | % | ||
|---|---|---|---|
| 5 days | 1 | 50.0% | |
| 2 days | 1 | 50.0% | |
3 consumers reported age
| Users | % | ||
|---|---|---|---|
| 30-45 | 1 | 33.3% | |
| > 60 | 1 | 33.3% | |
| 1-5 | 1 | 33.3% | |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
