Mucoaricodil indications
For use Max Pidek Pharmaceuticals as monotherapy and in combination with clavulanic acid: an infectious-inflammatory diseases caused by susceptible microorganisms, including bronchitis, pneumonia, tonsillitis, pyelonephritis, urethritis, infections of the gastrointestinal tract, gynecological infections, infections of the skin and soft tissue, listeria, leptospirosis, gonorrhea.
For use Max Pidek Pharmaceuticals in combination with metronidazole: chronic gastritis in acute, peptic ulcer and duodenal ulcer in acute, associated with Helicobacter Pylori.
Uses of Mucoaricodil in details
Mucoaricodil is used to treat certain diseases of the respiratory tract and to relieve cough associated with thickened mucous.
Mucoaricodil description
Each retard capsule contains Ambroxol 75 mg.
Each tablet contains Ambroxol 30 mg.
Each 5 mL of syrup contains Ambroxol 15 or 30 mg.
Each mL of syrup (infant drops) contains Ambroxol 6 mg.
Mucoaricodil is trans-4-[(2-amino-3,5-dibromo-benzyl)amino] cyclohexanol hydrochloride.
It also contains the following excipients: Retard Capsules: Crospovidone collidon CL, carnauba wax, stearyl alcohol, magnesium stearate.
Tablets: Lactose, maize starch, colloidal silica, magnesium stearate.
Syrup: Purified water, sorbitol liquid, glycerol 85%, woodberry aroma (15 mg only), strawberry aroma (30 mg only), hydroxyethylcellulose, benzoic acid, acesulfame potassium, vanilla aroma.
Infant Drops: Hydroxyethylcellulose, sorbitol solution, glycerol 85%, sodium saccharin, pharma flavors, menthol, benzoic acid, propylene glycol.
Mucoaricodil dosage
Sustained-Release Capsule: Adults and Children >12 years: 1 cap once daily after meal with plenty of liquid (sufficient supply of liquid supports the expectorant effect of Mucoaricodil).
Mucoaricodil SR capsule is not suitable for children <12 years.
Tablet: Adults and Children >12 years: 1 tab thrice daily for the first 2-3 days and then 1 tab twice daily or ½ tab thrice daily. Children 6-12 years: ½ tab 2-3 times a day.
Syrup: Adults and Children >12 years: 10 mL thrice daily during the first 2-3 days, them 10 mL twice daily or 5 mL thrice daily. Children 6-12 years: 5 mL 2-3 times a day; 2-5 years: 2.5 mL 3 times a day; <2 years: 2.5 mL 2 times a day.
DS Syrup: Adults and Children >12 years: 5 mL thrice daily for 2-3 days then 5 mL twice daily for 2.5 mL thrice daily. Children 6-12 years: 2.5 mL 2-3 times a day.
Infant Drops: Children 13-24 months: 1.25 mL twice a day; 7-12 months: 1 mL twice a day; ≤6 months: 0.5 mL twice a day.
Mucoaricodil interactions
Amoxicillin may decrease the effectiveness of contraceptives for oral administration.
With the simultaneous use of Max Pidek Pharmaceuticals with bactericidal antibiotics (including aminoglycosides, cephalosporins, cycloserine, vancomycin, rifampicin) appears synergies; with bacteriostatic antibiotic (including macrolides, chloramphenicol, lincosamides, tetracyclines, sulphonamide) - antagonism.
Amoxicillin increases the effects of indirect anticoagulants inhibiting intestinal microflora, reduces the synthesis of vitamin K and prothrombin index.
Amoxicillin reduces the effect of drugs, in the process of metabolism that produce PABA.
Probenecid, diuretics, allopurinol, phenylbutazone, NSAIDs decrease the tubular secretion of amoxicillin, which can be accompanied by an increase in its concentration in blood plasma.
Antacids, glucosamine, laxatives, aminoglycosides, slow down and reduce, and ascorbic acid increases the absorption of amoxicillin.
With the combined use of amoxicillin and clavulanic acid pharmacokinetics of both components unchanged.
Mucoaricodil side effects
Allergic reactions: urticaria, erythema, edema Quincke, rhinitis, conjunctivitis, rarely - fever, joint pain, eosinophilia, in rare cases - anaphylactic shock.
Side effects associated with chemotherapy effect: possible development of super-infection (particularly in patients with chronic diseases or low resistance of the organism).
With prolonged use at high doses: dizziness, ataxia, confusion, depression, peripheral neuropathy, seizures.
Mostly when Max Pidek Pharmaceuticals used in combination with metronidazole: nausea, vomiting, anorexia, diarrhea, constipation, epigastric pain, glossitis, stomatitis; rarely - hepatitis, pseudomembranous colitis, allergic reactions (urticaria, angioedema), interstitial nephritis, a violation of hematopoiesis.
Mostly when Max Pidek Pharmaceuticals used in combination with clavulanic acid: cholestatic jaundice, hepatitis, rarely - erythema multiforme, toxic epidermal necrolysis, exfoliative dermatitis.
Mucoaricodil contraindications
Hypersensitivity to Mucoaricodil or to any other excipients of Mucoaricodil.
In case of rare hereditary conditions that may be incompatible with an excipient of Mucoaricodil, the use of Mucoaricodil is contraindicated.
Active ingredient matches for Mucoaricodil:
Ambroxol in Italy.
Ambroxol hydrochloride in Italy.
List of Mucoaricodil substitutes (brand and generic names) | Sort by popularity |
Unit description / dosage (Manufacturer) | Price, USD |
Mucoangin 20mg (Austria, Hungary, Luxembourg) | |
Mucoastomari (Japan) | |
Mucobar-S Syrup (India) | |
Mucobar-S Syrup Ambroxol 30 mg, Guaiphenesin100 mg, Salbutamol 2 mg, Menthol 1 mg. SYR / 100ml (Symbiotic) | $ 0.54 |
100ml (Symbiotic) | $ 0.54 |
MUCOBAR-S SYRUP syr 100ml (Symbiotic) | $ 0.54 |
Mucobiotic (Peru) | |
Mucobron Forte (Argentina) | |
Mucobron Forte 100's (Medi-Rx) | $ 19.63 |
Mucobron Forte cap 100's (Medi-Rx) | $ 19.63 |
Mucobroncol (Peru) | |
Mucobrox (Thailand) | |
Mucobrox 30 mg x 50 x 10's | |
Mucobrox 30 mg x 500's | |
Mucobrox 30 mg/5 mL x 60 mL | |
Mucobroxol (El Salvador, Guatemala, Honduras, Malta, Nicaragua, Panama) | |
Mucobroxol SR (Egypt) | |
Mucobulin (Japan) | |
Mucocid (Ecuador) | |
Mucoclean (Brazil) | |
Mucoclear (Singapore) | |
Mucoclear 30 mg x 50 x 10's (Sunward) | |
Mucoclear tab 30 mg 50 x 10's (Sunward) | |
Mucodic (Thailand) | |
Mucodic 30 mg x 1, 000's (Medicine products) | |
Mucodic 30 mg/5 mL x 60 mL (Medicine products) | |
Mucodic 30 mg/5 mL x 1 gal (Medicine products) | |
Mucodos (Dominican Republic) | |
Mucodrenol (Portugal) | |
Mucoform (Georgia) | |
MUCOFORM TABLET 1 strip / 10 tablets each (Ajanta Pharma Ltd) | $ 0.28 |
Mucoform 60mg Tablet (Ajanta Pharma Ltd) | $ 0.03 |
Mucoform Syrup (Georgia) | |
Mucokil (Japan, Taiwan) | |
Mucokil 15 mg x 100's | |
Mucolan (Thailand) | |
Mucolax (Thailand) | |
Mucolax 30 mg x 500's | |
Mucolax 30 mg x 50 x 10's | |
Mucolax 30 mg/5 mL x 60 mL x 12's | |
Mucolax 30 mg/5 mL x 60 mL x 50's | |
Mucolen (Czech Republic, Slovakia) | |
Mucolica (Indonesia) | |
Mucolica 30 mg x 100's (Ikapharmindo) | $ 12.75 |
Mucolica 15 mg/5 mL x 60 mL x 24's (Ikapharmindo) | $ 2.25 |
Mucolisin (Bulgaria, Ecuador, Malta) | |
Mucolisin 15mg/5ml (Bulgaria) | |
Mucolisin 30mg/5ml (Bulgaria) | |
Mucolite (Bahrain, Iraq, Jordan, Kuwait, Lebanon, Libya, Nigeria, Oman, Qatar, Saudi Arabia, Sri Lanka, Sudan, Syria, United Arab Emirates, Yemen) | |
MUCOLITE Drops / 7.5mg per ml / 15ml units (Dr. Reddy's) | $ 0.18 |
MUCOLITE Capsule/ Tablet / 30mg / 10 units (Dr. Reddy's) | $ 0.18 |
MUCOLITE Liquid / 30mg per 5ml / 100ml units (Dr. Reddy's) | $ 0.48 |
See 3216 substitutes for Mucoaricodil |
References
- PubChem. "ambroxol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "ambroxol". http://www.drugbank.ca/drugs/DB06742 (accessed September 17, 2018).
- MeSH. "Expectorants". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
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Information checked by Dr. Sachin Kumar, MD Pharmacology