What is Naldec?
Naldec is a decongestant. It works by constricting (shrinking) blood vessels (veins and arteries) in your body. Constriction of blood vessels in your sinuses, nose, and chest allows drainage of those areas, which decreases congestion.
Naldec is used to treat the congestion associated with allergies, hay fever, sinus irritation, and the common cold. Naldec also causes a decrease in appetite and is used in some over-the-counter diet aids.
Naldec has been associated with an increased risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food and Drug Administration (FDA) recommends that consumers not use any products that contain Naldec.
Naldec may also be used for purposes other than those listed in this medication guide.
Naldec indications
influenza symptoms, cough
Uses of Naldec in details
Naldec is used to relieve blocked nose or sinuses caused by common cold and seasonal nasal allergies (hay fever). It is also used to decrease appetite for weight Naldec.
Naldec description
Naldec has been withdrawn in Canada and the United States. In November 2000, the Food and Drug Administration (FDA) issued a public health advisory against the use of the drug.
Naldec dosage
Naldec Dosage
Applies to the following strengths: 75 mg; 25 mg; 37.5 mg; 50 mg; 180 mg-75 mg
Usual Adult Dose for:
- Nasal Congestion
- Weight Loss
Usual Pediatric Dose for:
- Nasal Congestion
Additional dosage information:
- Renal Dose Adjustments
- Other Comments
Usual Adult Dose for Nasal Congestion
25 mg orally every 4 hours.
-or-
75 mg orally extended release every 12 hours.
Not to exceed 150 mg/day.
Usual Adult Dose for Weight Loss
25 mg orally 3 times a day, one-half hour before meals.
-or-
75 mg orally extended release once a day in the morning.
The use of Naldec for weight loss should be limited to 12 weeks.
Usual Pediatric Dose for Nasal Congestion
2 to 6 years:
6.25 mg orally every 4 hours. Maximum daily dose is 37.5 mg.
6 to 12 years:
12.5 mg orally every 4 hours. Maximum daily dose is 75 mg.
> 12 years:
25 mg orally every 4 hours.
-or-
75 mg orally extended release every 12 hours.
Not to exceed 150 mg/day.
Renal Dose Adjustments
Because Naldec is eliminated primarily by the kidneys, one-half of the normally recommended dosage should be given. Patients with renal dysfunction should be monitored for signs and symptoms of toxicity when using Naldec.
Other Comments
In November 2000, the Food and Drug Administration (FDA), in response to reports of increased risk of hemorrhagic stroke, requested that all drug companies discontinue marketing products containing Naldec.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medical Disclaimer
More about Naldec
- Naldec Side Effects
- During Pregnancy
- Drug Interactions
- Support Group
- 2 Reviews
- Drug class: decongestants
Related treatment guides
- Weight Loss
- Cold Symptoms
- Nasal Congestion
Naldec interactions
See also:
What other drugs will affect Naldec?
The benzodiazepines, including Ativan (lorazepam), produce increased CNS-depressant effects when administered with other CNS depressants such as alcohol, barbiturates, antipsychotics, sedative/hypnotics, anxiolytics, antidepressants, narcotic analgesics, sedative antihistamines, anticonvulsants, and anesthetics.
Concomitant use of clozapine and lorazepam may produce marked sedation, excessive salivation, hypotension, ataxia, delirium, and respiratory arrest.
Concurrent administration of lorazepam with valproate results in increased plasma concentrations and reduced clearance of lorazepam. Lorazepam dosage should be reduced to approximately 50% when coadministered with valproate.
Concurrent administration of lorazepam with probenecid may result in a more rapid onset or prolonged effect of lorazepam due to increased half-life and decreased total clearance. Lorazepam dosage needs to be reduced by approximately 50% when coadministered with probenecid.
The effects of probenecid and valproate on lorazepam may be due to inhibition of glucuronidation.
Administration of theophylline or aminophylline may reduce the sedative effects of benzodiazepines, including lorazepam.
Naldec side effects
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What are the possible side effects of Naldec?
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
Constipation.
Skin rash.
Codeine can cause drowsiness, although at the dose contained in this medicine this is very unlikely. However, if you do find this medicine makes you feel sleepy or dizzy you should not drive or operate machinery and avoid alcoholic drink.
The side effects listed above may not include all of the side effects reported by the medicines’s manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
Naldec contraindications
See also:
What is the most important information I should know about Naldec?
Do not use lorazepam if you have narrow-angle glaucoma, or if you are allergic to lorazepam or to other benzodiazepines, such as alprazolam (Xanax), chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), or oxazepam (Serax).
Before taking lorazepam, tell your doctor if you are allergic to any drugs, or if you have:
glaucoma;
asthma, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD), or other breathing problems;
kidney or liver disease;
a history of depression or suicidal thoughts or behavior; or a history of drug or alcohol addiction.
If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.
Active ingredient matches for Naldec:
Phenylpropanolamine HCl in Philippines.
Phenylpropanolamine hydrochloride in Philippines.
| Unit description / dosage (Manufacturer) | Price, USD |
| Naldec 12.5 mg/5 mL x 60 mL | |
| Naldec 6.25 mg/1 mL x 15 mL | |
List of Naldec substitutes (brand and generic names): | |
| Myminic | |
| Nasadec (Philippines) | |
| Nasadec 12.5 mg/5 mL x 60 mL (Medlink) | $ 1.91 |
| Nasadec 6.25 mg/1 mL x 15 mL (Medlink) | $ 1.89 |
| Nasadec oral drops 6.25 mg/mL 15 mL x 1's (Medlink) | |
| Nasadec syr 12.5 mg/5 mL 60 mL x 1's (Medlink) | |
| Nasaphen (Philippines) | |
| Nasathera (Philippines) | |
| Nasathera 325 mg/25 mg x 100's (Morishita-Seggs) | $ 8.53 |
| Nasathera 250 mg/12.5 mg x 60 mL (Morishita-Seggs) | $ 1.19 |
| Nasathera P (Philippines) | |
| Nasathera P 12.5 mg/5 mL x 60 mL (Morishita) | $ 1.17 |
| Nasathera P 6.25 mg/1 mL x 15 mL (Morishita) | $ 1.54 |
| Neo-Coldan (Philippines) | |
| Neo-Coldan 6.25 mg/1 mL x 15 mL (Ad-drugstel) | $ 1.40 |
| Nicip Cold Tablet | |
| Nicip Cold Tablet (Cipla Limited) | $ 0.04 |
| Nolex | |
| Nor Adrenalin (Japan) | |
| Nozin SR | |
| Nozin SR 50+8 Capsule (Intra Labs India Pvt Ltd) | $ 0.04 |
| Nozril Tablet | |
| Nozril Tablet (Anvi Pharmaceuticals) | $ 0.04 |
| Nozy P | |
| Nozy P 500+25+2.5 Tablet (Ind-Swift Limited) | $ 0.02 |
| Nutuss | |
| Nutuss 60 ml Syrup (Dr Alson Laboratories Pvt Ltd) | $ 0.02 |
| Nutuss 100 ml Syrup (Dr Alson Laboratories Pvt Ltd) | $ 0.02 |
| Oncet-CF (India) | |
| Oncet-CF Citrizine diHCl 5mg, Phenylpropanolamine HCl 25mg, Paracetamol 500mg TAB / 10 (Medley (Nutrakare)) | $ 0.27 |
| ONCET-CF tab 10's (Medley (Nutrakare)) | $ 0.40 |
| Oncet-CF Syrup (Medley (Nutrakare)) | $ 0.55 |
| Oncet-CF Tablet (Medley (Nutrakare)) | $ 0.05 |
| Oncet-CF SYR | |
| Oncet-CF SYR Citrizine 2.5mg, Phenylpropanolamine 12.5mg, Paracetamol 125mg, Simethicone25mg/5mL SYR / 60ml | $ 0.35 |
| Pace | |
| Pace Citrizine 5mg, Phenylpropanolamine 25mg, Paracetamol 500mg TAB / 10 | $ 0.18 |
| PACE 100MG TABLET 1 strip / 10 tablets each (Commonwealth Pharmaceuticals) | $ 0.75 |
| Pace 100mg Tablet (Commonwealth Pharmaceuticals) | $ 0.07 |
| Pararhinol (Egypt) | |
| Partuss | |
| Pediatapp (Philippines) | |
| Pediatapp 60 mL | |
| Pediatapp 15 mL | |
| Phenoxine (United States) | |
| Phenyldrine | |
| Phenylpropanolamine (Australia, Austria, Finland, France, Germany, Israel, Italy, Luxembourg, Netherlands, Poland, Switzerland, United Kingdom) | |
| Naldecon Senior EX 200 mg/5ml Syrup 118ml Bottle | $ 15.99 |
| Entex ER 10-300 mg 12 Hour Capsule | $ 1.14 |
| Codimal la capsule | $ 0.70 |
| Despec-dm tablet | $ 0.61 |
| Despec-tab tablet | $ 0.47 |
| Triaminic allergy thin strip | $ 0.35 |
| Triaminic cold-stuff nose strip | $ 0.35 |
| Conex tablet | $ 0.33 |
| Triaminic cgh-runny nose strip | $ 0.30 |
See 337 substitutes for Naldec | |
Reviews
The results of a survey conducted on ndrugs.com for Naldec are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Naldec. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
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There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
