What is Qvarspray?
Beclomethasone is a steroid. It prevents the release of substances in the body that cause inflammation.
Beclomethasone nasal is used to treat nasal symptoms such as congestion, sneezing, and runny nose caused by seasonal or year-round allergies. The Qvarspray brand of this medication is also used to keep nasal polyps from coming back after surgery to remove them.
Beclomethasone may also be used for purposes not listed in this medication guide.
Qvarspray indications
Maintenance treatment of asthma as prophylactic therapy in adults and children (≥5 years). For asthma patients who require systemic corticosteroid administration where adding Qvarspray dipropionate may reduce or eliminate the need for the systemic corticosteroids.
Qvarspray dipropionate is not indicated for the relief of acute bronchospasm.
Uses of Qvarspray in details
Qvarspray is used to treat runny nose, swelling and itching of the nose due to allergy (allergic rhinitis), hay fever and ulcerative colitis. Qvarspray reduces inflammation, swelling and irritation in nose and helps to relieve itching, sneezing and blocked or runny nose. It is also used in asthma and ulcerative colitis.
Qvarspray description
The dose which the patient gets through the mouthpiece of the device is 180 mcg.
Qvarspray contains 200 doses of finely powdered beclomethasone dipropionate mixed in a small quantity of lactose. The amount of drug received by the patient (180 mcg/dose) corresponds to that from 2 puffs of the freon-based beclomethasone inhalation aerosol with a metered dose of 100 mcg/dose. The dose to be inhaled is released from the container by pressing the device between the thumb and the forefinger. This is followed by inhalation through the device. As a result, beclomethasone dipropionate particles are transferred to their target, the lungs. Use of the Qvarspray does not require coordination of actuation of the dose and inhalation.
Qvarspray dosage
Management of Chronic Asthma: Adults and Children >12 years: 100-400 mcg twice daily. Maximum: 1000 mcg twice daily.
Children (5-12 years): 100-200 mcg twice daily. Maximum: 200-400 mcg twice daily.
Prophylaxis of Asthma: Adults and Children >12 years: 50-200 mcg twice daily. Increase if necessary to maximum 400 mcg twice daily.
Children (5-12 years): The usual starting dose is 100 mcg twice daily. Depending on the severity of asthma, the daily dose may be increased up to 400 mcg administered in 2-4 divided doses.
When patient's symptoms remain under satisfactory control, the dose should be titrated to the lowest dose at which effective control of asthma is maintained.
Therapy in New Patients: Mild Asthma: 50-100 mcg twice daily.
Moderate Asthma: 100-200 mcg twice daily.
Severe Asthma: 200-400 mcg twice daily.
When switching a patient with well-controlled asthma from another corticosteroid inhaler, initially Qvarspray 100 mcg puff should be prescribed for Qvarspray dipropionate (CFC) or budesonide 200-250 mcg; fluticasone propionate 100 mcg.
When switching a patient with poorly-controlled asthma from another corticosteroid inhaler, initially Qvarspray 100 mcg puff should be prescribed for Qvarspray dipropionate (CFC) or budesonide or fluticasone propionate 100 mcg. The dose of Qvarspray should be adjusted to response.
Use in the elderly or patients with hepatic or renal impairment: There are no special dosage recommendations for use in the elderly or in patients with hepatic or renal impairment.
Qvarspray interactions
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What other drugs will affect Qvarspray?
Due to the very low plasma concentration achieved after inhaled dosing, clinically significant drug interactions are in general unlikely. Care should be taken when co-administering with known strong CYP3A4 inhibitors (eg, ketoconazole, itraconazole, nelfinavir, ritonavir) as there is a potential for increased systemic exposure to Qvarspray.
Qvarspray side effects
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What are the possible side effects of Qvarspray?
The most commonly noted side effects associated with inhaled beclomethasone are mild cough or wheezing due to chemical irritation; these effects may be minimized by using an inhaled bronchodilator (e.g., albuterol or Ventolin) prior to the beclomethasone.
Oral candidiasis or thrush, a fungal infection of the mouth and throat, can occur in between 1 in 20 and 1 in 8 persons who use beclomethasone. The risk of thrush is greater with higher doses, but the risk in children is lower than in adults. Hoarseness may occur in as few as 1 in 20 or as many as 1 in 2 persons and is due to chemical irritation. A spacer device that can be attached to the inhaler and washing out the mouth with water following each use of beclomethasone reduces the amount of beclomethasone in the mouth and throat and reduces the risk of thrush and hoarseness.
Higher doses of inhaled beclomethasone (more than 1000 mcg/day) may result in more absorption into the body. This may decrease bone formation and increase bone breakdown (resorption), resulting in weak bones and a risk of fractures. Even higher doses (more than 1500 mcg/day in adults and 400 mcg/day in children) may suppress the adrenal glands and impair their ability to make natural glucocorticoid. People with such suppression (which can be identified by testing) need increased amounts of glucocorticoid orally or by the intravenous route during periods of high physical stress since higher amounts of glucocorticoids are needed by the body to fight physical stress. Patients receiving beclomethasone may develop easy bruising if enough beclomethasone is absorbed into the body from the lungs.
Qvarspray contraindications
Hypersensitivity to Qvarspray diproprionate or to any of the excipients of Qvarspray.
Active ingredient matches for Qvarspray:
Beclometasone in France.
| Unit description / dosage (Manufacturer) | Price, USD |
| Solution; Inhalation; Beclomethasone Dipropionate 100 mcg / dose | |
List of Qvarspray substitutes (brand and generic names): | |
| Qvar Autohaler (Greece, Luxembourg) | |
| Aerosol, Metered-Dose; Inhalation; Beclomethasone Dipropionate 50 mcg / dose | |
| ratio-Beclometasone (Canada) | |
| Recto (Argentina) | |
| Recto Menaderm (Costa Rica, Dominican Republic, El Salvador, Guatemala, Honduras, Nicaragua, Panama, Spain) | |
| Recto Menaderm NF (Argentina, Costa Rica, Dominican Republic, El Salvador, Guatemala, Honduras, Nicaragua, Panama, Spain) | |
| Respocort (Greece) | |
| Restoderm (India) | |
| Restoderm Clotrimazole 1 % w/w, Beclometasone dipropionate0.025 %, Gentamicin 0.1 % w/w, Tolnaftate 1 % w/w. CRM / 7g (Fem Care) | $ 0.35 |
| 7g (Fem Care) | $ 0.35 |
| RESTODERM 0.025%/0.1%/1% CREAM 1 tube / 7 GM cream each (Fem Care) | $ 0.34 |
| RESTODERM cream 7g (Fem Care) | $ 0.35 |
| Restoderm 0.025%/1%/1% Cream (Fem Care) | $ 0.34 |
| Rhinivict (Germany) | |
| Suspension, Metered-Dose; Nasal; Beclomethasone Dipropionate 200 doses (Dermapharm) | |
| Rhinivict 0,05mg (Germany) | |
| Rhinivict 0,1mg (Germany) | |
| Rhinomaxil (France) | |
| Suspension; Nasal; Beclomethasone Dipropionate 100 mcg / dose | |
| Riferina (Mexico) | |
| Rino-Clenil (Cyprus, Egypt, Jordan, Kuwait, Lebanon, Oman, Saudi Arabia, Sri Lanka, Syria) | |
| Rinobek (Turkey) | |
| Rinoclenil (France, Malta, Romania, Tunisia, Turkey, Venezuela) | |
| Rinosol (Argentina, Greece, Malta) | |
| Rivanase AQ (Canada) | |
| Rivanase AQ. (Canada) | |
| Salcoat (Japan, Taiwan) | |
| Salcoat 50 mcg x 100's (Teijin) | |
| Sanasthmax (Germany) | |
| Solution; Inhalation; Beclomethasone Dipropionate (Chiesi) | |
| Sanasthmax 250 Mikrogramm (Germany) | |
| Sanasthmax 400 Mikrogramm (Germany) | |
| Sanasthmax Junior (Germany) | |
| Sanasthmax Junior 50 Mikrogramm (Germany) | |
| Sanasthmyl Rotadisk (Germany) | |
| Powder; Inhalation; Beclomethasone Dipropionate 200 mcg / dose | |
| Sandoz Beclomethasone (South Africa) | |
| Selsyd-BN (India) | |
| Selsyd-BN Clotrimazole 1 % w/w, beclomethasone dipropionate0.025 % w/w, neomycin 0.5 %w/w. CRM / 15g (Psycorem) | $ 0.66 |
| SELSYD-BN cream 15g (Psycorem) | $ 0.66 |
| Sertacide-B (India) | |
| Sertacide-B Sertaconazole 2 %, beclometasone 0.025 %. CRM / 10g (Cipla (Xterna)) | $ 1.08 |
| SERTACIDE-B cream 10g (Cipla (Xterna)) | $ 1.08 |
| Shelic Cream (India) | |
| Shelic Cream Beclometasone 0.025 %, Salicylic acid 3 %. CRM / 15g (Zee Lab) | $ 0.70 |
| 15g (Zee Lab) | $ 0.70 |
| SHELIC CREAM cream 15g (Zee Lab) | $ 0.70 |
| Siloderm Mixi (India) | |
| Siloderm Mixi Clotrimazole 1 % w/w, Beclometasone dipropionate0.025 % w/w, Gentamicinsulfate 1 % w/w. CRM / 10g (US Vitamins Limited) | $ 0.25 |
| 10g (US Vitamins Limited) | $ 0.25 |
| Siloderm Mixi Skin 10 gm Cream (US Vitamins Limited) | $ 0.49 |
| SILODERM MIXI CREAM 1 tube / 10 GM cream each (US Vitamins Limited) | $ 0.59 |
| SILODERM MIXI cream 10g (US Vitamins Limited) | $ 0.49 |
See 899 substitutes for Qvarspray | |
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Information checked by Dr. Sachin Kumar, MD Pharmacology
