Silyhep indications
Pernicious anemia, both uncomplicated and accompanied by nervous system involvement.
Dietary deficiency of Vitamin B12, occurring in strict vegetarians and in their breast-fed infants. (Isolated vitamin B12 deficiency is very rare).
Malabsorption of vitamin B12, resulting from structural or functional damage to the stomach, where intrinsic factor is secreted or to the ileum, where intrinsic factor facilitates vitamin B12 absorption. These conditions include tropical sprue, and nontropical sprue (idiopathic steatorrhea, gluten-induced enteropathy). Folate deficiency in these patients is usually more severe than vitamin B12 deficiency.
Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (ingestion of corrosives, extensive neoplasia), and a number of conditions associated with a variable degree of gastric atrophy (such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy). Total gastrectomy always produces vitamin B12 deficiency.
Structural lesions leading to vitamin B12 deficiency include regional ileitis, ileal resections, malignancies, etc.
Competition for Vitamin B12 by intestinal parasites or bacteria.
The fish tapeworm (Diphyilobothrium latum) absorbs huge quantities of vitamin B12 and infested patients often have associated gastric atrophy. The blind-loop syndrome may produce deficiency of Vitamin B12 or folate.
Inadequate utilization of vitamin B12. This may occur if antimetabolites for the vitamin are employed in the treatment of neoplasia.
For the Schilling Test.
Uses of Silyhep in details
Silyhep is a liver protectant and antioxidant. Treatment with Silyhep has shown slightly improved liver function, and showed improvement in patients with type 2 diabetes and diabetic nephropathy (kidney disease).
Silyhep description
Each 70-mg capsule contains Silyhep 70 mg (calculated as Silyhep) in dried extract of milk thistle fruits 86.5-93.3 mg while the 140-mg capsule contains Silyhep 140 mg (calculated as Silyhep) in dried extract of milk thistle fruits 173-186.6 mg.
Silyhep dosage
Unless otherwise directed by the physician: Adults and Children >12 years: Usual Dose: Initially, 1 cap 3 times daily.
Maintenance Dose: 1 cap 2 times daily.
Administration: Silyhep should be taken whole with some liquid before meals.
The physician should decide on the length of treatment.
Silyhep interactions
Fish lipid oil prevents blood clotting too quickly, therefore patients who are treated with anticoagulants must consult their doctor before taking Silyhep.
Silyhep side effects
Body as a Whole: Enlarged abdomen, asthenia, body odor, chest pain, chills, suicide, fever, generalized edema, fungal infection, malaise, neck pain, neoplasm, rheumatoid arthritis, and sudden death.
Cardiovascular System: Arrhythmia, bypass surgery, cardiac arrest, hyperlipemia, hypertension, migraine, myocardial infarct, myocardial ischemia, occlusion, peripheral vascular disorder, syncope, and tachycardia.
Digestive System: Anorexia, constipation, dry mouth, dysphagia, colitis, fecal incontinence, gastritis, gastroenteritis, gastrointestinal disorder, increased appetite, intestinal obstruction, melena, pancreatitis, tenesmus, and vomiting.
Hematologic-Lymphatic System: Lymphadenopathy.
Infections and Infestations: Viral infection.
Metabolic and Nutritional Disorders: Edema, hyperglycemia, increased ALT, and increased AST.
Musculoskeletal System: Arthralgia, arthritis, myalgia, pathological fracture, and tendon disorder.
Nervous System: Central nervous system neoplasia, depression, dizziness, emotional lability, facial paralysis, insomnia, vasodilatation, and vertigo.
Respiratory System: Asthma, bronchitis, increased cough, dyspnea, epistaxis, laryngitis, pharyngitis, pneumonia, rhinitis, and sinusitis.
Skin: Alopecia, eczema, pruritus, and sweating.
Special Senses: Cataract.
Urogenital System: Cervix disorder, endometrial carcinoma, epididymitis, and impotence.
Silyhep contraindications
Hypersensitivity to milk thistle fruits and/or other plants of the compositae, or to any of the excipients of Silyhep.
Active ingredient matches for Silyhep:
Silibinin in Taiwan.
| Unit description / dosage (Manufacturer) | Price, USD |
| Silyhep / Kojar 150 mg | |
| Silyhep / Souriree 5 x 6's | |
| Silyhep / Souriree 30 x 6's | |
| Silyhep 150 mg x 10 Blister x 10 Tablet | |
List of Silyhep substitutes (brand and generic names): | |
| Silygen-H (Taiwan) | |
| Silygen-H 150 mg x 1000's | |
| Silyma (Taiwan) | |
| Silyma 150 mg | |
| Silyman (South Korea) | |
| Silymarin (Bosnia & Herzegowina, Hong Kong, Oman, Taiwan) | |
| Capsule; Oral; Milk Thistle 70 mg (Sedico impex) | |
| Capsule; Oral; Milk Thistle 140 mg (Sedico impex) | |
| Capsule; Oral; Milk Thistle 200 mg (Sedico impex) | |
| Capsule; Oral; Milk Thistle 110 mg (Sedico impex) | |
| Silymarin / Tai Yu 70 mg (Sedico impex) | |
| Silymarin 70 mg x 30's (Sedico impex) | |
| Silymarin 70 mg x 1, 000's (Sedico impex) | |
| Silymarin / S.C. 35 mg (Sedico impex) | |
| Silymarin / S.C. 150 mg (Sedico impex) | |
| Silymarin / Biome 150 mg (Sedico impex) | |
| Silymarin / P.L. 70 mg x 1000's (Sedico impex) | |
| Silymarin AL (Czech Republic, Germany) | |
| Silymarin Belupo (Croatia (Hrvatska)) | |
| Silymarin dura (Germany) | |
| Silymarin Forte (Bosnia & Herzegowina) | |
| Silymarin Forte Belupo (Bosnia & Herzegowina) | |
| Silymarin Instant (Romania) | |
| Silymarin Sedico (Egypt) | |
| Silymarin Siromed (Lithuania) | |
| Silymarin Stada (Germany) | |
| Silymarin Vramed (Bulgaria) | |
| Silymarin-CT (Germany) | |
| Silymarin-Hexal (Luxembourg) | |
| Silyme-V (Taiwan) | |
| Silyme-V 70 mg | |
| Silymin (Taiwan) | |
| Silymin 150 mg | |
| Silyrin (India) | |
| Silyrin 35mg/5mL SUSP / 100ml (Talent Laboratories) | $ 0.72 |
| Silyrin -140 3 Blister x 10 Tablet (Talent Laboratories) | |
| Silyrin -70 3 Blister x 10 Tablet (Talent Laboratories) | |
| Silyrin 100 ml Suspension (Talent Laboratories) | $ 0.04 |
| Silyrin 140 mg Tablet (Talent Laboratories) | $ 0.07 |
| Silyrin 70 mg Tablet (Talent Laboratories) | $ 0.04 |
| Simepar Forte (Estonia, Latvia) | |
| Sison (India) | |
| Sison 70mg CAP / 10 (Dr Alson Laboratories Pvt Ltd) | $ 0.51 |
| Sison 140mg CAP / 10 (Dr Alson Laboratories Pvt Ltd) | $ 0.90 |
| 70 mg x 10's (Dr Alson Laboratories Pvt Ltd) | $ 0.51 |
| 140 mg x 10's (Dr Alson Laboratories Pvt Ltd) | $ 0.90 |
| Sison 140 mg Capsule (Dr Alson Laboratories Pvt Ltd) | $ 0.09 |
| Sison 70 mg Capsule (Dr Alson Laboratories Pvt Ltd) | $ 0.05 |
| SISON cap 70 mg x 10's (Dr Alson Laboratories Pvt Ltd) | $ 0.51 |
See 444 substitutes for Silyhep | |
References
- PubChem. "silibinin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "Silibinin A". http://www.drugbank.ca/drugs/DB09298 (accessed September 17, 2018).
- DTP/NCI. "NSC651520: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Silyhep are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Silyhep. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
1 consumer reported useful
Was the Silyhep drug useful in terms of decreasing the symptom or the disease?According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
| Users | % | ||
|---|---|---|---|
| Useful | 1 | 100.0% | |
Consumer reported price estimates
No survey data has been collected yet1 consumer reported time for results
To what extent do I have to use Silyhep before I begin to see changes in my health conditions?As part of the reports released by ndrugs.com website users, it takes 2 days and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Silyhep. To get the time effectiveness of using Silyhep drug by other patients, please click here.
| Users | % | ||
|---|---|---|---|
| 2 days | 1 | 100.0% | |
1 consumer reported age
| Users | % | ||
|---|---|---|---|
| 46-60 | 1 | 100.0% | |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
