Spazgan Uses

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Spazgan indications

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Oral

As an antispasmodic

Adult: 40-80 mg tid.

Child: 1-6 yr: 20 mg 3-4 times daily; >6 yr: 40 mg tid.

Uses of Spazgan in details

Spazgan is used to relieve spasm of smooth muscles in organs such as stomach and heart. It is used in the treatment of pain due to some condition such as ulcers of the intestine, irritable bowel syndrome, various diseases of intestines, pain due to gall stones and stones in the kidneys, pain due to various diseases of the liver and gall bladder, Spazgan is also to treat certain types of headaches, for painful periods, and to relieve cervical spasm during labor.

Spazgan description

Spazgan (INN, also known as drotaverin) is an antispasmodic drug, structurally related to papaverine. Spazgan is a selective inhibitor of phosphodiesterase 4, and has no anticholinergic effects. Spazgan has been shown to possess dose-dependant analgesic effects in animal models. One small study has shown Spazgan to be eliminated mainly non-renally.

Spazgan dosage

Oral

As an antispasmodic

Adult: 40-80 mg tid.

Child: 1-6 yr: 20 mg 3-4 times daily; >6 yr: 40 mg tid.

Spazgan interactions

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Spazgan is compatible with other drugs.

Spazgan side effects

The spasmolytic effect of Spazgan hydrochloride develops within minutes without appreciable side effects. It causes no pathological alterations in the tissues of higher animals. No irritable effect on tissue. Embryotoxicity or teratogenic effects were not found.

Spazgan contraindications

Contraindications

Severe renal/hepatic/cardiac dysfunction. Porphyria.

Active ingredient matches for Spazgan:

Drotaverine in Latvia.


List of Spazgan substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
SPASNA 80MG TABLET 1 strip / 10 tablets each (Albert David Ltd)$ 0.53
Spasna 80mg Tablet (Albert David Ltd)$ 0.05
Injectable; Injection; Drotaverine Hydrochloride 20 mg / ml (Shreya)
Tablet; Oral; Drotaverine Hydrochloride 40 mg (Shreya)
Tablet; Oral; Drotaverine Hydrochloride 80 mg (Shreya)
Spazwin Mefenamic acid 250 mg, drotaverine hydrochloride 80mg, activated dimeticone 20mg, papain 40 mg, lactobacillus 90 millioncells. FC-TAB / 10 (Waves-Biotech)
SPAZWIN film-coated tab 10's (Waves-Biotech)
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Talo DS 80 mg Tablet (Diamond Drugs Pvt Ltd)$ 0.04
TALO DS 80MG TABLET 1 strip / 10 tablets each (Diamond Drugs Pvt Ltd)$ 0.41
Talo DS 80mg Tablet (Diamond Drugs Pvt Ltd)$ 0.04
TAME 40MG INJECTION 1 vial / 2 ML injection each (Elan Pharma India Pvt Ltd)$ 0.17
40 mg x 1's (HOS & INS)$ 0.16
Tav 40 mg Injection (HOS & INS)$ 0.08
Tav 40mg INJ / 1 (HOS & INS)$ 0.16
TAV inj 40 mg x 1ml (HOS & INS)$ 0.16
Tav 40mg INJ / 1 (HOS & INS)$ 0.16
Tavam 40 mg Injection (Amrit Remedies Pvt. Ltd. (Health Biotech Pvt Ltd.))$ 0.09
Toverine 40 mg x 1, 000's (T. O. Chemicals)
Toverine tab 40 mg 1000's (T. O. Chemicals)
TROSPA Capsule/ Tablet / 80mg / 10 units (Dr Reddy Laboratories Ltd)$ 0.48
TROSPA Capsule/ Tablet / 40mg / 10 units (Dr Reddy Laboratories Ltd)$ 0.29
Trospa 40mg TAB / 10 (Dr Reddy Laboratories Ltd)$ 0.28
Trospa 80mg TAB / 10 (Dr Reddy Laboratories Ltd)$ 0.42
Trospa 80 mg Tablet (Dr Reddy Laboratories Ltd)$ 0.04
Trospa 40 mg Tablet (Dr Reddy Laboratories Ltd)$ 0.03
TROSPA 80 MG TABLET 1 strip / 10 tablets each (Dr Reddy Laboratories Ltd)$ 0.51
TROSPA tab 40 mg x 10's (Dr Reddy Laboratories Ltd)$ 0.32
TROSPA tab 80 mg x 10's (Dr Reddy Laboratories Ltd)$ 0.53
Trospa 40mg TAB / 10 (Dr Reddy Laboratories Ltd)$ 0.28
Trospa 80mg TAB / 10 (Dr Reddy Laboratories Ltd)$ 0.42
UVERINE tab 80 mg x 10's (Unikind)$ 0.54
UVERINE inj 80 mg x 2ml (Unikind)$ 0.05
Tablet; Oral; Drotaverine Hydrochloride 40 mg
Xitaverin 80 mg Tablet (Xieon Lifesciences Pvt. Ltd.)$ 0.05

References

  1. PubChem. "drotaverine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "drotaverine". http://www.drugbank.ca/drugs/DB06751 (accessed September 17, 2018).
  3. MeSH. "Vasodilator Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Spazgan are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Spazgan. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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