Tav Uses

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Tav indications

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Oral

As an antispasmodic

Adult: 40-80 mg tid.

Child: 1-6 yr: 20 mg 3-4 times daily; >6 yr: 40 mg tid.

Uses of Tav in details

Tav is used to relieve spasm of smooth muscles in organs such as stomach and heart. It is used in the treatment of pain due to some condition such as ulcers of the intestine, irritable bowel syndrome, various diseases of intestines, pain due to gall stones and stones in the kidneys, pain due to various diseases of the liver and gall bladder, Tav is also to treat certain types of headaches, for painful periods, and to relieve cervical spasm during labor.

Tav description

Tav (INN, also known as drotaverin) is an antispasmodic drug, structurally related to papaverine. Tav is a selective inhibitor of phosphodiesterase 4, and has no anticholinergic effects. Tav has been shown to possess dose-dependant analgesic effects in animal models. One small study has shown Tav to be eliminated mainly non-renally.

Tav dosage

Oral

As an antispasmodic

Adult: 40-80 mg tid.

Child: 1-6 yr: 20 mg 3-4 times daily; >6 yr: 40 mg tid.

Tav interactions

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Tav is compatible with other drugs.

Tav side effects

The spasmolytic effect of Tav hydrochloride develops within minutes without appreciable side effects. It causes no pathological alterations in the tissues of higher animals. No irritable effect on tissue. Embryotoxicity or teratogenic effects were not found.

Tav contraindications

Contraindications

Severe renal/hepatic/cardiac dysfunction. Porphyria.

Active ingredient matches for Tav:

Drotaverine in India.


Unit description / dosage (Manufacturer)Price, USD
40 mg x 1's$ 0.16
Tav 40 mg Injection$ 0.08
Tav 40mg INJ / 1$ 0.16
TAV inj 40 mg x 1ml (Hos & Ins)$ 0.16
Tav 40mg INJ / 1$ 0.16

List of Tav substitutes (brand and generic names):

Spasmoter 40mg Injection (Zuvista (Zuventus Health Care Ltd.))$ 0.08
Spasmoter 80mg Tablet (Zuvista (Zuventus Health Care Ltd.))$ 0.04
Spasmoter Inj 40 mg Injection (Zuvista (Zuventus Health Care Ltd.))$ 0.08
SPASNA 40MG TABLET 1 strip / 10 tablets each (Albert David Ltd)$ 1.50
SPASNA 80MG TABLET 1 strip / 10 tablets each (Albert David Ltd)$ 0.53
Spasna 80mg Tablet (Albert David Ltd)$ 0.05
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Injectable; Injection; Drotaverine Hydrochloride 20 mg / ml (Shreya)
Tablet; Oral; Drotaverine Hydrochloride 40 mg (Shreya)
Tablet; Oral; Drotaverine Hydrochloride 80 mg (Shreya)
Spazwin Mefenamic acid 250 mg, drotaverine hydrochloride 80mg, activated dimeticone 20mg, papain 40 mg, lactobacillus 90 millioncells. FC-TAB / 10 (Waves-Biotech)
SPAZWIN film-coated tab 10's (Waves-Biotech)
Talo DS 80 mg Tablet (Diamond Drugs Pvt Ltd)$ 0.04
TALO DS 80MG TABLET 1 strip / 10 tablets each (Diamond Drugs Pvt Ltd)$ 0.41
Talo DS 80mg Tablet (Diamond Drugs Pvt Ltd)$ 0.04
TAME 40MG INJECTION 1 vial / 2 ML injection each (Elan Pharma India Pvt Ltd)$ 0.17
Tavam 40 mg Injection (Amrit Remedies Pvt. Ltd. (Health Biotech Pvt Ltd.))$ 0.09
Toverine 40 mg x 1, 000's (T. O. Chemicals)
Toverine tab 40 mg 1000's (T. O. Chemicals)
TROSPA Capsule/ Tablet / 80mg / 10 units (Dr Reddy Laboratories Ltd)$ 0.48
TROSPA Capsule/ Tablet / 40mg / 10 units (Dr Reddy Laboratories Ltd)$ 0.29
Trospa 40mg TAB / 10 (Dr Reddy Laboratories Ltd)$ 0.28
Trospa 80mg TAB / 10 (Dr Reddy Laboratories Ltd)$ 0.42
Trospa 80 mg Tablet (Dr Reddy Laboratories Ltd)$ 0.04
Trospa 40 mg Tablet (Dr Reddy Laboratories Ltd)$ 0.03
TROSPA 80 MG TABLET 1 strip / 10 tablets each (Dr Reddy Laboratories Ltd)$ 0.51
TROSPA tab 40 mg x 10's (Dr Reddy Laboratories Ltd)$ 0.32
TROSPA tab 80 mg x 10's (Dr Reddy Laboratories Ltd)$ 0.53
Trospa 40mg TAB / 10 (Dr Reddy Laboratories Ltd)$ 0.28
Trospa 80mg TAB / 10 (Dr Reddy Laboratories Ltd)$ 0.42
UVERINE tab 80 mg x 10's (Unikind)$ 0.54
UVERINE inj 80 mg x 2ml (Unikind)$ 0.05
Tablet; Oral; Drotaverine Hydrochloride 40 mg
Xitaverin 80 mg Tablet (Xieon Lifesciences Pvt. Ltd.)$ 0.05

References

  1. PubChem. "TAV". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. PubChem. "drotaverine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "drotaverine". http://www.drugbank.ca/drugs/DB06751 (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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