What is Futaron?
Futaron is a substance that is used to treat bacterial infections. It will not work for colds, flu, or other virus infections.
Futaron is available only with your doctor's prescription.
Futaron indications
Futaron is active in vitro against Staphylococcus aureus, most coagulase-negative staphylococci, Corynebacterium species, most clostridium species. Futaron has no useful activity against enterococci or most Gram-negative bacteria (except Neisseria, Moraxella, Legionella pneumophila and Bacteroides fragilis). Futaron is active in vitro and clinically against Mycobacterium leprae but has only marginal activity against Mycobacterium tuberculosis.
One important use of Futaron clinically is its activity against methicillin-resistant Staphylococcus aureus. Many strains of MRSA remain sensitive to Futaron, but because there is a low genetic barrier to drug resistance (a single point mutation is all that is required), Futaron must never be used on its own to treat serious MRSA infection and should be combined with another antimicrobial such as rifampicin.
Futaron is often found in topical skin and eye preparations (e.g., Fucibet), a use which has been contested.
Uses of Futaron in details
Futaron is used for treating various bacterial skin infections and some infections of bone, heart, lungs and eyes.
Futaron description
Futaron is a bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Futaron A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
Futaron dosage
Cream/Ointment: Apply to the affected area 2-3 times a day, generally for a period of 7 days.
Futaron ointment can be used with or without a covering dressing.
Futaron interactions
Futaron use in patients who are receiving high doses of theophylline may be associated with an increase in serum theophylline levels and potential theophylline toxicity. In case of theophylline toxicity and/or elevated serum theophylline levels, the dose of theophylline should be reduced while the patient is receiving concomitant erythromycin therapy.
Concomitant administration of erythromycin and digoxin has been reported to result in elevated digoxin serum levels. There have been reports of increased anticoagulant effects when erythromycin and oral anticoagulants were used concomitantly. Increased anticoagulation effects due to interactions of erythromycin with various oral anticoagulents may be more pronounced in the elderly.
Concurrent use of erythromycin and ergotamine or dihydroergotamine has been associated in some patients with acute ergot toxicity characterized by severe peripheral vasospasm and dysesthesia.
Futaron has been reported to decrease the clearance of triazolam and midazolam and thus may increase the pharmacologic effect of these benzodiazepines.
The use of erythromycin in patients concurrently taking drugs metabolized by the cytochrome P450 system may be associated with elevations in serum levels of these other drugs. There have been reports of interactions of erythromycin with carbamazepine, cyclosporine, tacrolimus, hexobarbital, phenytoin, alfentanil, cisapride, disopyramide, lovastatin, bromocriptine, valproate, terfenadine, and astemizole. Serum concentrations of drugs metabolized by the cytochrome P450 system should be monitored closely in patients concurrently receiving erythromycin.
Futaron has been reported to significantly alter the metabolism of nonsedating antihistamines terfenadine and astemizole when taken concomitantly. Rare cases of serious cardiovascular adverse events, including electrocardiographic QT/QTc interval prolongation, cardiac arrest, torsades de pointes, and other ventricular arrhythmias have been observed. In addition, deaths have been reported rarely with concomitant administration of terfenadine and erythromycin.
There have been postmarketing reports of drug interactions when erythromycin is coadministered with cisapride, resulting in QT prolongation, cardiac arrythmias, ventricular tachycardia, ventricular fibrulation, and torsades de pointes, most like due to inhibition of hepatic metabolism of cisapride by erythromycin. Fatalities have been reported.
Patients receiving concomitant lovastatin and erythromycin should be carefully monitored; cases of rhabdomyolysis have been reported in seriously ill patients.
Futaron side effects
See also:
What are the possible side effects of Futaron?
Occasionally hypersensitivity reactions eg, skin rashes, weak pain and irritation may occur. If these symptoms occur, discontinue Futaron.
Futaron contraindications
Futaron is contraindicated in patients with known hypersensitivity to this antibiotic. Futaron is contraindicated in patients taking terfenadine, astemizole, or cisapride.
Topical Ery 2% Pads are contraindicated in those individuals who have shown hypersensitivity to any of its components.
Active ingredient matches for Futaron:
Fusidic Acid in Georgia.
List of Futaron substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Futaderm (Indonesia) | |
| Futaderm 20 mg x 10 g (Interbat) | $ 4.34 |
| Futasole (Oman) | |
| Futasole 2% (Egypt) | |
| Futen (Taiwan) | |
| Futen 2 % x 1 g | |
| Futen 2 % x 5 g | |
| Futen 2 % x 8 g | |
| Futen 2 % x 10 g | |
| Futen 2 % x 15 g | |
| Futen 2 % x 20 g | |
| Futen 2 % x 50 g | |
| Futhalm 1% (Egypt) | |
| FUTOP (India) | |
| FUTOP Cream/ Gel/ Ointment / 20mg per gm / 10gm units (Cosme Healthcare (CFL Pharmaceuticals Ltd)) | $ 0.72 |
| FUTOP Cream/ Gel/ Ointment / 20mg per gm / 5gm units (Cosme Healthcare (CFL Pharmaceuticals Ltd)) | $ 0.45 |
| Futop 2% w/w OINT / 5g (Cosme Healthcare (CFL Pharmaceuticals Ltd)) | $ 0.33 |
| Futop 1 boä (Cosme Healthcare (CFL Pharmaceuticals Ltd)) | |
| 2 % w/w x 5g (Cosme Healthcare (CFL Pharmaceuticals Ltd)) | $ 0.33 |
| Futop Skin 5 gm Cream Cream (Cosme Healthcare (CFL Pharmaceuticals Ltd)) | $ 0.08 |
| Futop Skin 5 gm Ointment (Cosme Healthcare (CFL Pharmaceuticals Ltd)) | $ 0.09 |
| Futop Skin 10 gm Ointment (Cosme Healthcare (CFL Pharmaceuticals Ltd)) | $ 0.08 |
| Futop Skin 10 gm Cream Cream (Cosme Healthcare (CFL Pharmaceuticals Ltd)) | $ 0.08 |
| FUTOP 2% CREAM 1 tube / 10 GM cream each (Cosme Healthcare (CFL Pharmaceuticals Ltd)) | $ 0.97 |
| FUTOP oint 20 mg x 5g (Cosme Healthcare (CFL Pharmaceuticals Ltd)) | $ 0.52 |
| Futop 2% w/w OINT / 5g (Cosme Healthcare (CFL Pharmaceuticals Ltd)) | $ 0.33 |
| Futop 2% Cream (Cosme Healthcare (CFL Pharmaceuticals Ltd)) | $ 0.97 |
| Futop Cream | |
| Futop Cream Fusidic Acid 20mg, K sorbate2.7mg CRM / 10g | $ 0.75 |
| Futop Cream Fusidic Acid 20mg, K sorbate2.7mg CRM / 5g | $ 0.42 |
| Futop Ointment | |
| Futop Ointment 20mg OINT / 10g | $ 0.72 |
| Futop Ointment 20mg OINT / 5g | $ 0.75 |
| Fuzi | |
| Fuzi Skin 10 gm Cream (Adips Laboratories Ltd.) | $ 0.08 |
| Fuzi Skin 5 gm Cream (Adips Laboratories Ltd.) | $ 0.10 |
| Fuzi 20mg Cream (Adips Laboratories Ltd.) | $ 0.88 |
| FUZI (ADIPS) | |
| FUZI / ADIPS CREAM 1 tube / 10 GM cream each (Adips Laboratories Ltd) | $ 0.88 |
| Fuzic | |
| Fuzic Skin 10 gm Cream (Canbro Healthcare) | $ 0.83 |
| Gelbiotic (Argentina) | |
| Germacid (Vietnam) | |
| Germacid 2 % x 1 tube 5 g (Raza) | |
| Germacid 2 % x 1 tube 15 g (Raza) | |
| Gzlcon F | |
| Gzlcon F Skin 10 gm Cream (Gedzrlvin Pharmaceuticals) | $ 1.20 |
| Hhfudic (India) | |
| Hhfudic Skin 10 gm Cream (H&H Pharmaceuticals Pvt Ltd) | $ 1.93 |
| HHFUDIC CREAM 1 tube / 10 GM cream each (H&H Pharmaceuticals Pvt Ltd) | $ 2.65 |
| HHFUDIC cream 10g (H&H Pharmaceuticals Pvt Ltd) | $ 2.11 |
| Hhfudic Cream (H&H Pharmaceuticals Pvt Ltd) | $ 2.78 |
| HoeFoban (Vietnam) | |
| HoeFoban 2 % x 1 tube 5 g | |
See 709 substitutes for Futaron | |
References
- PubChem. "fusidic acid". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "fusidic acid". http://www.drugbank.ca/drugs/DB02703 (accessed September 17, 2018).
- DTP/NCI. "fusidic acid: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Futaron are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Futaron. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
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Information checked by Dr. Sachin Kumar, MD Pharmacology
