Betheran Uses

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What is Betheran?

Betheran stimulates your bladder to empty.

Betheran is used to treat urinary retention (difficulty urinating), which may occur after surgery, after delivering a baby, and in other situations.

Betheran may also be used for purposes other than those listed in this medication guide.

Betheran indications

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Betheran is indicated for the treatment of acute postoperative and postpartum non obstructive (functional) urinary retention and for neurogenic atony of the urinary bladder with retention.

How should I use Betheran?

Use Betheran as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Betheran.

Uses of Betheran in details

Betheran is used to treat acute urirary retention after surgrey, childbirth and due to various diseases of the urinary bladder. Betheran may also be used for treating a disease called congenital megacolon (abnormal dilatation of large intestine which is present from birth) and gastro-esophageal reflux and reflux esophagitis (inflammation of the esophagus due to regurgitation).

Betheran description

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A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Betheran is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, cardiac rate changes, and bronchial spasms.

Betheran dosage

Dosage must be individualized, depending on the type and severity of the condition to be treated.

Preferably give the drug when the stomach is empty. If taken soon after eating, nausea and vomiting may occur.

The usual adult oral dose ranges from 10 to 50 mg three or four times a day. The minimum effective dose is determined by giving 5 to 10 mg initially and repeating the same amount at hourly intervals until satisfactory response occurs, or until a maximum of 50 mg has been given. The effects of the drug sometimes appear within 30 minutes and are usually maximal within 60 to 90 minutes. The drug effects persist for about one hour.

If necessary, the effects of the drug can be abolished promptly by atropine.

How supplied

Betheran Tablets, USP

5 mg - White, 7/16" diameter, round flat faced bevel edge tablets: one side scored and debossed BCL bisect 5, one side debossed 832, in bottles of 100 and 1000, and in unit dose cartons of 100 tablets (10 cards containing 10 tablets each).

10 mg - White, 7/16" diameter, round flat faced bevel edge tablets; one side scored and debossed BCL bisect 10, one side debossed 832, in bottles of 100. 250 and 1000, and in unit dose cartons of 100 tablets (10 cards containing 10 tablets each).

25 mg - Yellow, 7/16" diameter, round flat faced bevel edge tablets; one side scored and debossed BCL bisect 25, one side debossed 832, in bottles of 100, 250, 500 and 1000, and in unit dose cartons of 100 tablets (10 cards containing 10 tablets each).

50 mg - Yellow, 7/16" diameter, round fiat faced bevel edge tablets; one side scored and debossed BCL bisect 50, one side debossed 832, in bottles of 100, 500 and 1000. and in unit dose cartons of 100 tablets (10 cards containing 10 tablets each).

Store at 20-25°C (68-7?°F) and excursions permitted to 15-30"C (59-86°F).

Dispense in a tight container as defined in the USP

Keep out of reach of children.

Rev. 05-05. Manufactured by: UPSHER-SMITH LABORATORIES, INC. Minneapolis, MN 55447. FDA Rev date: 6/1/2005

Betheran interactions

See also:
What other drugs will affect Betheran?

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Special care is required if this drug is given to patients receiving ganglion blocking compounds because a critical fall in blood pressure may occur. Usually, severe abdominal symptoms appear before there is such a fall in the blood pressure.

Betheran side effects

See also:
What are the possible side effects of Betheran?

Adverse reactions are rare following oral administration of Betheran, but are more common following subcutaneous injection. Adverse reactions are more likely to occur when dosage is increased.

The following adverse reactions have been observed: Body as a Whole: malaise; Digestive: abdominal cramps or discomfort, colicky pain, nausea and belching, diarrhea, borborygmi, salivation; Renal: urinary urgency; Nervous System: headache; Cardiovascular: a fall in blood pressure with reflex tachycardia, vasomotor response; Skin: flushing producing a feeling of warmth, sensation of heat about the face, sweating; Respiratory: bronchial constriction, asthmatic attacks; Special Senses: lacrimation, miosis,

Causal Relationship Unknown

The following adverse reactions have been reported, and a causal relationship to therapy with Betheran has not been established: Body as a Whole: malaise; Nervous System: seizures.

Betheran contraindications

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What is the most important information I should know about Betheran?

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Hypersensitivity to Betheran tablets, hyperthyroidism, peptic ulcer, latent or active bronchial asthma, pronounced bradycardia or hypotension, vasomotor Instability, coronary artery disease, epilepsy and parkinsonism.

Betheran should not be employed when the strength or integrity of the gastrointestinal or bladder wall is in question, or in the presence of mechanical obstruction; when increased muscular activity of the gastrointestinal tract or urinary bladder might prove harmful, as following recent urinary bladder surgery, gastrointestinal resection and anastomosis, or when there Is possible gastrointestinal obstruction; in bladder neck obstruction, spastic gastrointestinal disturbances, acute inflammatory lesions of the gastrointestinal tract, or peritonitis; or in marked vagotonia.

Active ingredient matches for Betheran:

Bethanechol chloride in India.

Bethanechol


Unit description / dosage (Manufacturer)Price, USD
25 mg x 10's$ 1.57
Betheran 25 mg Tablet$ 0.16
Betheran 25mg TAB / 10$ 1.57
BETHERAN 25 MG TABLET 1 strip / 10 tablets each (Ranbaxy Laboratories Ltd)$ 1.57
BETHERAN tab 25 mg x 10's (Ranbaxy)$ 1.57
Betheran 25mg TAB / 10$ 1.57

List of Betheran substitutes (brand and generic names):

Dampurine 25 mg x 1000's
Tablet; Oral; Bethanechol Chloride 10 mg (Roberts)
Tablet; Oral; Bethanechol Chloride 25 mg (Roberts)
Tablet; Oral; Bethanechol Chloride 50 mg (Roberts)
Macpee 25mg TAB / 10 (Intas)$ 1.29
MACPEE 10 MG TABLET 1 strip / 10 tablets each (Intas)$ 1.63
MACPEE 25 MG TABLET 1 strip / 10 tablets each (Intas)$ 1.78
MACPEE tab 25 mg x 10's (Intas)$ 1.29
Macpee 10mg Tablet (Intas)$ 0.16
Macpee 25mg Tablet (Intas)$ 0.18
Tablet; Oral; Bethanechol Chloride 10 mg (Glenwood)
Tablet; Oral; Bethanechol Chloride 25 mg (Glenwood)
Tablet; Oral; Bethanechol Chloride 10 mg (Glenwood)
Tablet; Oral; Bethanechol Chloride 25 mg (Glenwood)
Tablet; Oral; Bethanechol Chloride 5 mg (Glenwood)
Tablet; Oral; Bethanechol Chloride 10 mg (Glenwood)
Tablet; Oral; Bethanechol Chloride 25 mg (Glenwood)
Tablet; Oral; Bethanechol Chloride 10 mg
Tablet; Oral; Bethanechol Chloride 25 mg
Tablet; Oral; Bethanechol Chloride 50 mg
PHL-bethanechol Chloride tablet 10 mg (Pharmel Inc (Canada))
PHL-bethanechol Chloride tablet 25 mg (Pharmel Inc (Canada))
PHL-bethanechol Chloride tablet 50 mg (Pharmel Inc (Canada))
Tablet; Oral; Bethanechol Chloride 10 mg
Tablet; Oral; Bethanechol Chloride 25 mg

References

  1. PubChem. "bethanechol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "bethanechol". http://www.drugbank.ca/drugs/DB01019 (accessed September 17, 2018).
  3. MeSH. "Parasympathomimetics". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Betheran are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Betheran. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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