Femkof indications
Femkof Injection, USP, after dilution in isotonic sodium chloride injection, may be indicated in the treatment of patients with (1) hypochloremic states and (2) metabolic alkalosis.
Uses of Femkof in details
Femkof is used for the relief of cough in the form of cough expectorant. It is also used as an injection to treat patients with hypochloremia and metabolic alkalosis.
Femkof dosage
Femkof Injection, USP is administered intravenously and must be diluted before use. Solutions for intravenous infusion should not exceed a concentration of 1% to 2% of Femkof.
Dosage is dependent upon the condition and tolerance of the patient. It is recommended that the contents of one to two vials (100 to 200 mEq) be added to 500 or 1000 mL of isotonic (0.9%) sodium chloride injection. The rate of intravenous infusion should not exceed 5 mL per minute in adults (approximately 3 hours for infusion of 1000 mL). Dosage should be monitored by repeated serum bicarbonate determinations.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. See PRECAUTIONS.
Femkof interactions
In a treatment, patients should be monitored closely for signs of ammonia poisoning: pallor, sweating, irregular breathing, vomiting, bradycardia, arrhythmias, tremors, convulsions and coma.
Femkof should be used with caution in patients with heart and lung failure.
A longer-term correction of a hypochloraemia in patients with secondary metabolic alkalosis due to an intracellular potassium depletion can not be achieved by the sole administration of Femkof. Concomitant administration of potassium is also necessary.
Femkof side effects
See also:
What are the possible side effects of Femkof?
Rapid intravenous administration of Femkof may be accompanied by pain or irritation at the site of injection or along the venous route.
Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia (from large volume diluent).
If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures and save the remainder of the fluid for examination if deemed necessary.
Femkof contraindications
Femkof is contraindicated in patients with severe impairment of renal or hepatic function.
Femkof should not be administered when metabolic alkalosis due to vomiting of hydrochloric acid is accompanied by loss of sodium (excretion of sodium bicarbonate in the urine).
Active ingredient matches for Femkof:
| Unit description / dosage (Manufacturer) | Price, USD |
| Femkof 100 ml Syrup | $ 0.01 |
| Femkof 50 ml Syrup | $ 0.02 |
List of Femkof substitutes (brand and generic names): | |
| Extin N (Germany) | |
| Fermacidal (Pakistan) | |
| Flemof | |
| Flemof 100 ml Syrup (Pharmacia & Upjohn) | $ 0.01 |
| Forecold | |
| Forecold 100 ml Syrup (Moxy Laboratories Pvt. Ltd.) | $ 0.01 |
| FORECOLD SYRUP 1 bottle / 100 ML syrup each (Moxy Laboratories Pvt. Ltd.) | $ 0.54 |
| FORECOLD TABLET 1 strip / 10 tablets each (Moxy Laboratories Pvt. Ltd.) | $ 0.13 |
| Forecold Syrup (Moxy Laboratories Pvt. Ltd.) | $ 0.54 |
| Formula Pupina | |
| Formula Pupina 100 ml Syrup (Park Pharmaceuticals) | $ 0.02 |
| Gen-Diur | |
| Geohist | |
| Geohist 110 ml Syrup (Shrinivas (Gujarat) Laboratories Pvt. Ltd.) | $ 0.01 |
| Geohist Syrup (Shrinivas (Gujarat) Laboratories Pvt. Ltd.) | $ 0.50 |
| Grakof Expectorant | |
| Grakof Expectorant 110 ml Expectorant (Gracure Pharmaceuticals Ltd.) | $ 0.02 |
| Henadryl | |
| Henadryl 100 ml Syrup (Health Guard (India) Pvt. Ltd.) | $ 0.03 |
| HG Cough | |
| HG Cough 100 ml Syrup (Health Guard (India) Pvt. Ltd.) | $ 0.03 |
| Histadril | |
| Histadril 110 ml Expectorant (Que Pharma Pvt.Ltd) | $ 0.02 |
| HISTADRIL SYRUP 1 bottle / 110 ML syrup each (Que Pharma Pvt.Ltd) | $ 0.51 |
| Histadril Syrup (Que Pharma Pvt.Ltd) | $ 0.51 |
| Histral | |
| Histral 100 ml Syrup (Hiral Labs Ltd.) | $ 0.00 |
| Homeopathic Medicine S33 | |
| Drops; Oral; Ammonium Chloride 30 c / ml | |
| Instaryl D | |
| Instaryl D 100 ml Syrup (Aglowmed Ltd) | $ 0.03 |
| Instaryl D Syrup (Aglowmed Ltd) | $ 0.77 |
| Kof-Kontrol (Australia) | |
| Kofril | |
| Kofril 100 ml Expectorant (Hinglaj Laboratories of India) | $ 0.01 |
| Kufex | |
| Kufex 100 ml Syrup (Lloyds Pharmaceuticals) | $ 0.01 |
| Kumaphyl | |
| Kumaphyl 100 ml Syrup (Kumayun Drugs Private Limted) | $ 0.01 |
| Nomkof B NF | |
| Nomkof B NF 100 ml Syrup (Cadila Healthcare (Zydus Cadila Healthcare Ltd)) | $ 0.02 |
| Nomkof B NF 60 ml Syrup (Cadila Healthcare (Zydus Cadila Healthcare Ltd)) | $ 0.02 |
| Nomkof Exp (India) | |
| Nomkof Exp 100 ml Expectorant (Cadila Healthcare (Zydus Cadila Healthcare Ltd)) | $ 0.02 |
| NOMKOF EXP syr 100ml (Cadila Healthcare (Zydus Cadila Healthcare Ltd)) | $ 0.30 |
| Nospin Paediatric | |
| Nospin Paediatric 50 ml Suspension (Brussels Laboratories Pvt. Ltd.) | $ 0.03 |
| Nyal Bronchitis (Australia) | |
| Nyal Bronchitis Cough Medicine (Australia) | |
| Oricof | |
| Oricof 100 ml Syrup (Orison Pharmaceuticals) | $ 0.02 |
| Oril Expectorant | |
| Oril Expectorant 110 ml Expectorant (Optho Remedies Pvt.Ltd.) | $ 0.01 |
| Osodryl | |
| Osodryl 100 ml Syrup (Osho Pharma Pvt.Ltd.) | $ 0.02 |
| Oyiskof G | |
| Oyiskof G 100 ml Syrup (Oyster Labs Limited) | $ 0.02 |
| PD-LYTE-G (India) | |
| 500ml (Parenteral Drugs) | $ 0.40 |
| PD-LYTE-G infusion 500ml (Parenteral Drugs) | $ 0.40 |
| Pottie's Cough Mixture (Australia) | |
| PV Tussin Syrup | |
| Quino Plasmol Strong Syrup | |
| Quino Plasmol Strong Syrup (Universal Drug House Pvt Ltd) | $ 0.03 |
| Sal Ammoniac | |
See 151 substitutes for Femkof | |
References
- DailyMed. "AMMONIUM CHLORIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "AMMONIUM CHLORIDE". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- PubChem. "ammonium". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
Reviews
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Information checked by Dr. Sachin Kumar, MD Pharmacology
